{"title":"Core Nutritionals | Clean \u0026 Effective","description":"\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eCore Nutritionals is headed by drug-free pro bodybuilder Doug Miller, and his wife, drug-free pro figure competitor Stephanie Miller. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eThe Miller's founded Core Nutritionals under never-wavering integrity to giving both professional and ''weekend'' athletes the very best in sport's supplementation. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eCore is aiming to set a new industry standard through making products with effective ingredients, proper dosing, in non-proprietary formulas.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"core-nutritionals-fury-preworkout","title":"Core Fury Pre Workout V2","description":"\u003ch2 style=\"text-align: center;\"\u003eCore FURY V2\u003c\/h2\u003e\n\u003cp\u003eCore Fury V2 is a precise mixture of key ingredients that enhance athletic performance and increase mental edge. For athletic performance, l-citrulline, betaine anhydrous, and glycerol are included at, or above, serving sizes suggested by the research. Collectively, these ingredients have been repeatedly demonstrated to increase maximum voluntary contractile force and other measures of power output, increase maximal oxygen uptake capacity, and significantly enhance time measures in standard athletic trials. For cognitive capacity, clarity, and focus, caffeine anhydrous, citicholine, huperzine A, and pregnenolone are also included at, or above, serving sizes suggested by the research. Trials using these ingredients have shown them to increase working memory, reduce cognitive inhibition, and reduce neurological processes typically associated with cognitive decline.\u003c\/p\u003e\n\u003cp\u003eTogether, our performance and focus ingredients constitute the pinnacle of pre-workout formulas. Core Nutritionals has once again introduced the standard in the category.\u003c\/p\u003e\n\u003ch3\u003eCore Fury V2 Supp Facts\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eL-Citrulline\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCitrulline is a non-essential, non-protein amino acid that forms during the urea cycle and forms ornithine when combined with carbon dioxide. Citrulline is also a critical source of endogenous (natural) arginine, as it is rapidly and efficiently converted to arginine in the vascular endothelium and other tissues.\u003c\/p\u003e\n\u003cp\u003eCitrulline’s benefits have been shown to be greater than its parent compound. While arginine undergoes direct hepatic (liver) metabolism through the enzyme arginase, citrulline bypasses hepatic metabolism entirely and it is delivered straight to the bloodstream. The result is that gut absorption and plasma (blood) bioavailability studies comparing citrulline and arginine have shown two things. First, that citrulline is less readily destroyed and has greater absorption than arginine. Second, that citrulline supplementation increases arginine levels more effectively than arginine supplementation itself.\u003c\/p\u003e\n\u003cp\u003eThis translates to promising results. For example, animal studies show a significant increase in anaerobic performance at a 250mg\/kg\/day serving of citrulline, while studies in humans implicate citrulline in both aerobic and anaerobic performance increases. As a critical part of the urea cycle, citrulline’s performance benefits are thought to be a result of its role in ammonia clearance. Citrulline is implicated in reducing the oxygen cost of muscle processes, along with increasing the rate of post-exercise ATP and phosphocreatine replenishment. As ATP and phosphocreatine are the body’s ‘exercise fuel,’ this may result in citrulline delaying time to exhaustion in aerobic and anaerobic exercise.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVasoDrive-AP®\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVasoDrive-AP® is a proprietary ingredient derived from fermented casein. The fermentation process produces two lactotripeptides, Valyl-Prolyl-Proline (VPP) and Isoleucyl-Prolyl-Proline (IPP). Based on the available clinical evidence, these tri-peptides work together to reduce angiotensin converting enzyme (ACE).\u003c\/p\u003e\n\u003cp\u003eIn a recent meta-analysis researchers found 30 studies – all of which were randomized and some of which were double-blind – wherein Valyl-Prolyl-Proline (VPP) and Isoleucyl-Prolyl-Proline (IPP), either alone or in combination, exerted a statistically significant effect on improving endothelial function. In one of the analyzed studies, 25 men were challenged with casein hydrolysate standardized for tri-peptides in a randomized and placebo-controlled design. At the conclusion of the study, forearm blood flow, a key measure of endothelial function, was found to be increased by 33%. The researchers in this and other studies demonstrate that the tri-peptides that constitute VasoDrive-AP® exert an inhibitory effect on ACE. ACE, in turn, is a critical component of the renin-angiotensin (RAS) system, which regulates hemodynamics by controlling plasma fluid volume. While the precise mechanism has not been elucidated, researchers believe that the lactotripeptides in VasoDrive-AP® competitively inhibit ACE, thus decreasing the metabolism of bradykinin and systematically dilating the arteries and veins.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCitrapeak® (glucosyl hesperidin)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCitrapeak®, or glucosyl hesperidin, is a unique substance that contains all of the biological functions of standard hesperidin. Hesperidin is a flavonoid commonly found in citrus fruit peels. Some of these functions include increased vasodilation and increased pump factors. Citrapeak® offers these benefits with increased solubility and bioavailability, making it one of the most effective forms of hesperidin there is.\u003c\/p\u003e\n\u003cp\u003eIn measures of increased blood flow and bioavailability, Citrapeak® was shown to elicit an 18% increase in blood flow when compared against control as well as a feeling of tangible sensations in as little as 30 min. This means that one can receive a quick and efficient pump benefit thus increasing work capacity.\u003c\/p\u003e\n\u003cp\u003eThe proposed mechanism of action for Citrapeak® and hesperidin is that it can acutely stimulate phosphorylation of Src, Akt, AMP kinase, and endothelial NO synthase to produce NO. This increased NO production, while beneficial from a muscle performance standpoint, can also have a positive effect on other factors as well. Clinical studies have shown that hesperidin can increase flow mediated dilation and reduced concentrations of circulating inflammatory biomarkers, such as C-reactive protein, serum amyloid A protein, and soluble E-selectin. So in addition to the exercise performance benefits that hesperidin can provide, it also has been shown to have positive vasculoprotective actions that can benefit the cardiovascular and circulatory system.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBeta Alanine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCarnosine is a bit of an odd duck: we know that it is crucial for muscle function, and that dietary sources of caronsine are essential, but we don’t know precisely how it’s working. Moreover, for decades, we had no idea how to increase intramuscular concentrations, as exogenous carnosine sources degraded in the body so fast as to be effectively useless.\u003c\/p\u003e\n\u003cp\u003eEnter beta-alanine. Simply a different iteration of one of the amino acids that comprises carnosine itself (alanine), beta-alanine has proven to be the most effective means of significantly increasing intramuscular concentrations of carnosine – and therefore of promoting all of carnosine’s various beneficial effects on muscle performance. If that weren’t enough, beta-alanine has also demonstrated beneficial physiological effects independent of its parent compound. In order to understand why, though, we need to first understand some of the basics behind carnosine itself.\u003c\/p\u003e\n\u003cp\u003eCarnosine, a cytoplasmic dipeptide synthesized from the precursors L-histidine and l-alanine, is present in high concentrations in skeletal muscle and plays a pivotal role as a, “chemical buffer” in myocytes (muscle cells). It has long been known that carnosine concentrations are highest in glycolytic, rather than oxidative muscle fibers (roughly speaking, explosive vs., endurance muscle fibers, respectively), and thus long hypothesized that this amino acid is required for sustained performance during supramaximal exercise. Recent research demonstrates that carnosine exerts its physiological effects in long hypoxic (low oxygen) drives by functioning as a high-capacity pH buffer in skeletal muscle, preventing the pH ratio of plasma from dropping too low – and therefore preventing crucial pH-dependent processes such as protein synthesis from being inhibited by acidosis.\u003c\/p\u003e\n\u003cp\u003eDespite its critical role in skeletal muscle anaerobic performance, intramyocellular synthesis of carnosine is rate-limited by the availability of l-alanine. Unfortunately, the majority of literature demonstrates that attempting to increase intramuscular levels of carnosine via either direct carnosine or alanine supplementation is largely ineffective due to carnosine\/alanine pharmacokinetics. Enter beta-alanine. Research with beta-alanine demonstrates consistent and dose-dependent increases to intramuscular carnosine concentrations with beta-alanine supplementation, with certain studies showing an increase of 40-60% with chronic administration. These same literature reveal a synergistic effect of exercise on beta-alanine supplementation, whereby the muscle adaptive changes associated with resistance training promote further intramuscular carnosine production in response to beta-alanine supplementation.\u003c\/p\u003e\n\u003cp\u003eIn simpler language, this essentially means that beta-alanine is a dietary supplement that promotes its own effects in combination with exercise. As you exercise, you simultaneously intensify beta-alanine’s physiological actions – both directly, as well as in the production of intramuscular carnosine. Once ingested, beta-alanine’s exercise-specific beneficial activity is well-established. Elevation of intramuscular caronsine content via beta-alanine supplementation has been shown to improve performance in the following ways.\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eBoth acute and chronic increases in total work capacity, measured by total volume during exercise sessions.\u003c\/li\u003e\n\u003cli\u003eHighly significant increases to TTE (total time to exhaustion), one of the most accurate and comprehensive measures of endurance. In various trials, beta-alanine supplementation has been shown to increase TTE by upwards of 20%.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIncreases to total muscle power output in both acute and chronic trials, suggesting that beta-alanine’s most significant benefit is to those engaging in power-dependent resistance training.\u003c\/p\u003e\n\u003cp\u003eIn total, a significant body of research exists to suggest that beta-alanine may significantly increase muscle power output, strength, training volume and output, overall performance in hypoxic (oxygen-deprived) conditions and peak VO2 max (oxygen holding capacity).\u003c\/p\u003e\n\u003cp\u003eThese myriad benefits make beta-alanine both one of the most-studied, and most well-rounded dietary supplements. Beta-alanine not only has direct, actionable physiological effects, but also promotes critical muscle physiologic adaptations that promote its own effects.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBetaine Anhydrous\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetaine (trimethyl glycine) is found naturally in most living organisms. It is well known to protect non-mammalian animal life in conditions of osmotic stress (a rapid change in the amount of solute surrounding a cell), in addition to functioning as an osmolyte in mammalian (including human) tissues. Betaine is formed in cells as an oxidation product of choline and can be obtained in the diet from foods such as spinach and beets.\u003c\/p\u003e\n\u003cp\u003eThough data on betaine is limited, and recent, the available literature suggests that this compound may have effects in a few areas. Studies on betaine using servings as little as 1.25g\/day and up to 5g\/day for up to 14 days have shown promising results. In one study, a 2.5g\/day serving was found to enhance endurance and total repetition volume for the squat, bench press, and jump squat in in healthy-exercised trained adults. A similar study using the same serving found that betaine use increased peak power and maximum peak power, along with force and the maintenance of both force and power in healthy, exercise-trained subjects.\u003c\/p\u003e\n\u003cp\u003ePerhaps more interesting, however, is a study which examined betaine’s effect on the endocrine system. This study revealed that betaine may exert an effect on several endocrine processes given the proper conditions, causing the authors to hypothesize that long(er) term betaine supplementation may increase the hypertrophic response to resistance training.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSenactiv™ (Panax notoginseng (root) and Rosa roxburghii (fruit) extracts)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSenactiv®, derived from extracts of Panax notoginseng and Rosa roxburghii, has been shown to act in a few pathways to reenergize and rejuvenate cells within the body that take a beating on a daily basis. Ultimately this product falls within a category known as senolytics, or compounds that primarily work to induce cell death. This may not sound ideal as we need our cells to function, but the key is to ensure that these compounds are working on the right kinds of cells. The human body does contain many senescent cells, which are old cells and can be deteriorating. How these senolytics work to promote health is by speeding up the breakdown of these older cells as well as encouraging the grow of new, vibrant cells. The other benefit of Senactiv® and its ingredients is its ability to protect against muscle damage. Ginseng in particular has been shown to help reduce the proinflammatory state that is associated with rigorous training. Where this is going to benefit is to reduce inflammation and jumpstart the recovery process of torn down muscle fibers so these cells can begin to scar and grow stronger. The other benefit that ginseng has been able to show is it has been shown to improve VO2 mas by about 20% when compared to a control group in studies. This improvement can significantly improve oxygen uptake to increase delivery to muscle cells for the ability to push harder and longer.\u003c\/p\u003e\n\u003cp\u003eOn another angle of recovery, Senactiv® has been shown to improve the rate of glycogen storage after exercise. When glycogen can be stored efficiently post exercise it has the ability to attenuate the structural damage associated with training by allowing those carbohydrates and sugars going towards recovery.\u003c\/p\u003e\n\u003cp\u003eSenactiv® is a unique blend of ingredients but with sound research and application behind but with its benefits towards improved cell regeneration, VO2 max, and recovery, it is a great addition to this hydration product.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTaurine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThrough traditionally referred to as an amino acid due to its chemical structure, taurine is not an amino acid in the sense that leucine, alanine, or glutamine are. Its chemical status aside, taurine is considered one of the body’s most essential chemical compounds, as cardiovascular function, muscle development and function, along with optical and nervous systems in the body depend on its abundance. While data on taurine typically occurs with taurine in supplement combinations (with caffeine and other amino acids), these data nevertheless suggest that dietary supplementation with taurine may have beneficial effects on mental focus and alertness and may assist during times of increased physical exertion.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAlbion™ Potassium Glycinate Complex\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePotassium, as sodium’s counterpart, acts as a critical electrolyte primarily by helping to maintain normal levels of fluids inside of our cells. Additionally, it helps muscles to contract and relax, aid in strong nerve function, as well as support normal blood pressure. It works very closely with sodium to create the membrane potential needed for the electrical currents that generate these functions to pass from one cell to the next. While the potassium levels in our body are regulated carefully, a diet lacking sufficient amounts of potassium (especially when combined with excess sodium) or one that contains too much potassium can eventually lead to certain types of dysfunctions and poor health status. When potassium levels in the body increase, the adrenal glands release the hormone aldosterone, which causes the kidneys to excrete excess potassium through the urine. When potassium levels are too low, aldosterone levels are suppressed, which can lead to conservation of potassium thus interfering with balance and negatively affecting transport channels that affect vital bodily functions. Potassium can be gotten from the diet in the form of fresh fruits and vegetables, such as sweet potatoes, beans, tomatoes, spinach and broccoli but supplementing can be an essential application as well to support an active lifestyle where excretion is higher than can be replenished through diet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSea Salt\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSodium is one of the most essential electrolytes for our body to utilize. As sodium is often found bound to chloride as sodium-chloride (salt), their function and benefits are going to be very similar in nature. Sodium helps to keep the water (mainly amount of fluid outside of the body’s cells) and electrolyte balance of the body, while also aiding in the contraction and relaxation of muscles as well as conducting nerve impulses. While only 500mg of sodium is needed per day for these functions to occur, we as active individuals need far more sodium in order to maintain these functions. We mostly lose sodium through sweat and urine, so the more active we are\/the more we sweat and the more we urinate, the more sodium is lost. Acquiring enough sodium through food and drink is crucial to establishing equilibrium again in order to maintain proper functioning and electrolyte balance within the body. The standard American diet is often overloaded with sodium and coupled with inactivity, which can lead to poor health and dysfunction. It is important to engage in physical activity of some kind most days and to eat a diet that is balanced in nutrients in order to maintain proper health.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eL-Tyrosine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTyrosine is amongst a class of amino acids known as ‘non-essential’ amino acids, so called because the body can produce them endogenously, and it is therefore not essential to consume dietary tyrosine. That said, tyrosine is also what is known as a conditionally-essential amino acid; conditionally-essential because, along with glucose and ammonia, the synthesis of tyrosine additionally requires adequate levels of phenylalanine. Once synthesized, tyrosine is one of the most critical amino acids, given its prominent role as a substrate in the synthesis of the catecholamines dopamine, norepinephrine, and epinephrine, in addition to both T3 (triiodothyronine) and T4 (thyroxine) thyroid hormones.\u003c\/p\u003e\n\u003cp\u003eIn studies on stress modulation, tyrosine has been demonstrated to reverse stress-induced norepinephrine depletion and the depressant-behavioral effects normally associated with it. In simpler terms, tyrosine may, in certain conditions, dampen the extent to which norepinephrine is removed from the bloodstream during a stress event. In simpler terms still, tyrosine may help to mitigate the sense of depletion and fatigue felt at the end of a workout.\u003c\/p\u003e\n\u003cp\u003eTyrosine may also play important metabolic functions, mostly related to its role in synthesizing compounds which stimulate the nervous system. While not traditionally considered a sympathomimetic amine, studies which have coadministered tyrosine and stimulants demonstrate a synergistic effect. These studies suggest that tyrosine may potentiate the effects of both endogenous and supplemental norepinephrine and its mimetics (in the case of exogenous use) with respect to lipolysis, thermogenesis, and energy expenditure. Meaning that tyrosine may play a role in assisting norepinephrine to break up triglycerides and increase body heat transiently.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAlpha GPC 50%\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOf the known choline pro-drugs or precursors, Alpha GPC appears to have exert the greatest influence on circulating choline levels. Choline is an essential nutrient involved in numerous metabolic pathways, including DNA regulation and repair, protein function, and metabolism. Perhaps most importantly, the critical neurotransmitter acetylcholine is produced directly from free choline via cholinergic neurons. Acetylcholine is then responsible for several functions itself, most crucially as the compound which induces muscular contraction, and as the neuromodulator partially responsible for modulating risk\/reward, arousal, and enhancing memory.\u003c\/p\u003e\n\u003cp\u003eCholine’s essential role as a substrate for acetylcholine, and therefore brain development, is well documented in animal models. These studies demonstrate that levels of free maternal choline have a direct and fundamental impact on prenatal brain development, with the enhancements or deficits lasting into adulthood. Choline’s enhancing effect is particularly prominent in the hippocampus. In humans, the hippocampus is primarily involved in the consolidation of memory (taking short, episodic memory and translating it into long-term memory) and the learning of new information. Acetylcholine is a critical component in these processes, as mentioned above, and choline may therefore play a potential role in these processes as well by providing the substrate for acetylcholine synthesis.\u003c\/p\u003e\n\u003cp\u003eWhether through these, or other independent mechanisms, a recent trial using Alpha GPC demonstrated a statistically significant increase to power output. In a placebo-controlled, double-blind, randomized trial, 14 healthy volunteers, split into an Alpha GPC or placebo group, were tested on various exercises. In comparison to the placebo group, the Alpha GPC group experienced a 14% increase to bench press. The researchers hypothesize that the peak power increase was the result of a substantial acute increase to growth hormone, one of the observed effects of Alpha GPC supplementation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCocoabuterol® Cocoa Extract\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCocoabuterol®, made up of the bioactive compounds found in cocoa, has been shown through studies and application to have beneficial factors on fat loss, muscle building, and insulin sensitivity. This ingredient exhibits a mechanism of action in the body to increase cAMP (cyclic adenosine monophosphate) levels, which acts as a second messenger and regulator of many movements exhibited by all three types of cells in the human body. In this context, fat (adipose) tissue epinephrine utilizes cAMP to increase to triglyceride hydrolysis and cardiac (heart) muscle epinephrine utilizes it to increase contraction rate. This action can have positive benefits on body composition and performance.\u003c\/p\u003e\n\u003cp\u003eTheobromine, one of the main methylxanthine compounds found in cocoa is primarily effective in the increase of nitric oxide to in the blood stream, which is beneficial to produce the “pump” when ingested pre-workout. Another reaction that can be seen with theobromine is dilation of blood vessels. This can increase blood flow during vigorous exercise leading to increased time to exhaustion but also can pose benefits to individuals who suffer from high blood pressure. Theobromine also has a very high bioavailability and ability to stay in the body for extended periods of time (7-8 hours). Several studies have also looked at the effects of theobromine on human subjects and results have shown its ability to reduce oxidative stress on cells and regulation of gene expression.\u003c\/p\u003e\n\u003cp\u003eCocoabuterol® has also been shown to have positive benefits on reducing oxidative stress in the body. Due to its rich antioxidant properties, it has the ability to fight off free radicals that can be detrimental. In addition to this, the polyphenols that Cocoabuterol® contains have been shown to reduce inflammatory signals within the body that can also be detrimental biomarkers.\u003c\/p\u003e\n\u003cp\u003eBy now you have read some of the amazing benefits of Cocoabuterol® and why we have included in this recomposition agent. When your goal is maintaining muscle mass, shedding body fat, reducing overall stress, and performing at your peak, we make sure you are equipped with the right ingredients, in the right dosages, and for the right purpose. In summary, Cocoabuterol® does all of these things by:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eIncreasing power output due to elevated NO production via theobromine effects.\u003c\/li\u003e\n\u003cli\u003eIncreasing adipose usage through cAMP action in the body.\u003c\/li\u003e\n\u003cli\u003eImproving senses of well-being due to high levels of polyphenols and antioxidants reducing overall stress on the body from workouts and life events.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003ePregnenolone\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePregnenolone, or pregn-5-en-3β-ol-20-one, is known as the grandmother hormone due to its precursor role in the endogenous biosynthesis of most steroid hormones. Pregnenolone also has potent intrinsic activity, however, functioning as a neurosteroid. In that capacity, pregnenolone has been investigated as a mechanistically novel agent for treating cognitive and behavioral symptoms associated with schizophrenia and other mood disorders.\u003c\/p\u003e\n\u003cp\u003ePregnenolone has been demonstrated to enhance learning and memory in animal models at physiologically relevant concentrations. For example, acute administration of pregnenolone or pregnenolone sulfate to rodents results in increased performance along several standardized tests – including maze tests given to rodents to test working memory. Additionally, pregnenolone appears to prevent learning and memory deficits induced by NDMA receptor agonists. These results suggest that pregnenolone’s cognitive functions are at least partially explained by modulating the NMDA receptors – critical receptors involved in numerous neurological processes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCaffeine Anhydrous\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCaffeine is one of the most widely consumed, and perhaps one of the most reviewed, psychoactive compounds. Its physiological effects in a range of areas have been well-documented, including exercise performance, information processing, alertness and mood enhancement, attention, and awareness, along with its anti-lipogenic and lipolytic abilities.