Free U.S. Shipping Over $60
Core Nutritionals Soothe Inflammation Support
Core SOOTHE offers an additional layer of relief and protection. Formulated with clinically researched ingredients that have proven time and time again to support tissue repair, like those seen from Cissus quadragularis, antioxidant support, from Phyto-C™; and inflammatory suppression, from Boswellia, Curcumin and Ginger Extract. The synergistic nature of these ingredients is unmatched by any product that we have ever seen, as far as suppressing harmful free radical advancement, and aiding in strengthening vital supporting structures is concerned. That's what led us to developing this blend, and that's why you need Core SOOTHE.
Core Soothe Highlights
- Cissus quadrangularis - improved joint integrity and function.
- Boswellia - promotes healthy tendon and cartilage strength..
- Curcumin - suppresses pro-inflammatory compounds
Core Nutrition Soothe Supp Facts
- Cissus Quadrangularis Extract (stem) (5% ketosterones)
Cissus quadrangularis (CQ) is a plant with a long history of use in traditional and folk medicinal systems, including thousands of years of documented use in the Siddha and Ayurvedic traditions. While the specific use of Cissus in these systems varied, the most common traditional preparations related to analgesia, general tonics, and bone fracture healing. More recent research has developed physiological explanations for CQ’s traditional efficacy, including the reduction of pro-inflammatory cytokines, modulation of the glucocorticoid system (in animal trials), and the proliferation of osteoblast (bone-forming cell) DNA.
Specific to bone formation, there is strong data to suggest that CQ increases the accumulation of compounds known as mucopolysaccharides – long chain sugar molecules that precede mineralization in the process of bone formation. Think of these compounds sort of like the wet newspaper before it becomes paper mache. As stated, separate research also suggests that extracts of CQ stimulated osteoblastogenesis, the process of forming bone cells.
- Boswellia Extract (Boswellia serrate) (Gum resin) (65% boswellic acids)
Boswellia is a tree resin extract that is a traditional part of Indian medicine. In modern clinical trials the active agent, boswellic acid, and the gum resin it contains possesses monoterpenes, diterpenes, triterpenes, tetracyclic triterpenic acids, and four pentacyclic triterpenic acids, which are responsible for the inhibition of pro-inflammatory enzymes. Out of the four pentracyclic triterpenic acids, acetyl-11-keto-β-boswellic acid is the most potent inhibitor of 5-lipoxygenase, an enzyme responsible for inflammation. In human study’s, Boswellia has shown effectiveness in the managements of osteoarthritis and other joint related conditions. Several studies proved that Boswellia extract was effective at reducing pain and stiffness, increasing pain threshold, as well as improving overall joint function when compared to placebo. Similarly, to curcumin, boswellic acids have demonstrated a significant attenuation of NF-kB production in various animal and in vitro assays. Curcumin and Boswellia in combination as a treatment method for osteoarthritis has also showed beneficial results. One clinical human trial showed that this combination was able to increase the efficacy of osteoarthritis treatments due to its synergistic effects on oxidative stress reduction.
- Curcumin (Curcuma longa) (95% Curcuminoids)
Curcumin, the primary polyphenol found in turmeric (a root known for its spice), has been the basis of many clinical studies for its therapeutic properties and ability to modulate multiple cells signaling pathways in certain inflammatory diseases known to humans.
- Gingever® (Zingiber officinale) (root) (Ginger Extract 10%)
Ginger is a flowering plant from the Zingiberaceae family with a lengthy history of culinary and medicinal use largely attributed to the therapeutic value of its antioxidant and anti-inflammatory properties.
- Phyto-C™ (Acerola extract, blueberry, strawberry, maqui berry, acai, tart cherry, kale, broccoli, green tea extract, green coffee bean extract, turmeric extract)
Phyto-C™ is a trademarked complex blend of antioxidant rich superfoods clinically formulated to deliver a host of immune system supporting benefits. Combining ingredients such as blueberries, acai, tart cherry, kale, broccoli, green tea, turmeric, and others, you are ensuring that your body is being provided clinically proven and laboratory tested superfoods that will protect against free radicals and other cell destroying compounds. This neutralization of free radicals can protect vital cells, prevent illnesses, and reduce overall inflammation. Inflammation can disrupt normal cell processes thus leading to cell damage and disease. Inflammatory cells produce mediators such as cytokines, arachidonic acid, and other factors, which can precipitate a cascading negative reaction within the body. If this inflammation is not addressed in a reasonable manner, potentially permanent cell damage can occur. The key is to reach a point of equilibrium between free radical formation and antioxidant defense mechanisms. As a potent antioxidant source, Phyto-C™ can provide beneficial antioxidants for the body that can aid in this equilibrium and work to boost the immune system and overall health of the human body
- Bioperine® (Black Pepper Extract) (Piper nigrum) (fruit) (std. to 95% Piperine)
BioPerine® is a patented standardized extract from the fruit of Piper nigrum (black pepper). It’s studied benefits have shown improvements in bioavailability of neighboring nutrients. When suppressing inflammation, overall efficiency and rapid delivery to the targeted cells have a multiplicative impact that enhances the overall therapeutic value of the administered compounds and nutrients. BioPerine® helps to increases the bioavailability and absorption of the aforementioned ingredients within Core Soothe.