\u003c\/p\u003e\n\u003cp\u003eMost importantly to Core FURY, caffeine has been shown to have significant effects on exercise performance, even with ingestion in servings as small 3 to 9mg\/kg\/bw\/day (the equivalent of 2 cups of standard coffee, for a 170lb male). In endurance training, possible explanations for caffeine’s performance-enhancing effects lie in its metabolic effects on both lean and fat tissue. It is suggested that caffeine’s potent lipolytic (the breakdown of fat tissue into fatty acids) and oxidative (the actual ‘burning’ of fat) action allow the body to utilize these sources during prolonged submaximal exercise. As a consequence, muscle glycogen is spared and available for use later in the training session. Practically speaking, this means caffeine is forcing your body to preferentially use fat tissue as a fuel source, while sparing the glycogen which gives you the full-bodied look!\u003c\/p\u003e\n\u003cp\u003eIn short-term exercise, caffeine’s demonstrated role in the inhibition of cyclic AMP- phosphodiesterases (PDE), adenosine receptor antagonism, and adrenoreceptor agonism come into play. These three pathways collectively stimulate lipolytic activity, boost fat metabolism, increase metabolic rate and energy expenditure, and regulate the body’s thermogenic activity. The practical results of activating these pathways are increases to the contractile force of both cardiac and skeletal muscle (harder flexion), an increase in energy expenditure (freeing up more caloric energy to be used in contraction), dilation of vasculature (better blood flow), and improvements to both nitrogen retention and skeletal muscle protein synthesis (key components to muscle building\u003c\/p\u003e\n\u003cp\u003eIn Core FURY, we have included a per-serving amount of caffeine that is neither excessive, nor arbitrary, but that instead reflects the servings used in clinical research.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCaffeine Citrate\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCaffeine citrate is not generally seen in the typical sports performance area. It is more commonly prescribed for premature infants for a short time for the treatment of apnea of prematurity. Apnea of prematurity occurs when a premature infant doesn’t breathe for 15-20 seconds during sleep. In addition to this caffeine citrate can at times be prescribed for migraines in some individuals.\u003c\/p\u003e\n\u003cp\u003eRecently caffeine citrate has gained some popularity in sports performance as it appears to be able to raise blood caffeine levels faster than other caffeine sources. This allows for a quicker feeling of increased energy. For example, typical caffeine levels peak at about 60-120 minutes post ingestion of caffeine anhydrous, whereas blood levels peak around 30 minutes post-ingestion for caffeine citrate. The one drawback to caffeine citrate is that it provides 50% less caffeine per dose than caffeine anhydrous. The specific blend of caffeine sources we have used in Core FURY V2 compliment each other through differing release times, meaning you will have a quick and effective stimulant feeling with caffeine citrate, a fully dosed serving of caffeine anhydrous, as well as a specific delayed release caffeine in Zum-XR® (outlined below) to give you the quick hitting and long-lasting energy you need to get through your workouts.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eZum-XR® Caffeine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eZüm-XR is a patented coating technology that allows the dissolution profile of certain ingredients, primarily caffeine, to have a longer lasting effect in blood serum levels. The release of those ingredients is initiated by an abrasion in the stomach and pH levels between the stomach and the upper gastrointestinal tract. The coating of the microbead technology is a patented timing system with pharmaceutical grade safe polymers. 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Demanding work schedules leave little time for preparing a diet full of the micronutrient-dense foods our bodies require, leaving us scrambling for patchwork solutions. Though we can supplement our diet with a range of solutions, most are too narrow in focus, cause bloating and gas due to lacking digestive enzymes, or are cost prohibitive. Core GREENS attempts to break that mold, providing a whole-food solution to ensure that you can meet your recommended daily intake of not only valuable vitamins and minerals – but also optimize your diet with probiotics, digestive enzymes, and potent anti-oxidants.\u003c\/p\u003e\n\u003cspan\u003e \u003c\/span\u003e\n\u003cp\u003eThe heart of our GREENS formula is our plant blend, constituted by: Psyllium husk, TruServ® (organc kale, broccoli, and spinach), barley grass, wheat grass, chlorella, spirulina and Spectra™. Our 11+ gram scoop provides the function equivalent of several pounds of these greens. Additionally, one scoop serving delivers you 100% of the daily value of 13 vitamins and a range of antioxidants and bioactives. To complement the greens themselves, we have added TruServ® and Spectra™ two industry-leading plant and vegetable\/fruit blends. And lastly, to ensure that GREENS does not cause the bloating and gas associated with many greens products, we have included not only probiotics, but a full-spectrum digestive enzyme blend. Were that not enough, the product tastes fantastic!\u003c\/p\u003e\n\u003cspan\u003e \u003c\/span\u003e\n\u003cp\u003eNow more than ever, your optimal health is too important to leave to chance. Core GREENS is the most convenient and easiest way to deliver to your body the vitamins, minerals, bioactives and antioxidants it requires to function optimally.\u003c\/p\u003e\n\u003ch3\u003eCore Greens Supp Facts\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eTruServ®:\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe TruServ® program is a customizable whole food powder solution by Core Nutritionals’ key partner, Futureceuticals. Core Nutritionals included Futureceuticals’ greens blend, which includes 14 kale leaves, four spinach leaves, and one broccoli floret in each 2g powder serving.\u003c\/p\u003e\n\u003cp\u003eThe benefit of the TruServ program is the verification process. The TruServ Verified® process is FutureCeuticals’ exclusive method of substantiation that connects their extensive production data and the USDA Nutritional database to only our fruit, vegetable and leafy green ingredients. The result is a greens blend verified and substantiated by the USDA itself – giving you additional piece of mind. Each TruServ® blend is organic, fully disclosed, and comes from a dependable and sustainable supply chain.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eSpectra™:\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSpectra™ is the first scientifically validated formula of fruits, vegetables, and herbs shown to inhibit free radical production, optimize cellular metabolic activity, and increase nitric oxide levels within our bodies\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2440\/0931\/files\/Stimulate_antioxidant_activit_within_the_human_body.jpg?v=1587382537\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eSpectra™ represents the latest evolution in the fight against potentially-damaging free radicals. For the first time anywhere, the biological effects of a natural supplement on the changes of oxidative and nitrosative stress markers, as well as cellular metabolic activity, have been clinically observed in the human body. Spectra™ has been reported to decrease ROS, increase cellular oxygen consumption in blood and mitochondria, decrease extracellular H2O2, and reduce TNFα-induced inflammatory response in humans.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003ePsyllium Husk 85% (husk):\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMost of the literature on the beneficial health outcomes of fiber consumption comes from population-level epidemiological studies relying on self-reported fiber intake levels. Problematically, these epidemiological studies often fail to control for residual confounds, making the physiological benefits of fiber less clear.\u003c\/p\u003e\n\u003cp\u003eLuckily, recent evidence in well-controlled, long-term trials using natural fiber supplements such as psyllium husk are beginning to elucidate the benefits of fiber supplementation. Those trials demonstrate that the physical effects of fiber in the small intestine drive metabolic health effects (lowering cholesterol and improving glycemic control); while in the large intestine, fiber can provide a laxative effect. As to the effects in the small intestine, a small trial on cereals, in 345 subjects, showed that the cereals highest in viscosity – psyllium husk is extremely high viscosity – lowered LDL cholesterol by 45% on average.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eChlorella and Spirulina Powder:\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eChlorella and spirulina are the organisms behind the most common forms of green and blue\/green algae, respectively. Chlorella has been variously classified as either a plant or a protist, while spirulina is a kind of cyanobacteria and thus classified as a bacteria. Regardless of the taxonomical differences between chlorella and spirulina, emerging evidence suggests that both have a range of benefits for human health.\u003c\/p\u003e\n\u003cp\u003eThe first benefit is that the macronutrient constituents in the plants themselves are favorable. Spirulina is a source of high-quality protein, γ-linolenic acid, and phycocyanin content. Chlorella, in turn, contains a variety of bioactives, including nucleic acids, amino acids, vitamins, minerals, polysaccharides, glycoproteins, and β-glucans.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eDigestive enzyme blend:\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOne can easily make the argument that dietary enzymes – and in particular, digestive enzymes – are the most consistently underrated and overlooked component to a supplementation regimen. These powerful little protein structures influence or outright control a vast, complex network of bodily functions. In a fitness-specific context, digestive enzymes play an absolutely crucial role in the breaking down of dietary carbohydrates, fats, and proteins into their constitutive parts, and therefore allow your body to use them in various processes (glycogenesis, protein synthesis, etc).\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eProbiotic blend:\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eUnder normal conditions, our gut microbiota – the constellation of intestinal flora that play innumerable physiological roles – are balanced between “good” and “bad” bacteria. The good bacteria confer immunity to us from pathogens, improve digestion of food, help regulate mood and more – while the “bad” bacteria cause a range of pathological conditions, invite pathogens, and generally wreak havoc on our bodies. The point of a well-designed probiotic is maintaining this intestinal balance in the “good” direction.\u003c\/p\u003e\n\u003cp\u003eUsing a probiotic supplement helps offset the microbiotic impact of stressors such as illness, medications (antibiotics), hormonal variations, and an incomplete diet. While the evidence is still emerging, the potential health benefits of probiotics have been seen in many conditions.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin A (as Beta Carotene)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBeta carotene is itself not an essential vitamin but is rather the precursor to the fat-soluble and essential vitamin, vitamin A (Retinol). Like B vitamins, the term vitamin A refers to the compound class retinoids, comprised of retinol, retinal (also called retinaldehyde), retinoic acid, and provitamin A compounds such as beta carotene.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin C (as Ascorbic Acid)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVitamin C is perhaps historically best-known for the treatment and prevention of scurvy, though it has many other roles in the body. For example, vitamin C catalyzes or is a cofactor in eight enzymatic reactions involved in the synthesis of collagen, the nutrient carnitine, and several neurotransmitters necessary for the proper function of the brain.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin D3 (as Cholecalciferol)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVitamin D, in its various forms, is not an essential nutrient – as it is produced endogenously within the body, as a reaction to the skin’s exposure to the sun – and thus not commonly considered a vitamin. Despite its technical classification, vitamin D (a hormone), is nevertheless an import and biologically-active compound, necessary for the calcium homeostasis and metabolism, along with increasing the absorption of magnesium and phosphate.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin E (as Mixed Tocopherols)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVitamin E is another technical misnomer, as the term refers to a group of compounds known as tocopherols with eight biologically-active constituents: alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol. Alpha-tocopherol is the principal bioactive in humans, though the presence of other tocopherols has been linked to beneficial effects.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eB Vitamins (Thiamine, Riboflavin, Niacin, B6 [Pyridoxine], Folic Acid, B12, Biotin, and Pantothenic acid)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eB vitamins are a group of eight essential vitamins with several critical functions in the body. Though both molecularly and physiologically distinct, they are also deeply interrelated in their effects, synthesis and metabolism. Among the B-complex’s many critical roles are energy (protein, carbohydrates, and fat) metabolism, supporting and maintaining the healthy function of the adrenal glands, skeletal muscle function, and digestion.\u003c\/p\u003e\n\u003cp\u003eWhile rates of metabolism and clearance differ between each B vitamin, all B vitamins are water-soluble and are thus not stored in fat. 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We are learning more each day about how the human body works – and in the process, learning that positive adaptations in response to exercise are facilitated by proper nutrition. As a result, more research than ever is being conducted on the value – and specific protocols involved in – peri- or intra-workout nutrition and supplementation. Research is revealing that adequate intra-workout nutrition and supplementation can delay fatigue and increase endurance, facilitate muscle-specific anabolic response to exercise, reduce delayed onset muscle soreness and increase a wide-range of athletic performance metrics.\u003c\/p\u003e\n\u003cp\u003eAt Core Nutritionals, we’ve taken this research seriously and have distilled its results into the most complete and robust intra-workout supplement on the market – Core INTRA. Core INTRA contains a mxi of cutting-edge ingredients and longstanding pillars of supplementation to address most, if not all, major metabolic pathways associated with exercise. Core INTRA’s key ingredients have been demonstrated in scientific research to have a range of positive effects, including, but not limited to:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDelaying fatigue onset\u003c\/li\u003e\n\u003cli\u003eIncreasing maximal voluntary contractile force\u003c\/li\u003e\n\u003cli\u003eIncrease maximal oxygen uptake capacity\u003c\/li\u003e\n\u003cli\u003eReducing delayed onset muscle soreness\u003c\/li\u003e\n\u003cli\u003eIncreasing one rep maximums in bench press and squat\u003c\/li\u003e\n\u003cli\u003eIncreasing localized bloodflow\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEssentially, this product is \u003cem\u003ethe\u003c\/em\u003e intra-workout solution. No more need for mixing and matching, or simply dismissing the valuable role that intra-workout nutrition and supplementation plays. 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More importantly, what should you look for? Let’s be honest: in 2020, taste is paramount to the experience. Amazing taste was our priority for the reformulation of Core PRO – and we succeeded beyond our wildest dreams, if we say so ourselves.\u003c\/p\u003e\n\u003cp\u003eBut this is Core Nutritionals, meaning that function must always match taste and form. Core PRO is no different. While the protein blend in Core PRO was always industry-leading, we have made it even better. Our blend of whey concentrate, whey isolate, and milk protein isolate delivers smooth texture, fast and slow-digesting proteins, and a complete amino acid profile that suits your needs. In other words, have perfected the marriage of TASTE AND PERFORMANCE, and the result is Core PRO.\u003c\/p\u003e\n\u003cp\u003eCore PRO is a clinical-strength, sustained release protein formula, specifically designed to keep you fueled with the right growth\/recovery agents over extended periods of time. This innovative blend provides the perfect arrangement of both fast-uptake and sustained-release proteins, from superior cold-processed whey proteins and micellar casein-rich milk protein sources. This strong synergistic blend helps promote optimal growth and recovery by providing the vital building blocks your body needs, exactly when you need them most. Our superior protein blend contains a generous array of BCAAs (branched-chain amino acids) in their naturally-occurring biological ratios, to delay fatigue and expedite your recovery.\u003c\/p\u003e\n\u003cp\u003eThe benefits don’t stop there. To make this the most effective recovery formula available, we’ve enhanced it with a powerful digestive enzyme blend, including protein-digesting proteases, to improve absorption and accelerate nutrient uptake. The beneficial fatty acids from MCTs (medium chain triglycerides) in Core PRO help preserve lean mass while unleashing your body’s natural metabolic potential. 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That is, deliver a “pump.” The debate surrounding so-called “pump products” is a fair one: are there any physiological benefits to the products? For Core PUMP, this debate is irrelevant – because Core PUMP is not merely a “pump product.” Hence the well-earned tagline, full-spectrum non-stimulant pre-workout.\u003c\/p\u003e\n\u003cp\u003eCore PUMP’s emphasis is what we call a “performance pump” – that is, increasing localized blood flow with a purpose. And the purpose is delivering real, measurable increases to key markers in exercise physiology, such as total time to exhaustion and peak power. We achieve the performance pump in Core PUMP by including ingredients that not only increase dilatory tone – and therefore elicit the “pump” effect – but do so while delivering real performance benefits. Beta Alanine, for example, is well-established to increase endurance, stamina, and peak power output – but it additionally increases blood flow. L-Citrulline is well-established to increase blood flow, but it also increases peak power output. In other words, each ingredient in Core PUMP facilitates the dual purpose behind the performance pump: delivering you the gratifying feeling of a pump, but also servicing your goal of progression.\u003c\/p\u003e\n\u003cp\u003eBeyond its demonstrable performance benefits, PUMP also tastes amazing. We taste tested literally dozens of rounds of PUMP for a flavor matrix that combined amazing taste – which is difficult, if you know the taste of these ingredients! – and a mouth feel that made PUMP eminently drinkable. We think you will agree that we found that combination. Black Lightning, Cherry Burst, and Tropic Thunder are potent enough to deliver the flavor you want, while subtle enough to be sipped and enjoyed – a quality fairly unique to the pump product category, where most products are choked down with a pinched nose.\u003c\/p\u003e\n\u003cp\u003eIn sum, the new Core PUMP represents the best the Core Nutritionals has to offer: amazing formula with a purpose, combined with great taste.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"20 Servings \/ Fun Sweets Orange Cream","offer_id":46699651006706,"sku":"corepumpfsorcm","price":49.95,"currency_code":"USD","in_stock":true},{"title":"20 Servings \/ Fun Sweets Blue Razz","offer_id":44620392464626,"sku":"corepumpfsbue","price":49.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Fun Sweets Cherry Berry","offer_id":44620396167410,"sku":"corepumpfscherry","price":49.95,"currency_code":"USD","in_stock":true},{"title":"20 Servings \/ Cherry Burst","offer_id":32272065593418,"sku":"corepumpcb","price":49.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Tropic Thunder","offer_id":32272065626186,"sku":"corepumptt","price":49.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Blackberry Lemonade","offer_id":32272065658954,"sku":"corepumpbl","price":49.95,"currency_code":"USD","in_stock":true},{"title":"20 Servings \/ Sangria","offer_id":40061489840308,"sku":"corepumpsangria","price":49.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Pink Lemonade","offer_id":44903419478258,"sku":"corepumppl","price":49.95,"currency_code":"USD","in_stock":true},{"title":"20 Servings \/ Strawberry Zolada (Best By 10\/25)","offer_id":47967302025458,"sku":"corepumpstrwz","price":29.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/Pumpcoreorangecream-Large.jpg?v=1726181147"},{"product_id":"core-zone-nootropic","title":"Core Zone Nootropic","description":"\u003ch2 style=\"text-align: center;\" data-mce-fragment=\"1\"\u003eCore Zone by Core Nutritionals\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eResearchers call it the “flow state” – “the mental state in which a person performing some activity is fully immersed in a feeling of energized focus, full involvement, and enjoyment in the process of the activity.” More commonly, and simply, it is known as being in the “zone.” Everyone knows the feeling: eyes narrow, breath becomes deep, time passes quickly, and the world fades away as you focus on the only thing that matters at that moment. What if you could bottle that feeling? Would you?\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cimg alt=\"core zone nootropic\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/imageassetmidstimnootropic_480x480.jpg?v=1667690408\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eWell, we did. Core ZONE represents the pinnacle in nootropic supplementation. Custom-built to get, and keep you, in the zone. Our formula addresses major pathways of cognition and focus with key ingredients at or above clinical serving sizes. Ingredients like ALCAR increase the production of key neurotransmitters involved in producing the flow state, such as serotonin and dopamine – while others such as Bacopa monnieri and NeuroFactor® have been demonstrated in clinical trials to reduce cognitive inhibition, increase working memory, and increase performance on cognitive tasks. In other words, that zoned-in feeling you love bottled and ready for your use whenever you need it.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThis is not another stim-heavy, kitchen-sink formula with something for everyone and nothing for you. No. It is purpose-built, surgically-targeting the cognitive pathways that benefit you most – when you need them the most. So get Core ZONE and get in the zone.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eBreakdown\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcetyl-l-Carnitine:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eL-carnitine is a derivative of the amino acid lysine and, as certain conditions outpace the body’s ability to produce it, l-carnitine is considered a conditionally essential amino acid. While endogenous biosynthesis of l-carnitine from the amino acids lysine and methionine is sufficient for essential processes – along with dietary sources of carnitine from protein-rich red meat, for example – dietary supplementation of carnitine may pose benefits in certain physiological conditions. Unfortunately, due to excess metabolism of l-carnitine by microorganisms in the small intestine, exogenous supplementation with oral l-carnitine has proved ineffective. ALCAR, an acetylated version of l-carnitine, has considerably higher oral bioavailability, due likely to only partial hydrolytic metabolism. Once in the bloodstream, ALCAR plays a fundamental role in the production of energy, acting as the catalyst for the beta-oxidation of long chain fatty acids by the mitochondria; regulating the CoA to Acyl-CoA ratio (necessary for the production of ATP); and the metabolism of carbohydrates. ALCAR also is an excitatory agent for neurons, increases neuronal transmission, and increases the production of neurotransmitters and neurohormones such as dopamine and serotonin.\u003c\/p\u003e\n\u003cp\u003eTyrosine is amongst a class of amino acids known as ‘non-essential’ amino acids, so called because the body can produce them endogenously, and it is therefore not essential to consume dietary tyrosine. That said, tyrosine is also what is known as a conditionally-essential amino acid; conditionally-essential because, along with glucose and ammonia, the synthesis of tyrosine additionally requires adequate levels of phenylalanine. Once synthesized, tyrosine is one of the most critical amino acids, given its prominent role as a substrate in the synthesis of the catecholamines dopamine, norepinephrine, and epinephrine, in addition to both T3 (triiodothyronine) and T4 (thyroxine) thyroid hormones.\u003c\/p\u003e\n\u003cp\u003eIn studies on stress modulation, tyrosine has been demonstrated to reverse stress-induced norepinephrine depletion and the depressant-behavioral effects normally associated with it. In simpler terms, tyrosine may, in certain conditions, dampen the extent to which norepinephrine is removed from the bloodstream during a stress event. In simpler terms still, tyrosine may help to mitigate the sense of depletion and fatigue felt at the end of a workout.\u003c\/p\u003e\n\u003cp\u003eTyrosine may also play important metabolic functions, mostly related to its role in synthesizing compounds which stimulate the nervous system. While not traditionally considered a sympathomimetic amine, studies which have co-administered tyrosine and stimulants demonstrate a synergistic effect. These studies suggest that tyrosine may potentiate the effects of both endogenous and supplemental norepinephrine and its mimetics (in the case of exogenous use) with respect to lipolysis, thermogenesis, and energy expenditure. Meaning that tyrosine may play a role in assisting norepinephrine to break up triglycerides and increase body heat transiently.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTaurine:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThrough traditionally referred to as an amino acid due to its chemical structure, taurine is not an amino acid in the sense that leucine, alanine, or glutamine are. Its chemical status aside, taurine is considered one of the body’s most essential chemical compounds, as cardiovascular function, muscle development and function, along with optical and nervous systems in the body depend on its abundance. While data on taurine typically occurs with taurine in supplement combinations (with caffeine and other amino acids), these data nevertheless suggest that dietary supplementation with taurine may have beneficial effects on mental focus and alertness and may assist during times of increased physical exertion.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCiticoline (Cytidine 5’-diphosphocholine):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCholine is an essential nutrient involved in numerous metabolic pathways, including DNA regulation and repair, protein function, and metabolism. Perhaps most importantly, the critical neurotransmitter acetylcholine is produced directly from free choline via cholinergic neurons. Acetylcholine is then responsible for a number of functions itself, most crucially as the compound which induces muscular contraction, and as the neuromodulator partially responsible for modulating risk\/reward, arousal, and enhancing memory.\u003c\/p\u003e\n\u003cp\u003eCholine’s essential role as a substrate for acetylcholine, and therefore brain development, is well documented in animal models. These studies demonstrate that levels of free maternal choline have a direct and fundamental impact on prenatal brain development, with the enhancements or deficits lasting into adulthood. Choline’s enhancing effect is particularly prominent in the hippocampus. In humans, the hippocampus is primarily involved in the consolidation of memory (taking short, episodic memory and translating it into long-term memory) and the learning of new information. Acetylcholine is a critical component in these processes, as mentioned above, and choline may therefore play a potential role in these processes as well by providing the substrate for acetylcholine synthesis.\u003c\/p\u003e\n\u003cp\u003eCiticoline (Cytidine 5’-diphosphocoline), also known as CDP-choline, is a potentially superior form of choline due to its ability to cross the blood brain barrier. In fact, most studies with neurological or nootropic effects used this form. In that regard, studies in otherwise healthy, normal adults demonstrated meaningful and statistically significant impacts on working memory, recall, and attention.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMucuna pruriens:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMucuna pruriens is one of the popular medicinal plants of India and is known to contain various beneficial nutritional compounds. The main nutrient found in Mucuna pruriens is L-dopa, which acts as a natural source of dopamine. Prolactin is a hormone released by the pituitary gland, which is believed to exert anti-androgenic effects in men. Mucuna pruriens’ ability to support healthy dopamine levels may significantly reduce the release of prolactin hormone by the pituitary glands offering powerful benefits. In addition, clinical evidence suggests that Mucuna pruriens not only supports healthy growth hormone levels but also contains naturally occurring serotonin precursors to support mood, memory, and overall well-being. Clinically shown to support optimal balance of growth hormone, prolactin, serotonin and other beneficial hormones, Mucuna pruriens may also assist healthy weight management and stress support.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBacopa monnieri:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBacopa monnieri, also known as the water hyssop commonly, or as Brahmi in Ayurvedic texts, is a small creeping herb endemic to sub-tropical India. The herb has been used in traditional Indian medicine for well over one thousand years, with its first recorded usage coming in the 6th century A.D. In this traditional context, BM has been used for a wide-range of purposes, including as a treatment of asthma and epilepsy.\u003c\/p\u003e\n\u003cp\u003eMore recently, BM has been the subject of numerous cognition and memory trials, as the plant has a well-established nootropic effect. Likely through modulation of the serotonin reuptake system, clinical trials in healthy humans have demonstrated that BM possesses a significant effect on the retention of newly-learned information. In several trials utilizing a 300mg daily serving, BM was also shown to decrease the recall delay of newly learned information and reduce short term forgetfulness – suggesting that the herb’s effect on the serotonic and cholinergic systems are increasing the encoding (the literal storing) of memory information.\u003c\/p\u003e\n\u003cp\u003eBeyond cognition and memory encoding, BM has also been demonstrated to function as a potent adaptogen and relaxant – which in the Core ZONE formula may help to smooth the effect curve of the product’s stimulants, reducing jitteriness or, “crash.”\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCaffeine Anhydrous:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCaffeine is one of the most widely consumed, and perhaps one of the most reviewed, psychoactive compounds. Its physiological effects in a range of areas have been well-documented, including exercise performance, information processing, alertness and mood enhancement, attention, and awareness, along with its anti-lipogenic and lipolytic abilities.\u003c\/p\u003e\n\u003cp\u003eMost importantly to Core ZONE, caffeine has been shown to have significant effects on daily performance where energy is needed, even with ingestion in servings as small 3 to 9mg\/kg\/bw\/day (the equivalent of 2 cups of standard coffee, for a 170lb male). One study in particular looked at the effects of caffeine on sleep deprived and heavily fatigued military personnel, a job where alertness and attention are extremely important, and found that caffeine did possess positive benefits on these attributes. The study concluded that:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eCaffeine has a positive effect on reaction time and attention during psychomotor tasks. This can also include driving or computer related tasks.\u003c\/li\u003e\n\u003cli\u003eMood and alertness are positively affected by caffeine in doses between 75mg and 300mg.\u003c\/li\u003e\n\u003cli\u003eCaffeine has a low toxicity and produces no serious physiological side effects in adults.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhen it comes to exercise, possible explanations for caffeine’s performance-enhancing effects lie in its metabolic effects on both lean and fat tissue. It is suggested that caffeine’s potent lipolytic (the breakdown of fat tissue into fatty acids) and oxidative (the actual ‘burning’ of fat) action allow the body to utilize these sources during prolonged submaximal exercise. As a consequence, muscle glycogen is spared and available for use later in the training session. Practically speaking, this means caffeine is forcing your body to preferentially use fat tissue as a fuel source, while sparing the glycogen which gives you the full-bodied look!\u003c\/p\u003e\n\u003cp\u003eIn short-term exercise, caffeine’s demonstrated role in the inhibition of cyclic AMP- phosphodiesterases (PDE), adenosine receptor antagonism, and adrenoreceptor agonism come into play. These three pathways collectively stimulate lipolytic activity, boost fat metabolism, increase metabolic rate and energy expenditure, and regulate the body’s thermogenic activity. The practical results of activating these pathways are increases to the contractile force of both cardiac and skeletal muscle (harder flexion), an increase in energy expenditure (freeing up more caloric energy to be used in contraction), dilation of vasculature (better blood flow), and improvements to both nitrogen retention and skeletal muscle protein synthesis (key components to muscle building).\u003c\/p\u003e\n\u003cp\u003eIn Core ZONE, we have included a per-serving amount of caffeine that is neither excessive, nor arbitrary, but that instead reflects the servings used in clinical research to give such benefits that can be useful wherever heightened focus and energy are needed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNeuroFactor®:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNeurofactor®, an extract derived from the whole fruit Coffea arabica plant, is a clinically proven ingredient shown to stimulate the production of the neuroprotein, Brain-Derived Neurotrophic Factor (BDNF). BDNF has been shown to be crucial in the development, maintenance and repair of neurons and also protect against neuro-degenertion. One study comparing other coffee, caffeine, and polyphenol compounds, showed that they were not statistically significant in increasing BDNF % compared to NeuroFactor®. The unique polyphenol profile found in NeuroFactor® showed to be superior in increasing BDNF concentration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHuperzia serrata Extract (leaf and stem) (1% Huperzine A):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eHuperzia serrata\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis a compound found in the plant families of Huperziaceae, Lycopodiaceae, and Selaginella and is endemic to China. The Lycopodium alkaloid Huperizine-A, found in Core ZONE, was first isolated from a folk medicinal preparation in 1984.\u003c\/p\u003e\n\u003cp\u003eDue to the potent anticholinesterase activities of Huperzine A, the compound was been evaluated in numerous in vitro, in vivo, and human trials. These data suggest that Huperzine’s Ache activities are most potent in the cortex, hippocampus, and striatum (at least in rats) – key regions in the brain responsible for forming, coordinating, and recalling memory. These effects are assisted by Huperzine A’s high oral bioavailability. Studies using microdialysis technique in rats, for example, showed that the response to Huperzine A was dose-dependent and substantially lowered the level of ACh in cortex.\u003c\/p\u003e\n\u003cp\u003eHuperzine A has also shown promise in humans. Used as a reversible inhibitor of acetylcholinesterase, Huperzine A has shown positive benefits on cognition and as a therapy for individuals suffering from Alzheimer’s Disease. This is partly due to its inhibitory factors on acetylcholine but also its neuroprotective properties. In another study on memory and learning performance, 34 pairs of middle school students complaining of memory inadequacy were given a small dose of Huperzine A. The students were then match paired along a number of vectors and provided tests on working memory. The results of this study exhibited that HupA markedly improved the memory function of adolescent students\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePregnenolone\u003c\/b\u003e\u003cstrong\u003e:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePregnenolone, or pregn-5-en-3β-ol-20-one, is known as the grandmother hormone due to its precursor role in the endogenous biosynthesis of most steroid hormones. Pregnenolone also has potent intrinsic activity, however, functioning as a neurosteroid. In that capacity, pregnenolone has been investigated as a mechanistically novel agent for treating cognitive and behavioral symptoms associated with schizophrenia and other mood disorders.\u003c\/p\u003e\n\u003cp\u003ePregnenolone has been demonstrated to enhance learning and memory in animal models at physiologically relevant concentrations. For example, acute administration of pregnenolone or pregnenolone sulfate to rodents’ results in increased performance along several standardized tests – including maze tests given to rodents to test working memory. Additionally, pregnenolone appears to prevent learning and memory deficits induced by NDMA receptor agonists. These results suggest that pregnenolone’s cognitive functions are at least partially explained by modulating the NMDA receptors – critical receptors involved in numerous neurological processes.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"20 Servings \/ Arnold Palmer","offer_id":42233204375794,"sku":"corezonearnold","price":39.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Sour Candy","offer_id":42233204441330,"sku":"corezonesourcandy","price":39.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/ZONE-Arnold-Palmer_1800x1800_f03d1459-dfda-4647-9086-47996b600d40.png?v=1608343138"},{"product_id":"core-zzz-sleep-aid","title":"Core ZZZ Sleep Aid","description":"\u003ch2 data-mce-fragment=\"1\"\u003eCore Zone by Core Nutritionals\u003c\/h2\u003e\n\u003cp\u003eYou know the feeling: the weights feel heavy, the treadmill feels painfully slow, and every minute you’re looking up at the clock wondering when the workout is going to be over. Why? It’s not your diet – your food journal is so detailed it makes engineers blush. It’s not your supplementation – you are using the entire Core lineup like every smart trainer does. Ah, that’s right. Last night was a brutal mashup of tossing and turning set to the tune of your spouse’s snoring and the neighbor’s dog barking.\u003c\/p\u003e\n\u003cp\u003eIf recovery is the key to success, then say “hello” to the locksmith. Core ZZZ is a perfectly-designed product with a single goal in mind: maximizing your recovery. We have included only the best and most effective recovery agents, at the proper serving sizes, to take the guesswork out of a good night’s rest. We have also specifically chosen these ingredients for the pathways they target, ensuring that every possible physiological pathway for recovery is covered.\u003c\/p\u003e\n\u003cp\u003eNo more tossing nights and no more wasted workouts – put recovery at the top of your list by putting Core ZZZ at the center of your supplement lineup.\u003c\/p\u003e\n\u003ch2 data-mce-fragment=\"1\"\u003eBreakdown\u003c\/h2\u003e\n\u003cp\u003eMineral blend (Vitamin B-6 (as Pyridoxine HCL), Magnesium (as Magnesium aspartate), and Zinc (as Zinc monomethionine)):\u003cbr\u003e\u003cbr\u003eSleep is important, but sleep is not important for its own sake. Rather, we sleep because of the collection of physiological processes that it enables: the repair of tissue, the biosynthesis and release of hormones, and so on. While each of the individual ingredients in our mineral blend is important in this regard, the formulation as a whole has previously been demonstrated to have tangible physiological effects.\u003cbr\u003e\u003cbr\u003eIn a randomized, double-blind, placebo-controlled study, 27 NCAA football players consumed a supplement containing Vitamin B-6, Magnesium, and Zinc, or placebo, for an 8-week period. Measurements for free testosterone, IGF-1, and muscle strength and power were taken at the conclusion of the study. The authors found statistically significant increases to all measured indices, with a particularly high spike in free testosterone as compared to placebo.\u003cbr\u003e\u003cbr\u003eGamma-aminobutyric acid (GABA):\u003cbr\u003e\u003cbr\u003eGABA, known technically as, γ-Aminobutyric acid, is a potent depressive and the chief inhibitory neurotransmitter in the human brain. As GABA plays a critical role in the sedative and depressive functions of the brain, GABA receptor subtypes – principally GABAA – have been positively associated with the regulation of the sleep-wake cycle.\u003cbr\u003e\u003cbr\u003eGiven its pivotal status in the regulation of sedation and sleep, both GABA itself as well as GABA agonists (GABAergics) have been researched for their capacity to modulate sleep and mood. A 1996 animal model study established that stimulation of the GABAA receptor-subtype through exogenous GABA intake led an increase in the length of slow-wave sleep. A further 2006 study found that increasing plasma levels of GABA through supplementation was associated with regulation of the posterior hypothalamus “sleep-wake switch,” a physiological mechanism used to control sleep in mammals.\u003cbr\u003e\u003cbr\u003eIn addition to GABA’s potential role in the regulation of sleep itself, additional research has uncovered that GABA may potentiate certain benefits of deep sleep – namely, the increase in plasma growth hormone. The first study to demonstrate GABA’s growth-hormone potentiating effect was a 1980 study in 19 healthy subjects. This placebo-controlled trial found that a 5 gram serving of GABA significantly increased plasma levels of growth hormone as compared to controls. A further study in 2008 demonstrated similar results, with 50% increases in plasma levels of certain growth hormone isoforms in response to GABA administration in healthy subjects.\u003cbr\u003e\u003cbr\u003eL-Glycine:\u003cbr\u003e\u003cbr\u003eL-Glycine is a non-essential amino acid, so-called because the human body is capable of synthesizing glycine from sources internal to the body (serine). Like many other amino acids, glycine possesses physiological effects independent of its function as a ‘building block’ to protein. In glycine’s case, its physiological effects stem from its role as a neurotransmitter in the human brain.\u003cbr\u003e\u003cbr\u003eThree methodologically-sound studies have investigated glycine’s effect on sleep and sleep quality in humans – and each used the same serving size as that found in Core ZZZ, 3 grams. In studies conducted in 2006 and 2007, ingestion of 3 grams of glycine prior to sleep was found to have both subjective and objective positive effects on sleep. Subjectively, participants reported more satisfactory sleep, less daytime sleepiness, and improved cognitive function. Objectively, PSG measurements revealed less latency to sleep onset and deep sleep. These results were confirmed in a more recent 2012 study which focused principally on glycine-dependent improvements to daytime cognitive function in sleep-deprived volunteers.\u003cbr\u003e\u003cbr\u003eOverall, these human trials suggest a possible role for glycine in the regulation of beneficial sleep cycles at a serving size of 3 grams.\u003cbr\u003e\u003cbr\u003eL-Tryptophan\u003cbr\u003e\u003cbr\u003eL-Tryptophan is an essential amino acid, and one of the most critical in the human body. Tryptophan is critical because it is the biological precursor to both serotonin (one of the body’s principal neurotransmitters regulating mood, appetite, and sleep) and niacin (a vitamin and a crucial biological intermediate).\u003cbr\u003e\u003cbr\u003eAmong dietary supplements or ingredients purported to regulate the sleep-wake cycle, tryptophan is perhaps the most well-studied. The body of literature pertaining to tryptophan’s sedative effects is vast and varied, reaching back at least 40 years and featuring hundreds of articles. Despite the enormity of this body of literature, and therefore potential for disagreement or conflicting data, scientific consensus exists that tryptophan exerts positive effects on the regulation of the sleep wake cycle in humans – evinced by placebo-controlled trials in humans.\u003cbr\u003e\u003cbr\u003eOne such placebo-controlled, double-blind trial involved 10 healthy volunteers ingesting either 1.2 grams or 2.4 grams of tryptophan prior to sleep. Blood and urine measurements were taken at regular intervals, and sleep was measured both objectively (latency to sleep) and subjectively using the Stanford Sleepiness scale. Both serving sizes of tryptophan were highly correlated with a significant reduction in sleep latency and significant improvements to subjective sleep quality on the Stanford Sleepiness Scale.\u003cbr\u003e\u003cbr\u003eResults such as this have been reproduced in dozens of clinical trials involving healthy\/normal and sleep-disturbed subjects, men and women, younger and older participants, and featuring serving sizes as low as 500mg and high as 15 grams. These studies nearly universally reflect that exogenous tryptophan supplementation is positively correlated with an improvement in sleep quality and an objective reduction in sleep latency – with the best effect’s resultant from a 1 gram to 1.5 gram serving size.\u003cbr\u003e\u003cbr\u003eL-Ornithine HCL:\u003cbr\u003e\u003cbr\u003eL-Ornithine is a non-protein amino acid, meaning that, unlike most other amino acids, it is not involved in the production of proteins and is not encoded by DNA. In humans, ornithine is most commonly associated with the urea cycle, though recent research has revealed a potential role for ornithine in the regulation of sleep and arousal.\u003cbr\u003e\u003cbr\u003eThough data on ornithine is not extensive, recent research has demonstrated that it may play a role in both objective and subjective assessments of sleep quality in humans. In a double-blind, placebo-controlled, randomized trial, 400mg or placebo was administered to 52 healthy adults experiencing mild fatigue. Ornithine was consumed consecutively for 8 weeks, with measurements for cortisol being collected – along with both subjective and objective measures of sleep quality.\u003cbr\u003e\u003cbr\u003eAt the conclusion of the trial, most participants experienced both subjective and objective improvements to the quality of their sleep. The researchers also noted that ornithine supplementation resulted in a small but statistically significant reduction to plasma concentrations of cortisol.\u003cbr\u003e\u003cbr\u003eMucuna pruriens Extract (seed) (50% L-dopa):\u003cbr\u003e\u003cbr\u003eMucuna pruriens is a hanging or climbing plant endemic to India and sub-Saharan Africa. The plant has been used extensively in the Indian traditional medicinal system known as Ayurveda for a number of purposes, including virility and gastrointestinal disorders.\u003cbr\u003e\u003cbr\u003eIn the context of recovery, data is limited but promising. In a 2012 study, 18 healthy men and women with impaired sleeping were given a supplement containing Velvet Bean (MP) for 28 days. At the conclusion of the study, the participants completed the well-regarded and industry-standard Pittsburgh Quality Sleep Index.\u003cbr\u003e\u003cbr\u003eThe authors note that supplementation with the Velvet bean-containing product improved the reported scores in every category of the PQSI. Many categories saw improvements of over 50%. Moreover, the authors noted both that Velvet Bean, not the other ingredient in the studied supplement, was the bioactive compound responsible for these effects, and that Velvet Bean has been demonstrated to improve GH release during sleep in other independent trials.\u003cbr\u003e\u003cbr\u003eL-Theanine:\u003cbr\u003e\u003cbr\u003eL-Theanine is a non-protein amino acid found mostly in green tea. The structure of L-Theanine closely resembles L-glutamic acid and has a mechanism of action they may be mediated through glutamate receptors, a possibility supported by its partial co-agonistic effect on the N-methyl-D-aspartate receptor. Due to L-Theanine being a widely ingested phytochemical during normal every day life, it has the potential to be an ingredient in many nutraceutical applications due to its proposed benefits on cognitive function and neuroprotective properties. L-Theanine has been studied in several instances on its benefits in these areas. In humans, L-Theanine has been shown to play a beneficial role in tasks requiring heightened focus and attention as well as positive effects on mental state, including improved sleep quality. A four week, randomized, placebo controlled and double-blind study consisting of 30 individuals assessing L-Theanine’s influence on stress related symptoms and cognitive function resulted in positive outcomes. At 200mg per day results revealed positive benefits sleep quality, decreased sleep disturbance, and reduced need for sleep medication. For cognitive function, verbal fluency and execution during concentration required tasks was also increased. The benefits of L-Theanine have mostly been studied for its acute effects on the user. Long term effects can likely be seen by how the acute affects influence changes in lifestyle. However, studies like this are promising on the benefits of L-Theanine.\u003cbr\u003e\u003cbr\u003e5-HTP (5-hydroxytryptophan):\u003cbr\u003e\u003cbr\u003eSerotonin has often been at the center of the discussion in the regulation of sleep. This “feel good” hormone has been shown to be essential in many physiological functions including circadian rhythm, thermoregulation, cognition, and nociception. When serotonin levels are low, it is critical to find ways to restore balance. Supplementation, to help with recovery and sleep, can be beneficial in reducing stress and restoring this balance. 5-HTP (5-hydroxytryptophan) is a natural chemical compound that has been shown to benefit certain aspects of health, including mental function and sleep quality as it is a natural precursor to serotonin in the brain. 5-HTP passes the blood brain barrier easily, making it very efficient in its action. 5-HTP, when combined with other nutrients such as GABA, may be effective at decreasing time required to fall asleep and improving sleep quality and duration.\u003cbr\u003e\u003cbr\u003eMelatonin:\u003cbr\u003e\u003cbr\u003eIrregular sleep is a problem that is common amongst the population and most are often searching for remedies to improve sleep quality and circadian rhythms. Melatonin is a neurohormone that is secreted by the pineal gland known for its sleep regulation properties. Its secretion is often suppressed by light, which when this occurs can often disrupt normal sleep patterns. When sleep patterns are disrupted and irregular, it has the ability to increase risks of certain health issues and premature aging. Supplementation exerts most of it benefits through decreased sleep latency and increased onset of sleep. This can also be related to its ability to work with the biochemistry and decrease body temperature in users. Supplementation with melatonin is the most efficient way to increase melatonin levels prior to sleeping. However, diet and improvements in quality of life are also ways to improve normal melatonin secretion as well as normal circadian rhythm for better quality sleep.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"20 Servings \/ Pineapple Peach","offer_id":44380532211954,"sku":"corezzz-1","price":39.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Blueberry Lemonade","offer_id":44380532244722,"sku":"corezzz-2","price":39.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/ZZZ_BL_Front_1_1800x1800_a5730f61-19a1-4d55-aa73-6303c3b2454c.jpg?v=1759475458"},{"product_id":"core-hard-extreme-advanced-recomp-hardening","title":"Core Hard Extreme","description":"\u003ch2 data-mce-fragment=\"1\" style=\"text-align: center;\"\u003eHard Extreme by Core Nutritionals\u003c\/h2\u003e\n\u003cp\u003eTo be hard, you need to get HARD. It's that simple.\u003c\/p\u003e\n\u003cp\u003eCore HARD is the pinnacle in recomposition supplementation. The ingredients in HARD have been specifically chosen to balance your hormonal environment and maximize your lean mass.\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e3 scoops per serving.\u003c\/li\u003e\n\u003cli\u003e28 servings per container.\u003c\/li\u003e\n\u003cli\u003eBody recomposition.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eYour diet is impeccable and couldn’t be any more in check – macros, micros, you have it all down. Your workouts? Get out of here! You have slaved, grinded, and grunted your way through leg workouts so intense the gym staff cried – and those were on your worst days. And yet, something is missing.\u003c\/p\u003e\n\u003cp\u003eIt’s that “extra” level of shred, “that look.” You know exactly what we mean. That type of leanness and density that makes an arm look twice as big, a stomach look twice as lean, and a forearm look like a roadmap for the Italian countryside. It’s that kind of elusive hardness that’s so rare, most of us simply chalk it up to genetics, or luck, or steroids, or whatever excuse we have handy – and yet we all still want it.\u003c\/p\u003e\n\u003cp\u003eThe reality? It isn’t all that unattainable. Getting “that” look, “that” hardness, is about balance and recomposition. It’s a matter of adding in that final piece of the puzzle that makes the entire picture come out perfectly.\u003c\/p\u003e\n\u003cp\u003eTo be hard, you need to get HARD. It’s that simple.\u003c\/p\u003e\n\u003cp\u003eCore HARD is another product in the Core Nutritionals’ lineup to follow the basic, but indispensable principles that Core Nutritionals is slowly making an industry standard: create products with effective ingredients, in effective doses, in a non-proprietary formula. This time around, we have applied those principles to the problem of softness that we all despise and have developed the most advanced ultra-hardening and recomposition agent on the market.\u003c\/p\u003e\n\u003cp\u003eTaking advantage of both the old and the new, Core Nutritionals has employed both modern, cutting-edge compounds and traditional herbs to create a balanced approach to delivering hardness. Key ingredients in Core HARD affect some of the body’s critical physiological pathways, combining sexiness and science in a single, non-proprietary formula. We have included seven powerful ingredients into a full month's worth of stimulant free, recomposition goodness.\u003c\/p\u003e\n\u003ch2 data-mce-fragment=\"1\"\u003eBreakdown\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003ePhysiological Properties and Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKSM-66® Full-Spectrum Ashwagandha Extract (Withania somnifera) (root) (5% withanolides)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eWithania somnifera Dunal\u003c\/em\u003e, colloquially known as Winter Cherry or Indian Ginseng, is an herb that features prominently in the traditional Indian medicinal system of Ayurveda. Known as Ashwagandha in Ayurveda,\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eWithania somnifera\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis a critical ingredient in various Ayurvedic tonics and tinctures prepared as a traditional remedy for the treatment of various ailments.\u003c\/p\u003e\n\u003cp\u003eRecently identified as a potent adaptogenic and target for therapeutic applications, Ashwaghanda has been the subject of numerous animal, pre-clinical, and clinical trials designed to examine its potential effects as an antioxidant, anti-carcinogenic, anxiolytic, antibacterial, antifungal, and immonumodulating compound. Ashwaghanda’s broad therapeutic potential is hypothesized to be the result of its robust phytochemical profile, including a wide swath of alkaloids, sitoindosides, and the highly biologically active withanolide group. As the principally biologically active compounds within Ashwaghanda, withanolides such as withanone, withaferine A, withanolides A, D, and G have been identified, isolated, and extensively studied in the various applications noted above.\u003c\/p\u003e\n\u003cp\u003eIn recognition of the potential physiological benefits of withanolides, Core Nutritionals selected KSM-66\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eto include in its HARD formula. KSM-66\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eis a full-spectrum Ashwaghanda extract, standardized for 5% withanolides – meaning that KSM-66\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003enot only includes the full range of biologically active compounds within Ashwaghanda, but also that it contains the highest currently available concentration of the principally active withanolides (5%).\u003c\/p\u003e\n\u003cp\u003eThe high concentrations of withanolides within KSM-66® has resulted in encouraging results in a number of human, clinical trials – particularly considering many of these trials were conducted using the methodological gold standard of randomization, double-blind delivery, and placebo control. Amongst the most impressive results contained in these trials:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eA 27.9% reduction in serum cortisol levels, measured over 60 days in a trial featuring 64 chronically stressed adults.\u003c\/li\u003e\n\u003cli\u003eStatistically significant increases to endurance and stamina, as measured by VO\u003csup\u003e2\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003emax, in a clinical trial featuring 50 healthy, exercise-trained adults.\u003c\/li\u003e\n\u003cli\u003eIncreased measures of well-being as reported by self-assessment scales, included in both the clinical trials mentioned above.\u003c\/li\u003e\n\u003cli\u003eStatistically significant increases in serum testosterone levels in a clinical trial featuring 68 infertile men.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThough each of these results is impressive, perhaps the most significant is the 27.9% reduction in cortisol seen in the 60 day trial. As detailed above, cortisol possesses a multitude of potentially degradative physiological effects, including: inhibiting glucose uptake, causing a constriction of the vasculature (vasoconstriction), the breakdown of glycogen, and inarguably the result most would desire to avoid, proteolysis (the breakdown of muscle tissue).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePhosphatidylserine (50%)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePhosphatidylserine, colloquially known as PS, is a nearly ubiquitous phospholipid found in various membranous tissues throughout the body. PS’s ubiquity coincides with its necessity for crucial physiological functions, as the phospholipid is implicated in several components of cell communication, as well as the mediation of catecholamine synthesis and transmission in the brain (along with other neuroendocrine functions). In a fitness-related context, a nascent but growing body of methodologically-sound research suggests that PS may play a role in increasing exercise capacity.\u003c\/p\u003e\n\u003cp\u003eStudies administering the compound in both acute and chronic fashion suggest that PS has a measurable effect on exercise capacity. In a double-blind, placebo-controlled, randomized trial involving 16 trained athletes, phosphatidylserine was administered for 10 days prior to an acute exercise challenge. Exercise markers such as exercise time to exhaustion, sprint performance, and ratings of perceived exertion, were measured post-exercise. The authors found that exercise time to exhaustion was significantly altered. Related studies using similar serving sizes have found that chronic PS administration increased shot accuracy in golfers, increased exercise time to exhaustion by 28% in cyclists, and reduced subjective feelings of stress and soreness in others.\u003c\/p\u003e\n\u003cp\u003eOverall, phosphatidylserine appears to play a valuable role in the increase in exercise capacity. PS may therefore play a critical role in the continued exercise success of bodybuilders in a, “cutting” or recomposition stage.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePomegranate Extract (Punica granatum) (hull) (ellagic acid 40%)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePomegranate is a fruit-bearing deciduous shrub, endemic to and cultivated in wide swaths of both Europe and Asia. Pomegranate is also the predominant member of two species comprising the Punicaceae family\u003c\/p\u003e\n\u003cp\u003ePomegranate fruit has long been consumed as a dietary staple, and recent research has uncovered that the peel, in particular, harbors a broad range of physiologically active compounds known as polyphenols – most prominently ellagitannins. When consumed, these ellagitannins are hydrolyzed to ellagic acid in the gut, and released into the blood, allowing ellagic acid to be widely distributed to many target tissues and organs. \u003c\/p\u003e\n\u003cp\u003eWhile still preliminary, emerging animal and in vitro data on PME (pomegranate extract) suggests that both specific and whole plant extracts may exert interesting endocrine effects. In a study examining the effects of PME on cultured human cells, PME was shown to down-regulate estrogen-receptor gene expression, and inhibit binding – suggesting that PME may possess some anti-estrogenic effects, at least in vitro. In another study in rats, PME’s robust antioxidant profile was hypothesized to increase androgenic activity via reducing oxygen radicals in the testes.\u003c\/p\u003e\n\u003cp\u003eThough PME lacks robust human data, the available literature suggests that this compound may possess some highly useful physiological effects.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhite Button Mushroom Extract (Agaricus blazei) (fruit) (30% polysaccharides)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eAgaricus blazei\u003c\/em\u003e, known commonly by a plethora of names – including button mushroom, white button mushroom, table mushroom, and champignon mushroom – is a small, edible mushroom endemic to North America and Europe. The most commonly consumed mushroom on the planet, commercial production and consumption of white button mushroom has existed since at least the early 18\u003csup\u003eth\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003ecentury, while indigenous oral records suggest the plant was consumed for centuries prior.\u003c\/p\u003e\n\u003cp\u003eRecent medical research has discovered that white button mushroom is a rich source of biologically-active compounds, including ergothioneine, an antioxidant with particularly potent free radical scavenging activity. Similar research has found that white button mushrooms – along with other varieties – possess unsaturated fatty acids such as linoleic acid, linolenic acid, and conjugated linoleic acid that may exert inhibitory activity on human aromatase, a cytochrome-P450 complex responsible for the conversion of testosterone into estrogen.\u003c\/p\u003e\n\u003cp\u003eIn two separate studies by similar researchers, both rats and human cell lines were fed and\/or incubated with various extract strengths and doses of white button mushroom extract. Both the animal experiments and “in-cell” aromatase assays demonstrated that WBME exerted powerful anti-aromatase effects, reducing total aromatase amounts and activity across all experimental conditions.\u003c\/p\u003e\n\u003cp\u003eThe most encouraging aspect of these studies is the servings of white button mushroom used in the experimental conditions: they are easily achievable through oral consumption, unlike many other plant-based, physiologically active compounds.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eL-Theanine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThough the literature surrounding L-theanine is still emerging, the amino acid is slowly building a reputation as one of the most interesting and exciting compounds being targeted for therapeutic use. L-theanine is an amino acid found almost exclusively in tea, constituting approximately 1-2% of the dry weight of tea – resulting in a 25–60 mg theanine load per 200 ml serving of liquid tea.\u003c\/p\u003e\n\u003cp\u003eFirst identified in green tea and in the mushroom\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eXerocomus badius\u003c\/em\u003e, L-theanine readily crosses the blood-brain barrier in a dose-dependent manner, and it is thought to influence the central nervous system (CNS) through a variety of mechanisms, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInhibiting glutamate reuptake and blockade of glutamate receptors in the hippocampus.\u003c\/li\u003e\n\u003cli\u003eIncreasing gamma-aminobutyric acid (GABA – a neurotransmitter associated with the regulation of responses) concentrations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIn addition to these more well-demonstrated effects, emerging electroencephalography trials on theanine suggest that the amino acid may exert a positive effect on alpha waves – a type of brain wave implicated in restful relaxation. Alpha activity has also been associated with increased creativity, increased performance under stress, and improved learning and concentration, as well as decreased anxiety.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e3,3'-Diindolylmethane (DIM)\u003cu\u003e\u003cbr\u003e\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhat we typically refer to as “Estrogen,” is in fact a group of three biologically distinct hormones – estradiol (E\u003csub\u003e2\u003c\/sub\u003e), estrone (E\u003csub\u003e1\u003c\/sub\u003e), and estriol (E\u003csub\u003e3\u003c\/sub\u003e), each possessing different activities in different cell, tissue, and receptor types. When experts refer to either the benefits or downfalls of “estrogen,\" they really mean to identify\u003cspan\u003e \u003c\/span\u003e\u003cem\u003ea specific\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eestrogen.\u003c\/p\u003e\n\u003cp\u003eThese\u003cspan\u003e \u003c\/span\u003e\u003cem\u003especific estrogens\u003c\/em\u003e, in turn, metabolize into even more specific estrogen sub-compounds, such as the 2-hydroxyestrogens (2-OHE’s), 2-methoxyestrogens, 16a-hydroxyestrone (16-OHE1), and 4-hydroxyestrogens (4-OHE’s). As their parent estrogens, these estrogen metabolites exert different effects depending upon the tissue and cell one is examining. In fact, two estrogen metabolites in particular, 16-OHE1 and 2-OHE, have such contrasting cellular activities that 2-OHE is an\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eestrogen antagonist.\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003eYes, that is correct: there is an anti-estrogen, estrogen.\u003c\/p\u003e\n\u003cp\u003eIn recent years, so-called phytonutrients have become the focus of clinical research, as these natural compounds have shown the ability to modulate the body’s estrogen ratio. One of these phytonutrients, is a dietary indole known as indole-3-carbinol (I3C). Unfortunately, despite its metabolic usefulness, I3C is highly molecularly unstable, and therefore unsuitable for use as a therapeutic agent or dietary supplement.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eN-Coumaroyldopamine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eN-Coumaroyldopamine is a natural analogue to the phytochemical N-Caffeoyldopamine, itself found prominently in various plants, including cocoa (Theobroma cacao L.). N-Coumaroyldopamine, its parent compounds, and other analogs that derive from its parent compound, have recently been the subject of phytochemical analyses due to their chemical similarity to sympathomimetic amines known to couple to the beta-2-adrenergic receptor.\u003c\/p\u003e\n\u003cp\u003ePhytochemical analyses were subsequently designed to assess the potency of N-Coumaroyldopamine and N-Caffeoyldopamine as beta-2-adrenergic receptor agonists – or, in simpler terms, their ability to “turn on” the fabled beta-2-adrenergic receptor. In these trials, the phytochemicals were shown to be as potent as several well-known beta-2-adrenergic receptor agonists (salbutamol, procaterol, and fenoterol). You read that correctly: N-Coumaroyldopamine and N-Caffeoyldopamine were found to bind as tightly to the beta-2-adrenergic receptor as well known synthetic compounds!\u003c\/p\u003e\n\u003cp\u003eThe desirability of activating the beta-2-adrenergic receptor arises due to the critical role that beta-2-adrenertic receptors play in both skeletal muscle and adipose metabolic function. In particular, beta-2-adrenergic receptors have been shown to induce dilation in the vasculature (vasodilation – the process involved in a “pump”), increase oxygen uptake and nutrient transport to skeletal muscle, regulate thermogenesis (the production of body heat), inhibit the pro-adipogenic effects of other adrenergic receptor types, as well as directly increase lipolysis and the oxidation of fatty acids.\u003c\/p\u003e\n\u003cp\u003eBeta-2-adrenergic receptors achieve these effects via one of the body’s key chemical messengers, known as cAMP (cyclic adenosine monophosphate). cAMP works as a sort of cell-type translator and foreman: it receives an input from, say, a receptor such as the beta-2-adrenergic receptor, and then communicates and directs the types of cells that the beta-2-adrenergic receptor would like to target.\u003c\/p\u003e\n\u003cp\u003eJust within the context of beta-2-adrenergic agonism, this amounts to cAMP increasing resting metabolic rate and caloric expenditure (the amount of calories you burn), improving peripheral sensitivity to glucose and glucose utilization, reduction of gluconeogenesis, induction of AMPk (adenosine monophosphate kinase) release, triggering of lipolysis, the inhibition of lipogenesis, and vasodilation.\u003c\/p\u003e\n\u003cp\u003eOr, in other words, cAMP is involved in nearly every beneficial physiological process that a lifter, runner, hiker, jumper, runner, tumbler, and fumbler would want. cAMP is involved in:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIncreasing bloodflow (“pump”).\u003c\/li\u003e\n\u003cli\u003eReducing muscle protein usage (catabolism).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTo say that cAMP is a desirable compound to increase the release of – which activating the beta-2-adrenergic receptor does – would qualify as the understatement of the year!\u003c\/p\u003e\n\u003cp\u003eLuckily, however, I3C readily metabolizes into the secondary indole 3,3’ diindolylmethane, or DIM for short. When used in a supplemental fashion in clinical trials, DIM appears to possess all the positive effects of its parent compound.\u003c\/p\u003e\n\u003cp\u003eDIM also exerts its own direct physiological effects, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAdjusting the activity of certain cytochrome enzymes, reducing the activity at the estrogen receptor site.\u003c\/li\u003e\n\u003cli\u003eLimit the cell division and growth of certain estrogens.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDespite the bodybuilding community’s single-minded crusade to eliminate estrogen wherever it lie in wait, compounds such as DIM show us that estrogen is a\u003cspan\u003e \u003c\/span\u003e\u003cem\u003every\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003ediverse set of compounds – and that we should actively pursue increasing certain estrogens that have beneficial, and ironically, anti-estrogenic effects.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"28 Servings \/ Black Lightning","offer_id":42901225996530,"sku":"coreexprdbl","price":49.95,"currency_code":"USD","in_stock":false},{"title":"28 Servings \/ Pineapple Strawberry","offer_id":42901226029298,"sku":"coreexprdps","price":49.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/hard-pinneapple-strawberry_1800x1800_7586e88a-489d-4ef7-8505-e146b2e89d84.png?v=1608343464"},{"product_id":"core-iso-whey-protein-isolate","title":"Core ISO Whey Protein Isolate","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eYour workout is the jungle. Whey isolate is the lion – its King.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCore ISO is, simply put, the pinnacle. Our protein’s quality, level of purity, and most importantly, gourmet taste, make drinking a shake your favorite and most effective part of your training day!\u003c\/p\u003e\n\u003cul class=\"ticks\" data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e1 scoop per serving.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e48 servings per container.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003ePurest protein available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIf the post-workout environment were a jungle, whey protein isolate (WPI) would be the lion – its king. Newer proteins enter into the market, receive fanfare and applause, and then inevitably fall out of favor. WPI, however, is the U.S. Dollar, Greenwich Mean Time, or Michael Jordan’s dunking prowess: it is the reference standard against which everything else is measured. The success or efficacy of all other proteins is gauged relative to what the one true king, WPI, has previously done.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSo, given WPI’s long-standing Elvis status, there is simply no way it could be improved on. Right? Wrong. Amino-filled and\/or spiked, low quality, low purity WPI formulas still run rampant on the market – robbing consumers of what they should be receiving, and exchanging the king for a jester.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThat has never been Core’s approach, and it never will be. With Core ISO, we have developed the purest, highest-quality, least-adulterated WPI product on the market. We have taken the highest purity, non-instantiated, non-soy, non-GMO whey protein isolate available, and essentially added nothing to it: we have added no sugars, making it the perfect versatile protein; and we have added no artificial colors, meaning you can feel good about drinking it.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eDid we mention we use natural flavoring? And Oh. My. Goodness, what flavoring it is! While the bitterness of WPI overcomes most brand’s offering, and results in a dull, palette-killing powder you need to choke down, Core ISO tastes like a gourmet pastry chef set up shop, on your tongue, and started making soufflés like nobody’s business.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCore ISO is, simply put, the pinnacle. Our protein’s quality and level of purity transcends it to the level of being a necessity; a part of your supplement and training setup that is simply assumed to be there, because it must be there. So, if you are already taking or planning to use protein, why not use the version of the standard that rises above the rest?\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"1.5 lbs \/ Frosted Cinnamon Roll","offer_id":48782397079794,"sku":"corenutraiso-fcs1.5","price":49.95,"currency_code":"USD","in_stock":false},{"title":"1.5 lbs \/ Frosted Vanilla Cupcake","offer_id":48782397702386,"sku":"corenutraiso-fvc1.5","price":49.95,"currency_code":"USD","in_stock":false},{"title":"1.5 lbs \/ Death by Chocolate","offer_id":48782397964530,"sku":"corenutraiso-dbc1.5","price":49.95,"currency_code":"USD","in_stock":true},{"title":"1.5 lbs \/ Strawberries n' Cream","offer_id":48782397735154,"sku":"corenutraiso-snc1.5","price":49.95,"currency_code":"USD","in_stock":true},{"title":"1.5 lbs \/ Chocolate Peanut Butter Cup","offer_id":48782397833458,"sku":"corenutraiso-cpbc1.5","price":49.95,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Frosted Cinnamon Roll","offer_id":38042899841204,"sku":"corenutraiso-1","price":49.95,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Chocolate Peanut Butter Cup","offer_id":38042899972276,"sku":"corenutraiso-5","price":42.46,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Red Velvet Cake","offer_id":38042899873972,"sku":"corenutraiso-2","price":49.95,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Lemon Cake","offer_id":43573591638258,"sku":"corenutraiso-10","price":49.95,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Strawberry Shortcake","offer_id":38042899906740,"sku":"corenutraiso-3","price":49.95,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Chocolate Decadence","offer_id":38042899939508,"sku":"corenutraiso-4","price":49.95,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Peanut Butter Toffee","offer_id":38042900005044,"sku":"corenutraiso-6","price":49.95,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Vanilla Cake","offer_id":38042900037812,"sku":"corenutraiso-7","price":49.95,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Chocolate Mint Cookie","offer_id":38042900070580,"sku":"corenutraiso-8","price":49.95,"currency_code":"USD","in_stock":false},{"title":"2 lbs \/ Cappuccino","offer_id":44648342257906,"sku":"corenutraiso-capp","price":42.46,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/ISO_FCB_FRONT_d963e3de-7aaf-4ef2-9142-7f60359bd412Large.jpg?v=1771804301"},{"product_id":"core-hard-leaning-agent","title":"Core Hard-Leaning Agent","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003ch2 style=\"text-align: center;\" data-mce-fragment=\"1\"\u003eCore Hard\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCore HARD is the pinnacle in recomposition supplementation. The ingredients in HARD have been specifically chosen to balance your hormonal environment and maximize your lean mass.\u003c\/p\u003e\n\u003cul class=\"ticks\" data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e3 capsules per serving.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e28 servings per container.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eBody recomposition.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eYour diet is impeccable and couldn’t be any more in check – macros, micros, you have it all down. Your workouts? Get out of here! You have slaved, grinded, and grunted your way through leg workouts so intense the gym staff cried – and those were on your worst days. And yet, something is missing.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIt’s that “extra” level of shred, “that look.” You know exactly what we mean. That type of leanness and density that makes an arm look twice as big, a stomach look twice as lean, and a forearm look like a roadmap for the Italian countryside. It’s that kind of elusive hardness that’s so rare, most of us simply chalk it up to genetics, or luck, or steroids, or whatever excuse we have handy – and yet we all still want it.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThe reality? It isn’t all that unattainable. Getting “that” look, “that” hardness, is about balance and recomposition. It’s a matter of adding in that final piece of the puzzle that makes the entire picture come out perfectly.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTo be hard, you need to get HARD. It’s that simple.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCore HARD is another product in the Core Nutritionals’ lineup to follow the basic, but indispensable principles that Core Nutritionals is slowly making an industry standard: create products with effective ingredients, in effective doses, in a non-proprietary formula. This time around, we have applied those principles to the problem of softness that we all despise and have developed the most advanced ultra-hardening and recomposition agent on the market.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTaking advantage of both the old and the new, Core Nutritionals has employed both modern, cutting-edge compounds and traditional herbs to create a balanced approach to delivering hardness. Key ingredients in Core HARD affect some of the body’s critical physiological pathways, combining sexiness and science in a single, non-proprietary formula. We have included five powerful ingredients into a full month's worth of stimulant free, recomposition goodness.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCore HARD can be used alone, or in a stack with other Core Nutritionals’ products. The BURN HARD stack (Core HARD plus Core BURN) will be the ultimate fat blasting and hardening stack. Men can try the HARD A.B.s stack (Core HARD plus Core ALPHA plus Core BURN) to help create that chiseled look that all men want.\u003c\/p\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003eHard Supp Facts\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePhosphatidylserine (50%)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePhosphatidylserine, colloquially known as PS, is a nearly ubiquitous phospholipid found in various membranous tissues throughout the body. PS’s ubiquity coincides with its necessity for crucial physiological functions, as the phospholipid is implicated in several components of cell communication, as well as the mediation of catecholamine synthesis and transmission in the brain (along with other neuroendocrine functions). In a fitness-related context, a nascent but growing body of methodologically-sound research suggests that PS may play a role in increasing exercise capacity.\u003c\/p\u003e\n\u003cp\u003eOverall, phosphatidylserine appears to play a valuable role in the increase in exercise capacity. PS may therefore play a critical role in the continued exercise success of bodybuilders in a, “cutting” or recomposition stage.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKSM-66® Full-spectrum Ashwagandha root extract (5% Withanolides)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eWithania somnifera Dunal\u003c\/em\u003e, colloquially known as Winter Cherry or Indian Ginseng, is an herb that features prominently in the traditional Indian medicinal system of Ayurveda. Known as Ashwagandha in Ayurveda,\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eWithania somnifera\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis a critical ingredient in various Ayurvedic tonics and tinctures prepared as a traditional remedy for the treatment of various ailments.\u003c\/p\u003e\n\u003cp\u003eRecently identified as a potent adaptogenic and target for therapeutic applications, Ashwaghanda has been the subject of numerous animal, pre-clinical, and clinical trials designed to examine its potential effects as an antioxidant, anti-carcinogenic, anxiolytic, antibacterial, antifungal, and immonumodulating compound. Ashwaghanda’s broad therapeutic potential is hypothesized to be the result of its robust phytochemical profile, including a wide swath of alkaloids, sitoindosides, and the highly biologically active withanolide group. As the principally biologically active compounds within Ashwaghanda, withanolides such as withanone, withaferine A, withanolides A, D, and G have been identified, isolated, and extensively studied in the various applications noted above.\u003c\/p\u003e\n\u003cp\u003eIn recognition of the potential physiological benefits of withanolides, Core Nutritionals selected KSM-66® to include in its HARD formula. KSM-66® is a full-spectrum Ashwaghanda extract, standardized for 5% withanolides – meaning that KSM-66® not only includes the full range of biologically active compounds within Ashwaghanda, but also that it contains the highest currently available concentration of the principally active withanolides (5%).\u003c\/p\u003e\n\u003cp\u003eThe high concentrations of withanolides within KSM-66® has resulted in encouraging results in a number of human, clinical trials – particularly considering many of these trials were conducted using the methodological gold standard of randomization, double-blind delivery, and placebo control. Amongst the most impressive results contained in these trials:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eA 27.9% reduction in serum cortisol levels, measured over 60 days in a trial featuring 64 chronically stressed adults.\u003c\/li\u003e\n\u003cli\u003eStatistically significant increases to endurance and stamina, as measured by VO2 max, in a clinical trial featuring 50 healthy, exercise-trained adults.\u003c\/li\u003e\n\u003cli\u003eIncreased measures of well-being as reported by self-assessment scales, included in both the clinical trials mentioned above.\u003c\/li\u003e\n\u003cli\u003eStatistically significant increases in serum testosterone levels in a clinical trial featuring 68 infertile men.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThough each of these results is impressive, perhaps the most significant is the 27.9% reduction in cortisol seen in the 60 day trial. As detailed above, cortisol possesses a multitude of potentially degradative physiological effects, including: inhibiting glucose uptake, causing a constriction of the vasculature (vasoconstriction), the breakdown of glycogen, and inarguably the result most would desire to avoid, proteolysis (the breakdown of muscle tissue).\u003c\/p\u003e\n\u003cp\u003eTo put it the simplest way possible, cortisol’s chief functions involve either turning on, or shutting off, the very things we as fitness enthusiasts want to avoid or turn on, respectively!\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCocoabuterol®\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCocoabuterol®, made up of the bioactive compounds found in cocoa, has been shown through studies and application to have beneficial factors on fat loss, muscle building, and insulin sensitivity. This caffeine free ingredient exhibits a mechanism of action in the body to increase cAMP (cyclic adenosine monophosphate) levels, which acts as a second messenger and regulator of many movements exhibited by all three types of cells in the human body. In this context, fat (adipose) tissue epinephrine utilizes cAMP to increase to triglyceride hydrolysis and cardiac (heart) muscle epinephrine utilizes it to increase contraction rate. This action can have positive benefits on body composition and performance.\u003c\/p\u003e\n\u003cp\u003eTheobromine, one of the main methylxanthine compounds found in cocoa is primarily effective in the increase of nitric oxide to in the blood stream, which is beneficial to produce the “pump” when ingested pre-workout. Another reaction that can be seen with theobromine is dilation of blood vessels. This can increase blood flow during vigorous exercise leading to increased time to exhaustion but also can pose benefits to individuals who suffer from high blood pressure. Theobromine also has a very high bioavailability and ability to stay in the body for extended periods of time (7-8 hours). Several studies have also looked at the effects of theobromine on human subjects and results have shown its ability to reduce oxidative stress on cells and regulation of gene expression.\u003c\/p\u003e\n\u003cp\u003eCocoabuterol® has also been shown to have positive benefits on reducing oxidative stress in the body. Due to its rich antioxidant properties, it has the ability to fight off free radicals that can be detrimental. In addition to this, the polyphenols that Cocoabuterol® contains have been shown to reduce inflammatory signals within the body that can also be detrimental biomarkers.\u003c\/p\u003e\n\u003cp\u003eBy now you have read some of the amazing benefits of Cocoabuterol® and why we have included in this recomposition agent. When your goal is maintaining muscle mass, shedding body fat, reducing overall stress, and performing at your peak, we make sure you are equipped with the right ingredients, in the right dosages, and for the right purpose. In summary, Cocoabuterol® does all of these things by:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eIncreasing power output due to elevated NO production via theobromine effects.\u003c\/li\u003e\n\u003cli\u003eIncreasing adipose usage through cAMP action in the body.\u003c\/li\u003e\n\u003cli\u003eImproving senses of well-being due to high levels of polyphenols and antioxidants reducing overall stress on the body from workouts and life events.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e3,3'-Diindolylmethane (DIM)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhat we typically refer to as “Estrogen,” is in fact a group of three biologically distinct hormones – estradiol (E2), estrone (E1), and estriol (E3), each possessing different activities in different cell, tissue, and receptor types. When experts refer to either the benefits or downfalls of “estrogen,\" they really mean to (but probably cannot) identify\u003cspan\u003e \u003c\/span\u003e\u003cem\u003ea specific\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eestrogen.\u003c\/p\u003e\n\u003cp\u003eThese\u003cspan\u003e \u003c\/span\u003e\u003cem\u003especific estrogens\u003c\/em\u003e, in turn, metabolize into even more specific estrogen sub-compounds, such as the 2-hydroxyestrogens (2-OHE’s), 2-methoxyestrogens, 16a-hydroxyestrone (16-OHE1), and 4-hydroxyestrogens (4-OHE’s). As their parent estrogens, these estrogen metabolites exert different effects depending upon the tissue and cell one is examining. In fact, two estrogen metabolites in particular, 16-OHE1 and 2-OHE, have such contrasting cellular activities that 2-OHE is an\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eestrogen antagonist\u003c\/em\u003e. Yes, that is correct: there is an anti-estrogen, estrogen.\u003c\/p\u003e\n\u003cp\u003eIn recent years, so-called “phytonutrients” have become the focus of clinical research, as these natural compounds have shown the ability to increase the ratio of good, estrogen decreasing estrogens (such as 2-OHE), to bad, estrogen increasing estrogens (such as 16-OHE1). One of these phytonutrients, a dietary indole known as indole-3-carbinol (I3C), is the bioactive phytochemical and a presumed modulator of reduced cancer risk in areas with high cruciferous vegetable consumption. Unfortunately, despite its potent antiestrogenic activity, I3C is highly molecularly unstable, and therefore unsuitable for use as a therapeutic agent or dietary supplement.\u003c\/p\u003e\n\u003cp\u003eLuckily, however, I3C readily metabolizes into the secondary indole 3,3’ diindolylmethane, or DIM for short. When used in a supplemental fashion in clinical trials, DIM appears to possess all the positive effects of its parent compound with respect to antiestrogenic action – promoting the metabolism of beneficial estrogens that themselves reduce estrogenic activity.\u003c\/p\u003e\n\u003cp\u003eAside from its healthy-estrogen promoting abilities, DIM also exerts its own direct physiological effects, including:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003ePromoting pathways of internal estrogen metabolism that favour the production of anti-estrogen estrogens.\u003c\/li\u003e\n\u003cli\u003eAdjusting the activity of certain cytochrome enzymes, reducing the activity at the estrogen receptor site.\u003c\/li\u003e\n\u003cli\u003eLimit the cell division and growth of certain estrogens.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDespite the bodybuilding community’s single-minded crusade to eliminate estrogen wherever it lie in wait, compounds such as DIM show us that estrogen is a very diverse set of compounds – and that we should actively pursue increasing certain estrogens that have beneficial, and ironically, anti-estrogenic effects\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eL-Theanine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThough the literature surrounding L-theanine is still emerging, the amino acid is slowly building a reputation as one of the most interesting and exciting compounds being targeted for therapeutic use. L-theanine is an amino acid found almost exclusively in tea, constituting approximately 1-2% of the dry weight of tea – resulting in a 25–60 mg theanine load per 200 ml serving of liquid tea.\u003c\/p\u003e\n\u003cp\u003eFirst identified in green tea and in the mushroom\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eXerocomus badius\u003c\/em\u003e, L-theanine readily crosses the blood-brain barrier in a dose-dependent manner, and it is thought to influence the central nervous system (CNS) through a variety of mechanisms, including:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eIncreasing the release and concentration of dopamine.\u003c\/li\u003e\n\u003cli\u003eInhibiting glutamate reuptake and blockade of glutamate receptors in the hippocampus.\u003c\/li\u003e\n\u003cli\u003eIncreasing gamma-aminobutyric acid (GABA – a neurotransmitter associated with the regulation of responses) concentrations.\u003c\/li\u003e\n\u003cli\u003eIncreasing levels of serotonin.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIn addition to these more well-demonstrated effects, emerging electroencephalography trials on theanine suggest that the amino acid may exert a positive effect on alpha waves – a type of brain wave implicated in restful relaxation. Alpha activity has also been associated with increased creativity, increased performance under stress, and improved learning and concentration, as well as decreased anxiety.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":39522918334644,"sku":"corehardrecomppill","price":44.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/Core-Hard_1800x1800_a033b4ed-3267-4c18-8a69-6cf6eed7e2da.jpg?v=1617322882"},{"product_id":"core-sear-non-stim-thermo","title":"Core SEAR Non Stim Thermo","description":"\u003ch2 data-mce-fragment=\"1\" style=\"text-align: center;\"\u003eCore SEAR Stim Free Thermogenic\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eWhy do we call it “burning fat”? It is a strange turn of phrase, as the body does not “burn” the adipose tissue (the technical name for “fat”). Of course, heat is involved in the base process of fat metabolism, hydrolysis, but the average person of course does not have this in mind. What the common phrasing captures is that the adipose tissue is now being used for fuel – burned up, as gasoline is burned up in a combustion engine as fuel for the vehicle. In this sense, the phrase “burning fat” captures something essential about the mechanisms of adipose metabolism. One mechanism of increasing this process overall is increasing the conversion of WAT (white adipose tissue) to BAT (brown adipose tissue) – known as the “browning” of fat.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/nonstimfatburner_480x480.jpg?v=1667109303\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIt is precisely this mechanism that Core SEAR affects. There are many pathways to enhance lipolysis, the process by which stored triglycerides – the “stuff” of fat tissue – are broken down to release their potential energy into actual energy. One of the most effective is modulating the enzymes that interconvert WAT (white adipose tissue, which stores energy) to BAT (brown adipose tissue, which releases energy) and the chemical and enzymatic cascades that induce lipolysis. SEAR addresses both. Sinetrol XPur®, a blend of citrus fruit extracts, and MitoBurn™, a metabolite of L-valine, have been demonstrated to increase white-to-brown adipose tissue conversion and therefore the resultant energy expenditure increase. Meanwhile, Coleus forskholli and Paradoxine® have been shown to heavily influence cellular communication and enzymatic pathways involved in lipolysis, specifically the cAMP and AMPk pathways.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTogether, this simple but incredibly powerful formula earns its name: searing white into brown adipose tissue and increasing your body’s energy expenditure due to fat metabolism.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":39523094364340,"sku":"coresearpills","price":44.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/SEAR_1800x1800_c059fe1b-347f-4112-9468-464733baf2fb.jpg?v=1759475626"},{"product_id":"poise-female-hormone-support","title":"Poise Female Hormone Support","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003ch2 style=\"text-align: center;\" data-mce-fragment=\"1\"\u003ePoise Female Hormone Support\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eNot every supplement is about “the gains.” While the sports nutrition and performance space, as the name implies, justifiably focuses on supplements that maximize athletic performance, too often the space neglects imperatives outside the gym. That is, the space ignores that we all exist outside the gym, at home and in the workplace, and have supplemental needs in these spaces too – to help us respond to and optimize our daily lives. This is especially true for women, who are too often marketed only “weight loss” supplements, ignoring that women have extensive physiological needs.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eAnd let’s face it: modern life only exacerbates these needs. Environmental stressors, work, inconsistent diet, and poor sleep habits all contribute to a lifestyle deleterious to the homeostasis of key bodily systems. Chief among them, the complex endocrine pathway that regulates the synthesis, distribution, and uptake of hormones. It is becoming increasingly hard to maintain the healthy and normal hormonal homeostasis that allows us to perform optimally in the gym and workplace. This is especially true for women.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCore POISE is a unique and specifically formulated solution to this problem. Our tailored ingredient profile addresses the mechanisms associated with the body’s stress response. Key ingredients such as magnesium, DIM, Chaste berry, and pregnenolone, are all heavily involved in sex hormone biosynthesis and estrogen balance, and some have been demonstrated to mitigate some of the discomfort associated with PMS. Other ingredients, such as iodine, turmeric extract and Olea europaea help optimize your body’s response to stress, providing and supporting thyroid health. Stress impact on the thyroid can lead to a suppressed metabolism, which can lead to unwanted weight gain. So, while POISE will not make your life easier, it certainly makes responding to it easier.\u003c\/p\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003ePoise Supp Facts\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eMagnesium (as Magnesium Bisglycinate Chelate (TRAACS™):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIt is difficult to overstate the biological necessity of magnesium. Magnesium is a co-factor in over 300 enzymatic reactions that regulate essential physiological functions such as protein synthesis, glucose homeostasis, muscle and nerve function, and the maintenance and support of healthy blood pressure levels.\u003c\/p\u003e\n\u003cp\u003eIn addition to these benefits, magnesium (especially Magnesium Bisglycinate Chelate) has been studied for its benefits in reducing dysmenorrhea (menstrual cramps) through its ability to relax the smooth muscle of the uterus and reduce the prostaglandins that cause painful cramps. Magnesium levels also tend to fluctuate during a menstrual cycle. During the second half of a cycle when estrogen and progesterone are higher, magnesium levels tend to drop even more. Supplementation with a high-quality magnesium can assist in maintaining an optimal level.\u003c\/p\u003e\n\u003cp\u003eMagnesium’s influence on the thyroid is also of importance. Magnesium is responsible not only for making the inactive T4 (thyroxine) in the thyroid gland but also for converting T4 into the active form of T3 (triiodothyronine). This is important because the metabolism of your body’s cells is enhanced by T3 specifically. These two hormones have a large influence on metabolic rate, heart and digestive function, muscle control, brain development and bone maintenance. Studies have shown that severely low serum magnesium can be associated with an increased risk of anti-thyroglobulin antibodies, which can be a sign of thyroid gland damage caused by the immune system. It has also shown an increased risk of Hashimoto thyroiditis and hypothyroidism, two common autoimmune disorders.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIodine:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIodine is a trace element naturally present in certain foods, including kelp. Iodine is a critical component for fetal development, especially during early pregnancy, as maternal T4 (thyroxine) is the sole source of fetal thyroid hormone. After birth, especially if breast-feeding, iodine remains an important constituent of a balanced-diet to maintain adequate T3 (triiodothyronine) and T4 (thyroxine) levels in the mother and for proper cognitive development in the child.\u003c\/p\u003e\n\u003cp\u003eAs implied, however, the most important of iodine’s functions is assisting the body’s production and maintenance of both thyroid hormones and TSH (thyroid stimulating hormone, released by the pituitary). The thyroid hormones, in turn, regulate several critical biochemical reactions, including protein synthesis, and, along with norepinephrine\/epinephrine, largely determine the body’s metabolic rate.\u003c\/p\u003e\n\u003cp\u003eIn addition to these benefits for the thyroid, iodine can also be a critical element for women’s health. About 70% of the body’s iodine is concentrated in the tissues of the brain, immune system, ovaries, uterus, breasts, and prostate gland (in men). Being this close to the female reproductive system, iodine also has a large effect on ovulation and estrogen. Iodine is believed to reduce ovulation pain, prevent ovarian cysts, and boost progesterone levels when there is too much estrogen present, which can cause heavy menstruation, breast pain, fibroids, and premenstrual irritability. Iodine can also help reduce estrogen related side effects in two ways: by promoting healthy detoxification of estrogen and by making cells less sensitive to estrogen.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eL-Tyrosine:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTyrosine is amongst a class of amino acids known as ‘non-essential’ amino acids, so called because the body can produce them endogenously, and it is therefore not essential through dietary means. That being said, tyrosine is also what is known as a conditionally-essential amino acid; conditionally-essential because, along with glucose and ammonia, the synthesis of tyrosine additionally requires adequate levels of phenylalanine. Once synthesized, tyrosine is one of the most critical amino acids, given its prominent role as a substrate in the synthesis of the catecholamines dopamine, norepinephrine, and epinephrine, in addition to both T3 (triiodothyronine) and T4 (thyroxine) thyroid hormones.\u003c\/p\u003e\n\u003cp\u003eThyroid hormones are in fact derivatives of tyrosine that are bound covalently to iodine, meaning that tyrosine (as well as iodine) needs to be present in order for thyroid hormones to be produced. This supplementation can boost thyroid hormones levels in those who may have suppressed thyroid hormones levels. (It is important to note, however, that individuals who are already being prescribed thyroid medications or have an overactive thyroid should be cautious when supplementing with tyrosine and should seek the guidance of a healthcare professional prior to supplementing).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTurmeric Extract (Curcuma longa) (root) (95% curcuminoids):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCurcumin, the primary curcuminoid found in turmeric (a root known for its spice), has been the basis of many clinical studies for its therapeutic properties and ability to modulate multiple cells signaling pathways in certain inflammatory diseases known to humans.\u003c\/p\u003e\n\u003cp\u003eNumerous studies seem to suggest that curcumin powerfully inhibits the enzymes that synthesize inflammatory compounds such as prostaglandins and leukotrienes. In particular, basic research and molecular studies have now firmly established curcumin’s ability to dose-dependently and potently inhibit a transcription factor known as NF–kB – a molecule involved in the proliferation of pro-inflammatory cytokines, soft tissue destruction, and autoimmune responses. In relation to autoimmune conditions, Hashimoto’s thyroiditis is one in particular that is considered the leading cause of hypothyroidism. The overabundance of chronic inflammation found in the thyroid during these conditions can lead to less production of thyroid hormone all together, thus leading to a generalized slowing of a person’s metabolism.\u003c\/p\u003e\n\u003cp\u003eTurmeric can also have a positive impact on PMS related symptoms. This is seen primarily through the increased neurotransmitter release and inflammatory response associated with pre-menstrual occurrences. Many of the mood and behavior changes associated with PMS can be traced to neurotransmitter changes such as decreased norepinephrine, dopamine, and serotonin. These changes can be subject to the decline in estrogen and progesterone during this period. Turmeric has been shown in studies to increase these neurotransmitters, thus impacting these symptoms in a positive way. The increased inflammatory response due to the PMS period as well can be mitigated in the presence of turmeric due to its high anti-inflammatory benefits.\u003c\/p\u003e\n\u003cp\u003eStudies have shown that low quality curcumin has low bioavailability and benefit, which is why we have used a high standard curcumin with 95% curcuminoids and have also included the trademarked Bioperine® in this formula. These two ingredients have a largely cohesive impact that can drastically improve the health benefit. Studies have shown that Bioperine® significantly improved curcumin uptake by upwards of 2000% at doses that proved to be clinically beneficial.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOlive Extract (Olea europaea) (leaf) (20% Oleuropein):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUsing products derived from the olive tree for the basis of benefitting human health dates back several centuries. There has been a good body of research done lately on the benefits of olives and its derivatives. The polyphenols found in olives (and unrefined virgin olive oil) contain highly potent antioxidant and free radical fighting properties, making them highly sought out for their anti-inflammatory and immune boosting benefits. As we have discussed in subsequent ingredients and their benefits, these anti-inflammatory and immune boosting benefits include the positive impacts made towards thyroid health and PMS. Oleuropein is the most potent polyphenol found in olives (our source of olives contains 20%) and exhibits a very high antioxidant effect on the body through different mechanisms, resulting in an enhanced antioxidant response. This potential is mainly related to its ability to improve radical stability through the formation of intramolecular hydrogen bonds. Oleuropein may also be able to counteract oxidative stress and has shown in vitro to have a protective effect on lipid oxidation. As mentioned above, olive-derived phenolic compounds, including oleuropein, can have a beneficial anti-inflammatory effect. These compounds can decrease concentrations of pro-inflammatory agents that stimulate more inflammation in several different pathologies. It has been studied that oleuropein is able to elicit protective effects on modulating parameters of inflammation and other oxidative stressors.\u003c\/p\u003e\n\u003cp\u003eOleuropein has also been seen is studies to have positive impacts on thyroid conditions, in particular hypothyroidism (underactive thyroid), where the thyroid underproduces thyroxine and and overproduces Thyroid Stimulating Hormone (TSH). This high level of TSH can be expressed from the pituitary gland secreting excess amounts of TSH to stimulate the thyroid gland to produce more thyroid hormone in an attempt to balance secretions. Olive leaf supplementation has been shown to positively impact the thyroid this by promoting a lowering of TSH levels and increasing T3 (triiodothyronine) levels in an attempt to normalize thyroid function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChaste Tree Extract (Vitex agnus-castus) (fruit) (1.5% Agnusides)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eChaste Tree Berry, also known as Vitex agnus castus (VAC), is a shrub that is native to both Mediterranean Europe and Central Asia. Clinical reviews have supported the use of VAC as a remedy for many female conditions, including menstrual disorders (amenorrhea, dysmenorrhea), premenstrual syndrome (PMS), corpus luteum insufficiency, hyperprolactinemia, infertility, acne, menopause, and disrupted lactation. Chaste Berry exhibits a mechanism of action that increases dopamine activity in the brain, which results in a reduction of prolactin release in the body. When there is an increase in prolactin it can cause disturbances in a women’s menstrual cycle as well as deficiency in their levels of estrogen and progesterone. A prospective, multicenter trial in the efficacy of VAC on PMS was investigated in 50 patients. The Moos’ menstrual distress questionnaire (MMDQ) was the primary parameter and self-assessment was the second parameter. The inclusion of VAC showed that PMS-related symptoms were reduced but then gradually returned after cessation of the trial period. Studies such as this one show that using VAC as a remedy for the symptoms associated with PMS can show clear improvements but should mainly be used for symptomatic relief rather than relief for the duration of the syndrome.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSetria® L-Glutathione:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePMS is often a high stress event for an individual. The overabundance of estrogen compared to progesterone can increase overall stress. When cortisol is not controlled, it can further lower progesterone, further dividing the needed balance between these two complimentary hormones. Glutathione is an amino acid containing molecule of L-glutamic acid, L-cysteine, and Glycine. It is vital to many different properties and is best known for being a powerful antioxidant. The ‘glutathione system’ comprises the enzymes that synthesize glutathione within a cell as dedicated enzymes that use glutathione for its antioxidant effects. Glutathione supplementation is thought to support this pool of glutathione present in cells and thus maintain the efficacy of the entire system. Free radicals can be a byproduct of many different things such as exercising, eating, and breathing to name a few. When these molecules overcome the body at the cellular level, this constant barrage can have negative impacts on health and overall wellness. This barrage can also include the stresses that one’s body might endure during pre-menstruation. Setria® L-Glutathione provides a potent supply of antioxidants that bind these free radicals, which can help keep them from causing lasting damage. Glutathione not only has the ability to neutralize free radicals, but it also can reactivate other antioxidants, such as Vitamin C and Vitamin E. Once these vitamins and their antioxidants do their job of neutralizing free radicals, they become unstable radicals themselves. Glutathione can help recycle these unstable molecules back to their antioxidant rich properties.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e3,3'-Diindolylmethane (DIM):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhat we typically refer to as “Estrogen,” is in fact a group of three biologically distinct hormones – estradiol (E2), estrone (E1), and estriol (E3), each possessing different activities in different cell, tissue, and receptor types. When experts refer to either the benefits or downfalls of “estrogen,\" they really mean to (but probably cannot) identify a\u003cspan\u003e \u003c\/span\u003e\u003cem\u003especific\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eestrogen.\u003c\/p\u003e\n\u003cp\u003eThese\u003cspan\u003e \u003c\/span\u003e\u003cem\u003especific\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eestrogens, in turn, metabolize into even more specific estrogen sub-compounds, such as the 2-hydroxyestrogens (2-OHE’s), 2-methoxyestrogens, 16a-hydroxyestrone (16-OHE1), and 4-hydroxyestrogens (4-OHE’s). As their parent estrogens, these estrogen metabolites exert different effects depending upon the tissue and cell one is examining. In fact, two estrogen metabolites in particular, 16-OHE1 and 2-OHE, have such contrasting cellular activities that 2-OHE is an estrogen antagonist. Yes, that is correct: there is an anti-estrogen, estrogen.\u003c\/p\u003e\n\u003cp\u003eIn recent years, so-called “phytonutrients” have become the focus of clinical research, as these natural compounds have shown the ability to increase the ratio of good, estrogen decreasing estrogens (such as 2-OHE), to bad, estrogen increasing estrogens (such as 16-OHE1). One of these phytonutrients, a dietary indole known as indole-3-carbinol (I3C), is the bioactive phytochemical and a presumed modulator of reduced cancer risk in areas with high cruciferous vegetable consumption. Unfortunately, despite its potent antiestrogenic activity, I3C is highly molecularly unstable, and therefore unsuitable for use as a therapeutic agent or dietary supplement.\u003c\/p\u003e\n\u003cp\u003eLuckily, however, I3C readily metabolizes into the secondary indole 3,3’ diindolylmethane, or DIM for short. When used in a supplemental fashion in clinical trials, DIM appears to possess all the positive effects of its parent compound with respect to antiestrogenic action – promoting the metabolism of beneficial estrogens that themselves reduce estrogenic activity.\u003c\/p\u003e\n\u003cp\u003eAside from its healthy-estrogen promoting abilities, DIM also exerts its own direct physiological effects, including:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003ePromoting pathways of internal estrogen metabolism that favor the production of anti-estrogen estrogens.\u003c\/li\u003e\n\u003cli\u003eAdjusting the activity of certain cytochrome enzymes, reducing the activity at the estrogen receptor site.\u003c\/li\u003e\n\u003cli\u003eLimit the cell division and growth of certain estrogens.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDespite the bodybuilding community’s single-minded crusade to eliminate estrogen wherever it lie in wait, compounds such as DIM show us that estrogen is a very diverse set of compounds – and that we should actively pursue increasing certain estrogens that have beneficial, and ironically, anti-estrogenic effects\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePregnenolone:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePregnenolone, or pregn-5-en-3β-ol-20-one, is known as the grandmother hormone due to its precursor role in the endogenous biosynthesis of most steroid hormones as well as others, including progesterone and estrogen. Pregnenolone also has a high relationship in the balancing of beta-estradiol and progesterone, which can have a positive impact on the distressing of symptoms associated with PMS, including menopausal depression. When pregnenolone levels are low, whether it be due to high amounts of oxidative stress, increased cortisol, etc. it can have a negative impact on other bodily functions that are governed by hormones. When women in particular have low progesterone during their monthly cycle, it can lead to heavy menstruation and increased levels of estrogen, which can decrease sex drive and increase weight gain. Pregnenolone needs to be present in order for the balance of progesterone and estrogen to occur. This balance of hormones can thus lead to more balance during the menstruation period and lower the severity of PMS symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBioperine® (95% Black Pepper Extract):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBioPerine® is a patented standardized extract from the fruit of Piper nigrum (black pepper). It’s studied benefits have shown improvements in bioavailability of nutrients it is surrounded by. In this specific product for Core POISE, it is included because it dramatically increases the bioavailability of curcuminoids (see above). Without Bioperine, the serum concentration and absorption rates of the active agents in curcumin would be significantly reduced.\u003c\/p\u003e\n\u003cp\u003eBioPerine® primarily works through mechanisms and channels that can inhibit intestinal motility and dilate blood vessels of the intestines (where absorption of nutrients occurs). This physiological action may cause increased absorption and digestion of nutrients.\u003c\/p\u003e\n\u003cp\u003eSeveral studies looking at the impact of BioPerine® on nutrient absorption have been done. One study looking at the efficacy of BioPerine® on serum concentrations of curcumin showed bioavailability was improved by more than 500%. Therapeutic effectiveness of curcumin has often been exhibited as low. Another study conducted over the course of 6 weeks on BioPerine® influence on serum selenium levels in humans showed an increase by 145% over the presupplementation value.\u003c\/p\u003e\n\u003cp\u003eWith promising research being done on the effects of BioPerine® in the context of nutrient absorption and bioavailability, it is only fitting that we include it in Core POISE.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":39523184279732,"sku":"corepoisefemalesupt","price":39.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/corepoise.jpg?v=1617327726"},{"product_id":"blaze-thermogenic","title":"Core Blaze Thermogenic","description":"\u003ch2 style=\"text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan data-mce-fragment=\"1\"\u003eCore BLAZE Multi-Stage Thermogenic\u003c\/span\u003e\n\u003c\/h2\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eThis is formulated to drop the kitchen sink and “miracle” ingredient tactics, and instead uses a diverse range of scientifically proven ingredients to create a powerful, balanced, and effective product. Core BLAZE is designed to target precise primary and secondary metabolic pathways, at multiple targets, to ensure maximum effectiveness. No more playing darts in the dark when it comes to weight management categories; randomly including ingredients, in whatever servings, hoping that something works. Specific and multi-targeted. These words exemplify the new, must needed approach. Amazing ingredients, in clinically-reflected serving sizes, all included in a non-proprietary blend so you know exactly what you’re consuming to incinerate fat stores and reach your body composition goals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/normalstimfatburner_480x480.jpg?v=1667106657\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan data-mce-fragment=\"1\"\u003eCore Blaze Supp Facts\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBlack Cumin Seed Powder\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBlack cumin, also known as Nigella sativa, is a plant that has been touted for its medicinal benefits that target relief from abdominal pain, dyslipidemia, asthma, headache, inflammation, obesity, and hypertension, amongst other things. One study in particular using Nigella sativa as a complementary factor in obesity management, along with proper diet and exercise, was shown to reduce body weight and BMI. Waist circumference was not statistically significant but more research is needed to look at other anthropometric benefits.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcetyl L-Carnitine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eL-carnitine is a derivative of the amino acid lysine and, as certain conditions outpace the body’s ability to produce it, l-carnitine is considered a conditionally essential amino acid. While endogenous biosynthesis of l-carnitine from the amino acids lysine and methionine is sufficient for essential processes – along with dietary sources of carnitine from protein-rich red meat, for example – dietary supplementation of carnitine may pose benefits in certain physiological conditions.\u003c\/p\u003e\n\u003cp\u003eUnfortunately, due to excess metabolism of l-carnitine by microorganisms in the small intestine, exogenous supplementation with oral l-carnitine has proved ineffective. ALCAR, an acetylated version of l-carnitine, has considerably higher oral bioavailability, due likely to only partial hydrolytic metabolism. Once in the bloodstream, ALCAR plays a fundamental role in the production of energy, acting as the catalyst for the beta-oxidation of long chain fatty acids by the mitochondria; regulating the CoA to Acyl-CoA ratio (necessary for the production of ATP); and the metabolism of carbohydrates. ALCAR also is an excitatory agent for neurons, increases neuronal transmission, and increases the production of neurotransmitters and neurohormones such as dopamine and serotonin.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSchisandra Extract (9% Schisandrins)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eSchisandra chinesis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis a plant that has been studied to have beneficial health effects. Among these benefits include anti-cancer effects as well as antimicrobial effects against pathogens. In relation to metabolic benefits, studies have shown diets rich in Schisandra can improve pancreatic functions, stimulate insulin secretion, and reduce diabetic complications. Where Schisandra’s body composition benefits lie is in its proposed ability to prevent lipid accumulation and differentiation of preadipocytes to adipocytes. This process, known as adipogenesis is characterized by the ability of adipocytes to accumulating triglycerides in cytosolic lipid droplets, which are reservoirs for energy storage. Schisandrin has shown its ability to reduce lipid content, as well as increase acid oxidation and lipolysis. This process was shown to occur through the activation of protein kinase A and hormone sensitive lipase in the adipocytes of rats. In vivo, Schisandrin was shown to reduce subcutaneous adipocyte size, tissue mass, as well as body weight in mice.\u003c\/p\u003e\n\u003cp\u003eThe major regulator of this adipogenesis is peroxisome proliferator-activated receptor gamma (PPAR-γ). This specific receptor activates genes that stimulate lipid uptake and the generation of new adipocytes. Insulin sensitizers act as agonizer, which are able to increase triglyceride storage in adipose tissue by increasing insulin-stimulated glucose uptake. Schisandrin and its specific lignans were shown to prevent lipid accumulation and the differentiation of adipocytes through the mechanism of downregulating the key adipocyte regulatory genes PPAR-γ and others associated with such. These results are promising as a possible intervention in combatting weight gain.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCaulerpa Okamurae (50% Sodium Alginate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSeaweeds and other marine algae are a broad species that have often been considered a potential source for combating obesity and aiding in weight loss. Seaweeds in particular possess certain bioactive compounds that have the fat fighting agents with high potential. Fucoxanthin, alginates, fucoidans, and phlorotannins are these specific compounds. These compounds exhibit a mechanism of action that include the inhibition of lipid absorption and metabolism (fucoxanthin and fucoidans), the inhibition of adipocyte differentiation (fucoxanthin), and the effect on feelings of satiety (alginates). Caulerpa Okamurae is a specific seaweed, and in this case for Core BURN, we wanted to include a source that included 50% sodium alginates, which we just learned that alginates especially contribute to feelings of fullness. Caulerpa Okamurae has been shown in studies to reduce obesity-mediated inflammation, improve glucose metabolism, and increase insulin sensitivity. Studies have also shown Caulerpa Okamurae to have the ability to inhibit lipid accumulation and reduce the expression of the master regulator of adipogenesis. One study in particular done on high fat fed mice showed that with the administration of Caulerpa Okamurae, markers of weight gain such as free fatty acids, triglycerides, total cholesterol, glucose, and plasma insulin were reduced significantly.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCaffeine Anhydrous\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCaffeine is one of the most widely consumed, and perhaps one of the most reviewed, psychoactive compounds. Its physiological effects in a range of areas have been well-documented, including exercise performance, information processing, alertness and mood enhancement, attention, and awareness, along with its anti-lipogenic and lipolytic abilities.\u003c\/p\u003e\n\u003cp\u003eMost importantly to Core BLAZE, caffeine has been shown to have significant effects on exercise performance, even with ingestion in servings as small 3 to 9mg\/kg\/bw\/day (the equivalent of 2 cups of standard coffee, for a 170lb male). In endurance training, possible explanations for caffeine’s performance-enhancing effects lie in its metabolic effects on both lean and fat tissue. It is suggested that caffeine’s potent lipolytic (the breakdown of fat tissue into fatty acids) and oxidative (the actual ‘burning’ of fat) action allow the body to utilize these sources during prolonged submaximal exercise. As a consequence, muscle glycogen is spared and available for use later in the training session. Practically speaking, this means caffeine is forcing your body to preferentially use fat tissue as a fuel source, while sparing the glycogen which gives you the full-bodied look!\u003c\/p\u003e\n\u003cp\u003eIn short-term exercise, caffeine’s demonstrated role in the inhibition of cyclic AMP- phosphodiesterases (PDE), adenosine receptor antagonism, and adrenoreceptor agonism come into play. These three pathways collectively stimulate lipolytic activity, boost fat metabolism, increase metabolic rate and energy expenditure, and regulate the body’s thermogenic activity. The practical results of activating these pathways are increases to the contractile force of both cardiac and skeletal muscle (harder flexion), an increase in energy expenditure (freeing up more caloric energy to be used in contraction), dilation of vasculature (better blood flow), and improvements to both nitrogen retention and skeletal muscle protein synthesis (key components to muscle building).\u003c\/p\u003e\n\u003cp\u003eIn Core BLAZE, we have included a per-serving amount of caffeine that is neither excessive, nor arbitrary, but that instead reflects the servings used in clinical research.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBacopa Monniera (50% Bacopasides)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBacopa monnieri (BM), also known as the water hyssop commonly, or as Brahmi in Ayurvedic texts, is a small creeping herb endemic to sub-tropical India. The herb has been used in traditional Indian medicine for well over one thousand years, with its first recorded usage coming in the 6th century A.D. In this traditional context, BM has been used for a wide-range of purposes, including as a treatment of asthma and epilepsy.\u003c\/p\u003e\n\u003cp\u003eMore recently, BM has been the subject of numerous cognition and memory trials, as the plant has a well-established nootropic effect. Likely through modulation of the serotonin reuptake system, clinical trials in healthy human beings have demonstrated that BM possesses a significant effect on the retention of newly-learned information. In several trials utilizing a 300mg daily serving, BM was also shown to decrease the recall delay of newly learned information and reduce short term forgetfulness – suggesting that the herb’s effect on the serotonic and cholinergic systems are increasing the encoding (the literal storing) of memory information.\u003c\/p\u003e\n\u003cp\u003eBeyond cognition and memory encoding, BM has also been demonstrated to function as a potent adaptogen and relaxant – which in the Core BLAZE formula may help to smooth the effect curve of the product’s stimulants, reducing jitteriness or “crash.”\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTheobromine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTheobromine, one of the main methylxanthine compounds found in cocoa is primarily effective in the increase of nitric oxide to in the blood stream, which is beneficial to produce the “pump” when ingested pre-workout. Another reaction that can be seen with theobromine is dilation of blood vessels. This can increase blood flow during vigorous exercise leading to increased time to exhaustion but also can pose benefits to individuals who suffer from high blood pressure. Theobromine also has a very high bioavailability and ability to stay in the body for extended periods of time (7-8 hours). Several studies have also looked at the effects of theobromine on human subjects and results have shown its ability to reduce oxidative stress on cells and regulation of gene expression.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGlucovantage®\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGlucovantage® is a sustained release dihydroberberine, which is a highly bioavailable derivative of berberine. Once absorbed in the intestines, dihydroberberine rapidly converts to berberine in the blood and has been shown to be up to 5x more bioavailable than standard berberine. The benefits of berberine have been extensively studied for its positive effects on glucose balance, lipid metabolism, and overall blood vessel health. In fact, berberine is one of the leading compounds that is used to increase insulin sensitivity, or how well your body responds to insulin. Glucose uptake to tissues is influenced by berberines ability to activate the adenosine monophosphate kinase (AMPK) pathway, which plays an important role in energy balance regulation. Results from pre-clinical studies indicate berberine promotes healthy cholesterol metabolism by a variety of actions. It has the ability to upregulate LDL-receptors on liver cells that shuttle cholesterol out of the blood and into the necessary cells. Berberine inhibits intestinal cholesterol absorption and increases excretion as well as provides antioxidant defense. By activating AMPK, for the purposes of glucose balance, it also increases fatty acid oxidation (burning) and decreases fatty acid synthesis. As a highly bioavailable form of berberine, Glucovantage® dihydroberberine may help maintain healthy blood glucose and lipid levels in the normal range while supporting vascular health.\u003c\/p\u003e\n\u003cp\u003eAdvantra-Z\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e(Citrus Aurantium)\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eSynephrine is a naturally-occurring alkaloid with adrenergic agonist activity, structurally related to epinephrine, norepinephrine, ephedrine, and other compounds with a phenethylamine base structure. Despite its chemical similarity to these compounds, synephrine in its various isomers exerts unique effects on adrenergic receptors, in particular, and the human body, in general.\u003c\/p\u003e\n\u003cp\u003eSynephrine exists in three isomer forms: para-, meta- and ortho-synephrine. The molecular changes between the three isoforms are minute, but even this small change results in significant alterations to each isomer’s physiological and pharmacokinetic profile. Two of synephrine’s isomers, both p- and m-synephrine, have been shown to naturally occur in mammals (in low concentrations). As a sympathomimetic, synephrine has been the subject of numerous trials, assessing its effects on weight management, thermogenesis, metabolic rate, and caloric expenditure. In a double-blind, randomized, and placebo-controlled trial involving 10 healthy individuals, the p-synephrine isomer was administered at a 50mg serving, both alone, and in combination with hesperidin and naringin. The authors measured resting metabolic rate (RMR), blood pressure, and heart rate, along with subjective feelings of mood and energy, at baseline, and at 45-mintues and 75-minutes after ingestion. The authors reported a significant increase in RMR in each of the supplement groups, relative to placebo.\u003c\/p\u003e\n\u003cp\u003eIn addition to studies on synephrine in its various isomers, Advantra-Z®, the specific form of synephrine utilized in Core BURN, has itself and in combination with other ingredients, been the subject of various clinical trials in humans. In a randomized, double-blind, placebo-controlled trial featuring 70 obese adults, a formulation containing Advantra-Z® was found to significantly reduce fat mass, body weight, and hip and waist girth as compared to controls, while leading to an increase in lean mass. As the authors comment, these results are in-line with a recent systematic review of human clinical studies involving Citrus aurantium, that revealed the ingredient to reliably increase resting metabolic rate up to 7.2%, increase energy expenditure of up to 13.4%, and weight loss of over 2.9 kg, with no serious adverse events in any of the trials.\u003c\/p\u003e\n\u003cp\u003eIn addition, the combination of caffeine and synephrine appears to potentiate each ingredient’s effects – with rates of fatty acid liberation, heart rate, metabolic rate, and fatty acid oxidation increased in clinical trials featuring the combination. In the same systematic review mentioned above, the authors note that the combination of synephrine and caffeine led to a small but significant reduction in fat mass of 3lbs, and a reduction in bodyfat of 2.9%.\u003c\/p\u003e\n\u003cp\u003eCombined with not only caffeine, but the other ingredients in Core BLAZE, Advantra-Z® appears to be a potent weapon in the arsenal for body composition and weight management.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCapsimax\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMany people have eaten red chili peppers. But did you know that these peppers have an effective benefit when it comes to boosting metabolism and aiding in weight management? These compounds, known as capsaicinoids, are responsible for the “burnin” or hot sensation experienced when consuming spicy food. Capsimax is a concentrated extract of these capsaicinoids from these peppers in a safe and easy on the stomach form, so you can reap the benefits without the negative stomach discomfort commonly associated with capsaicin.\u003c\/p\u003e\n\u003cp\u003eThe capsaicinoids found in Capsimax are absorbed through the gastrointestinal tract and then dispersed throughout the body. Their ability to influence weight management and energy metabolism are governed by specific activation processes. Activation of sarcoplasmic reticulum Ca+ ATP-ase (SERCA) and Uncoupling Protein (UCP1) convert working energy in ATP into heat energy. This process is known as thermogenesis. Transient receptor potential cation channel subtype 1 (TRVP1) are found in the sensory tissue as well as GI, liver, and adipose tissues. The activation of TRVP1 has the potential to reduce visceral adipose tissue by increasing lipolysis, fat oxidation, and reducing appetite.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eYohimbine HCL\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eExtracts or preparation of Pausinystalia yohimbe, and related sub-species, have been used in traditional and folk medicinal systems such as Ayurveda and Unani for centuries. More recently, the principal bioactive compound in Pausinystalia yohimbe, both as a whole plant, and its extracted components, has been the subject of numerous clinical trials investigating its various physiological pathways.\u003c\/p\u003e\n\u003cp\u003eIn particular, recent research has shown that yohimbine exerts a powerful pre-synaptic inhibiting effect on alpha-adrenergic receptors – making it a potent adrenergic antagonist. This effect seems to be localized and largely specific to adipocytes, attaching to their adrenergic receptor sites and preventing them from receiving the catecholamines (norepinephrine and epinephrine) that would normally initiate growth signals.\u003c\/p\u003e\n\u003cp\u003eWhile limited, there is some evidence in human, clinical trials to suggest that Yohimbine’s postulated mechanisms of action translate into practical effects. In a placebo-controlled trial involving 20 healthy, lean soccer players, subjects were given 20mg\/day in two equal servings, for 21 days. At 21 days, the Yohimbine group reflected small but significant reductions in both total fat mass and bodyfat percentage as compared to controls – at least partially suggesting that Yohimbine may have a plausible role in combination with diet and exercise in weight management.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"140 Capsules","offer_id":40061392355508,"sku":"coreblaze","price":44.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/core-blaze_1800x1800_3f5d2ba9-1edf-471d-a21d-0fee75c62fda.jpg?v=1624811466"},{"product_id":"core-post-protein-recovery-matrix","title":"Core Post-Protein\/Recovery Matrix","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Post\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eIt has been called the most important meal of the day, “the anabolic window”, and eating for anabolism. Whatever name you give it, the premise remains: post-workout nutrition is crucial to reaching your fitness and physique goals. Post-workout nutrition plays a number of critical anabolic (tissue building) functions, chief among them being the maximization of glycogen storage and protein synthesis, while simultaneously minimizing protein breakdown and the excessive release of catabolic (tissue destroying) hormones. Incomplete or insufficient post-workout nutrition isn’t a recipe that will likely yield a tasteful result.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThis all raises the question: what is the ideal post workout nutrition? Is it common knowledge, or an industry secret? Maybe a certain ratio of carbohydrates to protein, or fat to protein; maybe the timing, frequency, and method of ingestion? Well, we are here to offer some clarifying insight. To be honest, the situation is vastly less complex, more well-known, and easier to implement than most would have you believe.\u003c\/p\u003e\n\u003cp\u003eHigh quality, fast-digesting carbohydrates and protein have been shown time and again to induce the most optimal conditions for growth in clinical studies – and that is precisely what Core has attempted to emulate with Core POST. Core POST takes the guesswork out of post workout recovery, containing the fast-acting proteins and carbs (whey isolate, dextrose, and Cluster Dextrin®), along with other anabolic agents (free-form L-Leucine, Velositol®, VitaCherry®, and Bioperine®) needed to increase absorption in order to maximize muscle recovery after weight training. This combination of ingredients can quickly replenish muscle glycogen and shuttle much needed amino acids to muscle cells. Whether you are bulking up or slimming down, all of these ingredients are crucial for proper recovery.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecovery Carb Blend (Dextrose and Cluster Dextrin®):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs mentioned above, one of the main goals post workout is to restore muscle glycogen that has been depleted during the workout. The body will even break down muscle tissue for this purpose if an adequate influx of glucose – obtained from the consumption of carbohydrates – is not provided. For this reason, it is vital to include carbohydrates in the post-workout drink.\u003c\/p\u003e\n\u003cp\u003eThough\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eopinion\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003evaries, the scientific literature is relatively clear that fast–digesting carbohydrates such as dextrose and Cluster Dextrin® create optimal conditions for the post-workout synthesis of both skeletal muscle protein and muscle glycogen. Not only have both of Core POST’s carbohydrates sources demonstrated higher rates of post-exercise glycogenesis (glycogen resynthesis) as compared to other carbohydrate sources, they have also been shown to optimize insulin response and blunt cortisol release to a greater degree than other carbohydrate sources.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDextrose\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003efunctions at such a higher capacity because of molecular structure, given that it is otherwise known as pure glucose – your body’s preferred energy substrate and the necessary component for the synthesis and resynthesis of glycogen. Bypassing the lengthy and metabolically costly process of digestion and breakdown, dextrose can be absorbed directly through the gut into the bloodstream and can cause an insulin response faster than any other carb. Additionally, since dextrose is already in the form the body requires, it can be used immediately for glycogen replenishment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCluster Dextrin®\u003c\/strong\u003e, the second carbohydrate source in Core POST, is derived from corn. This carb source is extremely efficient in its digestion and exhibits little to no abdominal bloating. Research conducted on top swimmers, swimming in a flowing water pool, confirmed that Cluster Dextrin’s fast gastric emptying contributed to increased endurance (longer swim times). Swimmers provided a sports drink containing Cluster Dextrin had approximately 50% longer swim time than swimmers provided a mixture of water and glucose only.\u003c\/p\u003e\n\u003cp\u003eIn combination, the carbohydrates in Core POST, in their precise serving sizes, interact to form a comprehensive post-workout nutrition strategy:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eDextrose acts quickly to create an immediate supply of glucose and to stimulate post-workout insulin levels.\u003c\/li\u003e\n\u003cli\u003eDue to their molecular structure, Cluster Dextrin® balance that insulin response.\u003c\/li\u003e\n\u003cli\u003eTogether, they all rapidly, and in a sustained fashion, provide your body with a prime environment for the synthesis of both glycogen and skeletal muscle\u003c\/li\u003e\n\u003cli\u003eAnd most importantly, they do so without the bloat!\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eClinical research is clear that carbohydrates of this type, in combination with whey protein isolate, rapidly reverse high levels of cortisol and low levels of insulin that are associated with high intensity exercise. The rapid, but very beneficial, influx of glucose from oral carbohydrate supplementation quickly suppresses cortisol and the negative effect it has on the expression of metabolically critical proteins and growth factors – ensuring that myocytes (muscle cells) function in an ideal environment. In addition, these carbohydrates induce a beneficial insulin response, the effects of which include stimulating glycogen storage, the transport of glucose into muscle cell mitochondria, and an increase in amino acid utilization.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCold-Processed Microfi¬ltered Non-GMO Whey Protein Isolate:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIf the post-workout environment were a jungle, whey protein isolate would be the lion – its king. While it is difficult to overstate the critical role that post-exercise protein consumption plays in both a macro (body composition) and micro (small-scale, physiological changes) context, some ambiguity remains: what is the ideal form, frequency, timing, and amount of protein consumption post-exercise? Luckily for you, Core Nutritionals’ research hounds have crunched the numbers and read the studies for you, and the result is a very precise amount of whey protein isolate included in Core POST.\u003c\/p\u003e\n\u003cp\u003eIn a statement that should not surprise a single athlete or casual weightlifter, intense resistance training has a profound effect on the function and structure of skeletal muscle and muscle proteins. Immediately following an intense bout of resistance exercise, a process known as muscle protein breakdown – with its sidekick, leucine oxidation – begin to literally tear down your skeletal muscle from the inside. While resistance training simultaneously increases a process known as protein synthesis, the fractional synthesis rate (how quickly the protein is synthesized) is often far exceeded by the rate of muscle protein breakdown and leucine oxidation. The result is that, in that absence of mitigating factors such as post-workout nutrition, your body is in a state of negative protein balance – i.e., catabolism.\u003c\/p\u003e\n\u003cp\u003eIn order to counteract a negative intramuscular protein balance, a number of things need to occur – mostly, a rapid increase in the availability of amino acids, and the optimization of several metabolically critical hormones (such as insulin). The combination of protein and carbohydrates contained in Core POST achieves precisely this balance, and research on whey protein and dextrose in combination demonstrates that this combination maximizes the stimulation of muscle protein synthesis and results in even greater muscle anabolism than either alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFree Form Vegan Leucine:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe branch-chained amino acids leucine, isoleucine, and valine are famous for their role in skeletal muscle protein synthesis and metabolism, and additionally comprise approximately one-third of all skeletal muscle protein. Of the three, leucine is both the most physiologically important with respect to muscle mass, and the most extensively studied. Data on leucine demonstrate this amino acid plays critical roles in stimulating skeletal muscle protein synthesis, and ribosomal biogenesis and assembly (the literal building of muscle tissue), along with playing a lesser role in insulin signaling and gluconeogenic processes. As a result of these diverse roles, leucine has been demonstrated to significantly stimulate skeletal muscle protein synthesis, and attenuate protein degradation, by both insulin-mediated and non-insulin mediated mechanisms.\u003c\/p\u003e\n\u003cp\u003eLeucine’s insulin-mediated effects are largely the result of its activation of the classical insulin receptor substrate (IRS)\/phosphatidylinositol (PI) 3-kinase (PI3K)\/Akt\/mTOR signal transduction pathway. In this pathway, the bonding of a substrate (Insulin activates a compound known as PI3K, which in turn activates, Akt. Once phosphorylated and activated, Akt signals the release of the famous mammalian target of rapamycin (mTOR). mTOR then increases the translation of muscle-cell ribosomal proteins that increase ribosome biogenesis, which is the literal production of proteins. Leucine plays a critical role in all of this, creating the translation initiation factors that are the rate-limiting step in the production of the ribosomes spoken about above. Carbohydrates alone, other essential amino acids, and non-essential amino acids have not been shown to have the stimulatory effects on muscle protein synthesis – leucine alone has, highlighting is primacy as a muscle protein activator. Leucine has additionally been shown to positively regulate protein synthesis independent of insulin. In certain trials where rapamycin and leucine were co-administered, rapamycin showed only partial inhibition of leucine’s effects on muscle protein synthesis. Rapamycin is also a critical component to the PI3K\/Akt\/mTOR pathway, as the mTOR (mammalian target of rapamycin) suggests. One of rapamycin’s primary functions is to inhibit mTOR. So, if leucine-mediate protein synthesis is only partially blocked by rapamycin, but rapamycin fully inhibits mTOR, this suggests that leucine-mediate protein synthesis is only partially dependent on the PI3K pathway.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVelositol®:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVelositol®, a patented complex of amylopectin\/chromium, is a fascinating compound – with emerging clinical data to suggest that it is effective in significantly enhancing skeletal muscle protein synthesis when combined with whey protein (vs whey alone).\u003c\/p\u003e\n\u003cp\u003eIn a double-blind crossover study, featuring 10 exercise-trained adults, researchers combined Velositol® with 6g of whey protein to measure what effects, if any, the compound would exert on skeletal muscle protein synthesis. (The control group consumed 6g of whey alone.) After collecting baseline muscle biopsies – to measure phenylalanine, a marker of muscle-building – the subjects performed eight reps of leg extensions. A final muscle biopsy was taken post-workout, to measure the changes in muscle protein synthesis between the study and control group.\u003c\/p\u003e\n\u003cp\u003eThe results were significant: the researchers found that muscle protein synthesis had nearly doubled in the Velositol® group, compared to the control. The researchers hypothesized that the mechanism of action of Velositol® is the stimulated uptake of leucine and other amino acids due to an influx of insulin (from the chromium).\u003c\/p\u003e\n\u003cp\u003eWhile further study is warranted, the existing data on Velositol® suggests it’s a must-have addition to any recovery matrix.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitacherry®:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitacherry®, comprised of Montmorency tart cherries, is a highly studied ingredient that has been shown to aid in muscle recovery as well as protect against post-exercise soreness and fatigue. Vitacherry® is filled with free radical fighting phytonutrients and compounds that work synergistically synergistically work together to reduce exercise induced inflammation. A 2016 study including 27 participants looked at the benefits of short-term supplementation with Montmorency tart cherries surrounding an endurance event showed positive results when it came to the benefits listed above. ItWhat was found was that supplementation in conjunction with a a vigorous exercise event had positive benefits towards:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eReduced immune and inflammatory response to stress\u003c\/li\u003e\n\u003cli\u003eIncreased performance\u003c\/li\u003e\n\u003cli\u003eReduced soreness perception\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eBioPerine®:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBioPerine® is a patented standardized extract from the fruit of Piper nigrum (black pepper). ItsIt’s studied benefits have shown improvements in bioavailability of nutrients it is surrounded by. When it comes to post exercise nutrition, efficiency and speed with which nutrients can enter the system and get to their target is of the upmost importance. The “window of opportunity” is much larger than what has been previously thought, but when your results weigh heavily on post-exercise nutrition, maximal absorption and use of nutrients is extremely important.\u003c\/p\u003e\n\u003cp\u003eBioPerine® primarily works through mechanisms and channels that can inhibit intestinal motility and dilate blood vessels of the intestines (where absorption of nutrients occurs). This physiological action may cause increased absorption and digestion of nutrients.\u003c\/p\u003e\n\u003cp\u003eSeveral studies looking at BioPerine®’s impact on nutrient absorption have been done. One study looking at the efficacy of BioPerine® on serum concentrations of curcumin showed bioavailability was improved by more than 500%. Therapeutic effectiveness of curcumin has often been exhibited as low. Another study conducted over the course of 6 weeks on BioPerine® influence on serum selenium levels in humans showed an increase by 145% over the presupplementation value.\u003c\/p\u003e\n\u003cp\u003eWith promising research being done on the effects of BioPerine® in the context of nutrient absorption and bioavailability, it is only fitting that we include it in Core POST, when post workout nutrition is King!\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"20 Servings \/ Fruity Cereal","offer_id":40061473063092,"sku":"corepostworkout-1","price":59.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Hot Cocoa","offer_id":40061473095860,"sku":"corepostworkout-2","price":59.95,"currency_code":"USD","in_stock":true},{"title":"20 Servings \/ Peanut Butter Brittle","offer_id":40061473128628,"sku":"corepostworkout-3","price":59.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Cinnamon French Toast","offer_id":44380505964786,"sku":"corepostworkout-4","price":59.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Hot Cocoa (Best by 3\/26)","offer_id":49988463886578,"sku":"corepostworkouthotcomd","price":30.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/POST-Fruity-Cereal_1800x1800_019b0ed4-f618-4705-8dba-75d0ae18a588.jpg?v=1624813747"},{"product_id":"core-load-gda","title":"Core GDA","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutritionals GDA\u003c\/h2\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eCore Life Line GDA is a glucose disposal agent (GDA) formulated with a blend of ingredients commonly used in carbohydrate management and nutrient-partitioning supplements. The formula combines multiple ingredients rather than relying on a single active compound.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eDesigned for use alongside meals containing carbohydrates, Core Life Line GDA contains ingredients selected for their role in glucose metabolism and nutrient utilization pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eThe formula can be incorporated into nutrition plans by individuals looking for a glucose disposal supplement as part of their daily routine.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"isSelectedEnd\"\u003eCore Life Line GDA Highlights\u003c\/h3\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\u003cspan\u003eGlucose disposal agent (GDA) formula\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMulti-ingredient blend\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDesigned for use with carbohydrate-containing meals\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eFeatures ingredients commonly used in nutrient-partitioning supplements\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eNon-stimulant formula\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eConvenient capsule format\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 class=\"isSelectedEnd\"\u003eCore GDA Supplement Facts\u003c\/h3\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/GDA_SFP_480x480.jpg?v=1781409086\" alt=\"\" style=\"float: none; display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/div\u003e\n\u003cdiv data-is-intersecting=\"true\" data-turn-id-container=\"request-6a248c67-fb38-8329-aa72-3b17e2f533ca-23\" class=\"\"\u003e\n\u003csection data-turn=\"assistant\" data-scroll-anchor=\"false\" data-testid=\"conversation-turn-36\" data-turn-id-container=\"request-6a248c67-fb38-8329-aa72-3b17e2f533ca-23\" data-turn-id=\"request-6a248c67-fb38-8329-aa72-3b17e2f533ca-23\" dir=\"auto\" class=\"text-token-text-primary w-full focus:outline-none has-data-writing-block:pointer-events-none [\u0026amp;:has([data-writing-block])\u0026gt;*]:pointer-events-auto R6Vx5W_threadScrollVars scroll-mb-[calc(var(--scroll-root-safe-area-inset-bottom,0px)+var(--thread-response-height))] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\"\u003e\n\u003cdiv class=\"text-base my-auto mx-auto pb-3 [--thread-content-margin:var(--thread-content-margin-xs,calc(var(--spacing)*4))] @w-sm\/main:[--thread-content-margin:var(--thread-content-margin-sm,calc(var(--spacing)*6))] @w-lg\/main:[--thread-content-margin:var(--thread-content-margin-lg,calc(var(--spacing)*16))] px-(--thread-content-margin)\"\u003e\n\u003cdiv class=\"[--thread-content-max-width:40rem] @w-lg\/main:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\" data-conversation-screenshot-content=\"\"\u003e\n\u003cdiv class=\"flex max-w-full flex-col gap-4 grow\"\u003e\n\u003cdiv data-turn-start-message=\"true\" class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal outline-none keyboard-focused:focus-ring [.text-message+\u0026amp;]:mt-1\" data-message-model-slug=\"gpt-5-5\" dir=\"auto\" data-message-id=\"ab7f14c1-334d-45d2-b928-cae9dc034f63\" data-message-author-role=\"assistant\" tabindex=\"0\"\u003e\n\u003cdiv class=\"flex w-full flex-col gap-1 empty:hidden\"\u003e\n\u003cdiv class=\"markdown prose dark:prose-invert wrap-break-word w-full dark markdown-new-styling\"\u003e\n\u003cp\u003e\u003cem\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eServing Size: 6 Capsules | Servings Per Container: 30\u003c\/strong\u003e\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul data-end=\"117\" data-start=\"0\"\u003e\n\u003cli data-end=\"117\" data-start=\"62\" data-section-id=\"1n62gwg\"\u003eChromium (as Chromium Picolinate) (Chromax®) – 200mcg\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-end=\"141\" data-start=\"119\"\u003e\u003cstrong data-end=\"141\" data-start=\"119\"\u003eActive Ingredients\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul data-end=\"500\" data-start=\"143\"\u003e\n\u003cli data-end=\"232\" data-start=\"143\" data-section-id=\"g3m6k1\"\u003eGreen Coffee Bean Extract (Coffea robusta) (Seed) (std. 50% Chlorogenic Acids) – 2000mg\u003c\/li\u003e\n\u003cli data-end=\"314\" data-start=\"233\" data-section-id=\"1acs33w\"\u003eGS4 Plus® Gymnema sylvestre Extract (Leaves) (std. 25% Gymnemic Acids) – 1000mg\u003c\/li\u003e\n\u003cli data-end=\"371\" data-start=\"315\" data-section-id=\"ncgqno\"\u003eCeylon Cinnamon Bark Powder (Cinnamomum verum) – 500mg\u003c\/li\u003e\n\u003cli data-end=\"412\" data-start=\"372\" data-section-id=\"1eo2x12\"\u003eGlucoVantage® Dihydroberberine – 200mg\u003c\/li\u003e\n\u003cli data-end=\"500\" data-start=\"413\" data-section-id=\"1dmhb4s\"\u003eBanaba Leaf Extract (Lagerstroemia speciosa) (Leaf) (std. 20% Corosolic Acid) – 125mg\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003c\/div\u003e","brand":"Core Nutritionals","offers":[{"title":"180 Veggie Caps","offer_id":40584117452980,"sku":"coreloadgda","price":44.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/GDA_FRONTLarge.jpg?v=1781409086"},{"product_id":"core-gut-support","title":"Core Gut Support","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutrition Gut Support\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eThe gut, or gastrointestinal (GI) tract is one of the largest systems responsible for keeping our body in working order. Food and a wide variety of nutrients pass through the separate parts, being broken down and absorbed only to be shuttled to their final destination to begin to do their job. In addition to this food, countless numbers of microorganisms from the environment pass through the gut – some of which may be detrimental to health and alter the integrity of the GI tract. Core GUT was formulated to provide all around GI tract support with beneficial bacteria in a custom probiotic blend, a useable form of food for these microorganisms in a prebiotic, beneficial by-products in a post biotic, and digestive enzymes to aid in the breakdown of crucial nutrients. This combination of ingredients has been shown to support the growth of healthy gut bacteria*, enhance immune function*, provide support for gut lining integrity*, and display protective effects on gut environment*.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eCore Nutritionals Gut Support Highlights\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eCore Probiotic Blend™\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCustom formulated blend of live organisms to provide the gut with beneficial bacterial support.\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eCore Biome® Tributryin\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\nPostbiotic that aids in the body's inflammatory response and stimulating growth of new cells\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eSunFiber® \u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePrebiotic fiber that can help increase the absorption of important macronutrients and vital minerals\u003c\/p\u003e\n\u003ch3\u003eGut Support Supp Facts\u003c\/h3\u003e\n\u003ch4\u003eBifidobacterium 8.5 billion CFU\u003c\/h4\u003e\n\u003cp\u003eBifidobacterium are labeled as probiotics and normally live in the intestines and stomach. They are essential for helping your body perform essential functions such as digestion and fighting off harmful bacteria.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBifidobacterium breve (2 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOne of the most helpful probiotic bacteria in the human body. Widely used probiotic strain for pediatrics. Healthy amounts of this strain can improve gut related issues such as diarrhea, gas, allergies, and irritable bowel syndrome (IBS)\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBifidobacterium infantis (2 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis specific probiotic strain that is often used to alleviate irritable bowel syndrome as well as general abdominal discomfort and bloating.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBifidobacterium bifidum (2 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBifidobacterium bifidum has shown promise in improving irritable bowel syndrome (IBS) constipation, lung infections, ulcerative colitis, diarrhea, and certain intestinal infections.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBifidobacterium longum (2 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBifidobacterium longum is classified as a multifunctional probiotic strain that has been shown to be highly effective in alleviating GI distress, immunological and infectious diseases. These benefits have been shown to be attributed to its ability to stabilize the gut microbiota and improve the overall intestinal environment.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBifidobacterium lactis (500 million CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eLactic acid bacteria are among the most populated microflora that live within the human large intestine. They are believed to be play an integral role in the homeostasis of the gut microbiome as well as are highly beneficial for overall health. \u003c\/p\u003e\n\u003cp\u003eLactobacillus 16.5 billion CFU\u003c\/p\u003e\n\u003cp\u003eAs arguably the most common probiotic group, Lactobacillus can aid the body in the breakdown of foods, absorption of key nutrients, and defend against destructive organisms that can cause distress and other diseases.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus acidophilus (4 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOne of the most common probiotic types that can be most commonly found in many fermented foods, and added to yogurts, and cheeses. This type of bacteria is found in the intestines and plays a vital role in boosting human health. This bacterium helps produce lactic acid. It goes through a process of producing an enzyme called lactase, which helps break down lactose into lactic acid. This bacterium has been extensively studied for its benefits of alleviating symptoms pertaining to IBS, diarrhea, bloating, and other GI distress.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus plantarum (2 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eL. plantarum has a significant importance on boosting antioxidant activity as well as helping maintain intestinal permeability. It can work to suppress the growth of bacteria that produce gases in the intestines as well as benefit some who suffer from IBS.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus bulgaricus (2 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eL. bulgaricus has been used mostly as a probiotic to help aid in the improvements of digestion, prevent diarrhea, and to relieve symptoms associated with IBS. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus casei (2 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNaturally found in the gut as well as some fermented foods, L. casei has been shown to positively regulate our digestive system by contributing to the reduction of diarrhea. It can also positively impact constipation, Crohn’s disease, inflammatory bowel disease (IBD), IBS, lactose intolerance, and ulcerative colitis.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus rhamnosus (2 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eL. rhamnosus is able to promote immune-responsiveness by reducing the expression of several activation and inflammation markers on monocytes and by increasing the production of interleukin in macrophages. It produces a biofilm that can protect the mucosa and also produces soluble fibers that are beneficial to the gut.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus brevis (2 billion CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eL. brevis is a type of lactic acid bacteria found in milk-based products, fermented products, and in some plants as they decompose. Its benefits include alleviating diarrhea related symptoms in children and supporting natural killer (NK) cell activity in older individuals. These NK cells are a type of pathogen-killing cell that can fight off infections and stop the growth of cancerous cells.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus gasseri (500 million CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eL. gasseri is a unique strain of bacteria commonly found in the genital, urinary, and digestive systems of the body. It possesses many benefits but it has shown particular promise in aiding positive changes in weight and improvements in body composition. It has also shown promise in reducing blood and liver cholesterol, and reducing oxidative stress in the body. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus fermentum (500 million CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eL. fermentum has been reported to enhance immunologic response as well as prevent community-acquired GI and upper respiratory infections. This specific strain of Lactobacillus also produces potent antimicrobial peptides, which can then be used as a food preservative or as alternatives in antibiotics. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus reuteri (500 million CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis well studied strain of Lactobacillus can colonize a large number of mammals and provide essential benefits. Found in the GI tract, urinary tract, skin, and breast milk, the benefits of this strain include the production of antimicrobial molecules that can inhibit the colonization of pathogenic microbes and strengthen the microbiota composition of its host. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus paracasei (500 million CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAs a potent strain with immune modulation properties, several studies have shown that L. paracasei can provide relief from inflammatory bowel disease as well as alleviate inflammatory symptoms associated with colitis and other colon related issues.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus salivarius (500 million CFU)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis probiotic species is widely found in the GI tract of mammals and has been shown to possess benefits that include relief from IBS related symptoms, pancreatic necrosis, and atopic dermatitis.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSaccharomyces 5 billion CFU\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSaccharomyces boulardii (5 billion CFU) is a specific type of probiotic yeast that has been shown to possess benefits for human gastrointestinal health. The probiotic benefits of this organism include fighting against toxins and other harmful bacteria, increasing the function of the gut biome, providing inflammation relief for the gut lining to improve efficiency, boosting immune function, and helping to restore optimal nutrient levels, like short chain fatty acid production, for the gut.\u003c\/p\u003e\n\u003cp\u003eTributyrin (as Core Biome™ 30% yielding 300mg)\u003c\/p\u003e\n\u003cp\u003eThe gut microbiome is responsible for contributions that maintain intestinal balance. Disturbances in this homeostasis can cause alterations in the metabolic and fermentation byproducts that occur in the gut. With the gut being so closely tied to many bodily processes involving many of the body’s vital systems, optimal gut health is of importance. The microbiota of the gut ferment undigested sugars to product short-chain fatty acids such as, acetate, propionate, and butyrate. Butyrate is especially essential as it has mechanisms of action that include effects of suppressing inflammation and immunoprotection, serving as the primary nutrient that provides energy to colonocytes, and regulating functions of gene expression, gut tissue development, oxidative stress reduction, and diarrhea control. When butyrate is depleted or scarce, GI distress and other injury can occur.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eSunfiber® Guar Fiber\u003c\/p\u003e\n\u003cp\u003eSunfiber®, a fermented, dietary fiber, is a proven prebiotic fiber that increases both Bifidobacteria and Lactobacillus levels with the aim of providing digestive support. These beneficial bacteria promote a healthy gut microbiota and aim to enhance the overall function of the gut, thus leading to increased function of the other vital systems of the human body. \u003c\/p\u003e\n\u003cp\u003eDigestive Enzyme Blend (Protease, Lactase, Amylase, Lipase)\u003c\/p\u003e\n\u003cp\u003eOne can easily make the argument that dietary enzymes – and in particular, digestive enzymes – are the most consistently underrated and overlooked component to a supplementation regimen. These powerful little protein structures influence or outright control a vast, complex network of bodily functions. In a fitness-specific context, digestive enzymes play an absolutely crucial role in the breaking down of dietary carbohydrates, fats, and proteins into their constitutive parts, and therefore allow your body to use them in various processes (glycogenesis, protein synthesis, etc).\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":42079977046258,"sku":"coregut","price":54.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/gut_1800x1800_e0dd0721-2af4-4750-9dde-ca3be60b728b.jpg?v=1637382638"},{"product_id":"core-soothe","title":"Core Soothe","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutritionals Soothe Inflammation Support\u003c\/h2\u003e\n\u003cp\u003eCore SOOTHE offers an additional layer of relief and protection. Formulated with clinically researched ingredients that have proven time and time again to support tissue repair, like those seen from Cissus quadragularis, antioxidant support, from Phyto-C™; and inflammatory suppression, from Boswellia, Curcumin and Ginger Extract. The synergistic nature of these ingredients is unmatched by any product that we have ever seen, as far as suppressing harmful free radical advancement, and aiding in strengthening vital supporting structures is concerned. That's what led us to developing this blend, and that's why you need Core SOOTHE.\u003c\/p\u003e\n\u003ch3\u003eCore Soothe Highlights\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eCissus quadrangularis\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- improved joint integrity and function.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBoswellia\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- promotes healthy tendon and cartilage strength..\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCurcumin\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- suppresses pro-inflammatory compounds\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Nutrition Soothe Supp Facts\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCissus Quadrangularis Extract (stem) (5% ketosterones)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCissus quadrangularis (CQ) is a plant with a long history of use in traditional and folk medicinal systems, including thousands of years of documented use in the Siddha and Ayurvedic traditions. While the specific use of Cissus in these systems varied, the most common traditional preparations related to analgesia, general tonics, and bone fracture healing. More recent research has developed physiological explanations for CQ’s traditional efficacy, including the reduction of pro-inflammatory cytokines, modulation of the glucocorticoid system (in animal trials), and the proliferation of osteoblast (bone-forming cell) DNA.\u003c\/p\u003e\n\u003cp\u003eSpecific to bone formation, there is strong data to suggest that CQ increases the accumulation of compounds known as mucopolysaccharides – long chain sugar molecules that precede mineralization in the process of bone formation. Think of these compounds sort of like the wet newspaper before it becomes paper mache. As stated, separate research also suggests that extracts of CQ stimulated osteoblastogenesis, the process of forming bone cells.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBoswellia Extract (Boswellia serrate) (Gum resin) (65% boswellic acids)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBoswellia is a tree resin extract that is a traditional part of Indian medicine. In modern clinical trials the active agent, boswellic acid, and the gum resin it contains possesses monoterpenes, diterpenes, triterpenes, tetracyclic triterpenic acids, and four pentacyclic triterpenic acids, which are responsible for the inhibition of pro-inflammatory enzymes. Out of the four pentracyclic triterpenic acids, acetyl-11-keto-β-boswellic acid is the most potent inhibitor of 5-lipoxygenase, an enzyme responsible for inflammation. In human study’s, Boswellia has shown effectiveness in the managements of osteoarthritis and other joint related conditions. Several studies proved that Boswellia extract was effective at reducing pain and stiffness, increasing pain threshold, as well as improving overall joint function when compared to placebo. Similarly, to curcumin, boswellic acids have demonstrated a significant attenuation of NF-kB production in various animal and in vitro assays. Curcumin and Boswellia in combination as a treatment method for osteoarthritis has also showed beneficial results. One clinical human trial showed that this combination was able to increase the efficacy of osteoarthritis treatments due to its synergistic effects on oxidative stress reduction.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCurcumin (Curcuma longa) (95% Curcuminoids)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCurcumin, the primary polyphenol found in turmeric (a root known for its spice), has been the basis of many clinical studies for its therapeutic properties and ability to modulate multiple cells signaling pathways in certain inflammatory diseases known to humans.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eGingever® (Zingiber officinale) (root) (Ginger Extract 10%)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eGinger is a flowering plant from the Zingiberaceae family with a lengthy history of culinary and medicinal use largely attributed to the therapeutic value of its antioxidant and anti-inflammatory properties.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003ePhyto-C™ (Acerola extract, blueberry, strawberry, maqui berry, acai, tart cherry, kale, broccoli, green tea extract, green coffee bean extract, turmeric extract)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePhyto-C™ is a trademarked complex blend of antioxidant rich superfoods clinically formulated to deliver a host of immune system supporting benefits. Combining ingredients such as blueberries, acai, tart cherry, kale, broccoli, green tea, turmeric, and others, you are ensuring that your body is being provided clinically proven and laboratory tested superfoods that will protect against free radicals and other cell destroying compounds. This neutralization of free radicals can protect vital cells, prevent illnesses, and reduce overall inflammation. Inflammation can disrupt normal cell processes thus leading to cell damage and disease. Inflammatory cells produce mediators such as cytokines, arachidonic acid, and other factors, which can precipitate a cascading negative reaction within the body. If this inflammation is not addressed in a reasonable manner, potentially permanent cell damage can occur. The key is to reach a point of equilibrium between free radical formation and antioxidant defense mechanisms. As a potent antioxidant source, Phyto-C™ can provide beneficial antioxidants for the body that can aid in this equilibrium and work to boost the immune system and overall health of the human body\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBioperine® (Black Pepper Extract) (Piper nigrum) (fruit) (std. to 95% Piperine)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBioPerine® is a patented standardized extract from the fruit of Piper nigrum (black pepper). It’s studied benefits have shown improvements in bioavailability of neighboring nutrients. When suppressing inflammation, overall efficiency and rapid delivery to the targeted cells have a multiplicative impact that enhances the overall therapeutic value of the administered compounds and nutrients. BioPerine® helps to increases the bioavailability and absorption of the aforementioned ingredients within Core Soothe.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":42080052707570,"sku":"coresoothe","price":54.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/Soothe1_1800x1800_c5820ac6-90ff-4a5b-bc16-22c7ec4abdd9.jpg?v=1637382379"},{"product_id":"core-alpha-test-optimizer","title":"Core Alpha Test Optimizer","description":"\u003cp\u003eCore Nutritionals Alpha Test Booster\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCore ALPHA is an all-natural, innovative product featuring ingredients backed by numerous clinical studies. Core ALPHA’s ingredients are not only all-natural but powerful – providing a range of ingredients to support healthy hormone function and balance. As with all Core Nutritionals’ products, Core ALPHA’s ingredients are included in a non-proprietary blend featuring clinical servings, so you know exactly what you are supplementing.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eCore Nutrition Alpha Test Highlights\u003c\/span\u003e\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eN-methyl-D-aspartic acid (NMDA)\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- Supports healthy testosterone levels\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e3-desoxy, 7-keto-DHEA\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- Supports healthy estrogen levels\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eColeus forskohli root extract\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- Assists in healthy weight management\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e2 capsules per serving.\u003c\/li\u003e\n\u003cli\u003e28 servings per container.\u003c\/li\u003e\n\u003cli\u003eHormone balance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Nutritionals Alpha Test Optimizer Supp Facts\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eN-methyl-D-aspartic acid (NMDA)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eD-aspartic acid (DAA) is an amino acid that is found naturally in several endocrine glands, including the testes and pituitary. While the correlation between DAA and testosterone production has been clinically documented, research indicates several possible mechanisms for these effects. It’s likely that DAA acts as a neuromodulator influencing several pathways that govern the reproductive system, particularly testosterone production. Some studies indicate that DAA’s concentrated presence in the hypothalamus, pituitary, and testes identify this protein as an up-regulator of gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), growth hormone (GH), and testosterone. Some studies have found that DAA also stimulates a protein called StAR. StAR is necessary for the cholesterol transport in the cell that is needed for testosterone production. Further, its role in modulating the sexual drive implicates DAA assists nootropic activity, supporting healthy levels of dopamine and serotonin. Balanced levels of dopamine and serotonin have a range of significant benefits.\u003c\/p\u003e\n\u003cp\u003eTo improve on D-aspartic acid we have instead incorporated N-methyl-D-aspartate (NDMA) into the Core ALPHA formula. DAA is converted into NMDA, which is a potent stimulator of the N-methyl-D-aspartate receptor pathway. By directly stimulating this pathway, NMDA is needed only in small doses unlike DAA’s higher dose requirements. In fact, NMDA elicits its hormone releasing action at concentrations approximately 100-fold lower than DAA. Thus, at a 30 mg dose, NMDA, shows promise to support an optimal balance of hormones.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBrassaiopsis glomerulata leaf extract (10:1)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBrassaiopsis glomerulata is a large shrub of the Araliaceae family that occurs in south and Southeast Asia. Throughout Asia, this plant is used to treat rheumatism and back pain, aid in digestion, and treat bone fractures in traditional medicinal systems (TMS). Despite its many medicinal uses, the most interesting aspect of the leaves of Brassaiopsis glomerulata is their ability to reduce the activity of aromatase. Studies show that multiple components of a Brassaiopsis glomerulata leaf extract are capable of aromatase inhibition. The addition of this 10:1 extract in Core ALPHA, along with the 3D7K, gives this product a one-two punch at supporting a healthy estrogen balance.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eMucuna pruriens seed extract (50% L-dopa)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMucuna pruriens is one of the popular medicinal plants of India and is known to contain various beneficial nutritional compounds. The main nutrient found in Mucuna pruriens is L-dopa, which acts as a natural source of dopamine. Prolactin is a hormone released by the pituitary gland, which is believed to exert anti-androgenic effects in men.. Mucuna pruriens’ ability to support healthy dopamine levels may significantly reduce the release of prolactin hormone by the pituitary glands offering powerful benefits. In addition, clinical evidence suggests that Mucuna pruriens not only supports healthy growth hormone levels but also contains naturally occurring serotonin precursors to support mood, memory, and overall well-being. Clinically shown to support optimal balance of growth hormone, prolactin, serotonin and other beneficial hormones, Mucuna pruriens may also assist healthy weight management and stress support.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin D3 (cholecalciferol)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVitamin D3 is an essential hormone precursor that plays a vital role in many metabolic functions, including bone health, , support for immune and blood pressure health, lean body mass, and weight management). Clinical trials have even linked Vitamin D3 with an increase in overall health and well-being. Although some foods contain vitamin D, the human body generates most of its vitamin D needs from the skin through regular exposure to sunlight. Severe vitamin D deficiency is a significant and widespread problem, especially in North America. In addition to its well-known properties for supporting bone density and strength and general inflammatory response, Cholecalciferol is included in Core ALPHA because studies have shown that higher levels of vitamin D in men are correlated with higher levels of circulating testosterone.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eZinc (as zinc aspartate)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eZinc deficiency is prevalent throughout the entire world, including the United States. Both severe and moderate zinc deficiencies are positively correlated with lower testosterone levels in men. And while zinc deficiency has been shown to lower your testosterone levels, zinc supplementation has been correlated with an increase in testosterone levels. Clinical research indicates that zinc deficiency reduces circulating luteinizing hormone and testosterone concentrations, may lower healthy levels of aromatase (increasing estrogen levels), and modifies sex steroid hormone receptor levels, thereby contributing to unhealthy hormone balance and male sexual function. Zinc supplementation with the aspartate form can support optimal zinc absorption and hormone balance.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":42080088785138,"sku":"coretestalpha","price":54.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/Alpha_1800x1800_68e29fbb-e77e-43f4-9f17-f9bc38bcdbaf.jpg?v=1637382604"},{"product_id":"core-liver-support","title":"Core Liver Support","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutritionals Liver Support\u003c\/h2\u003e\n\u003cp\u003eFor many athletes, the liver isn’t the first thing that comes to mind when they think about optimizing their gains and recovery. Yet the liver has an undeniable impact on your overall health and fitness. Its actions aid in the filtering of harmful substances from the blood, production of proteins that carry hormones, drugs and fatty acids throughout the body, creates bile to breakdown fats, and stores glycogen, vitamins and other minerals for use in everyday processes. Conversely, the consistently elevated levels of muscle damage, excessive protein intake and stimulant use typical for your average weightlifter places additional stresses on the liver, leading to increased oxidative stress, liver damage and elevated markers of liver function.\u003c\/p\u003e\n\u003cp\u003eThis dynamic opposition, where liver function is essential for overall fitness and growth while the very processes involved in body recomposition can cause damage and reduce function, requires an effective remedy to aid with short term fitness goals, as well as long term liver health and function. Enter Core LIVER - our comprehensive liver support and detoxification supplement.\u003c\/p\u003e\n\u003ch3\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cspan\u003eCore Nutrition Liver Support Highlights\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMilk Thistle Extract\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- hepatic stress suppression\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKatuki Extract\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- enhances bile production\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTUDCA\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- enhance liver protection\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003e\u003cmeta charset=\"utf-8\"\u003eCore Liver Support Supp Facts\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eMilk Thistle Extract (Silybum marianum) (seed) (80% silymarin)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSilybum marianum, also known as milk thistle, is a medicinal thistle from the aster or daisy family that has been used in traditional medicines for many centuries for treatment of many different diseases. Many of these treatments have been to protect the liver and associated organs from damage\/further damage. There is evidence to support that milk thistle, and specifically the silymarin compound that is found within it, exhibits a mechanism of action for hepatoprotection from free radicals through antioxidant activity, enhanced protein synthesis, and possible anti-inflammatory or immunomodulating effects. These free radicals are generated through the damage to cellular membranes called lipoperoxidation. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKatuki Extract (Picrorhiza kurroa) (rhizome and root)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eKatuki, known by its botanical name Picorrhiza kurroa, comes from the Scrophulariaceae family. Picorrhiza, coming from the Greek word ‘Picroz’, means ‘bitter’ and ‘rhiza’ meaning ‘root’. This bitter quality is what katuki has been touted for its therapeutic benefits and is said to be cooling, cleansing, and possess anti-bacterial properties. Katuki has been shown to possess potent hepatoprotective and hepatostimulative properties to offer support to the overall function of the vital liver organ. Katuki offers support by stimulating the secretion of bile, which assists the liver enzymes in coming back to homeostasis. Additionally, katuki contains a compound called picroliv, or kutkin. This compound is mainly a glucoside (derived from glucose and most commonly found in plants) and is normally isolated from the roots and rhizomes of Picorrhiza kurroa for the uses to treat certain liver ailments. In rodents, picroliv has shown efficacy that can be similar to silymarin in models that have shown hepatic damage. As mentioned above, silymarin is a highly effective compound used in the controlling of hepatic inflammation which can lead to hepatic trauma. When chronic oxidative stress, toxins, and free radicals that can wreak havoc on the liver can be controlled, the function of the liver can be enhanced, thus creating a cascading sequence of related optimally functioning actions. Some of these actions include:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003ethe filtering process of the bodies blood from any poisonous substances like alcohol and other drugs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003ethe production of a blood protein called albumin that is helpful in carrying hormones, drugs, and fatty acids throughout the body as well as aiding in the bodies blood clotting abilities following injury.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003ethe production of bile, which is essential for the breakdown and digestion of fats and transport of other waste.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eThe storage of glycogen, vitamins, and other minerals that can be used for normal everyday processes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSetria® Glutathione\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGlutathione is an amino acid containing molecule of L-glutamic acid, L-cysteine, and Glycine that is particularly concentrated in the liver. The liver has a unique ability to synthesize cysteine, a glutathione precursor, from endogenous sources through the trans-sulphuration pathway or through protein breakdown and food. It is vital to many different properties and is best known for being a powerful antioxidant. It also plays a key role in the detoxification reactions in the liver and in regulation of the thiol-disulfide status of hepatocytes. The ‘glutathione system’ comprises the enzymes that synthesize glutathione within a cell as dedicated enzymes that use glutathione for its antioxidant effects. Glutathione supplementation is thought to support this pool of glutathione present in cells and thus maintain the efficacy of the entire system. This supplementation can be even more important if chronic disease is seen as “drying up” this pool of antioxidant rich compounds. Free radicals and toxins can be a byproduct of many different things such as exercising or poor physical health, eating, and daily unhealthy lifestyle activities to name a few. When these molecules overcome the body at the cellular level, this constant barrage can have negative impacts on health and overall wellness. This overabundance of oxidative stress can contribute to pathogenesis of many liver diseases, as well as exacerbate preexisting conditions. Setria® L-Glutathione provides a potent supply of antioxidants that bind these free radicals, which can help keep them from causing lasting damage. There have been some conflicting reports on whether oral glutathione supplementation was a viable way of increasing serum glutathione levels as opposed to intravenous methods. One long-term, randomized, placebo-controlled study on the effects of oral glutathione supplementation showed that dosages as low as 250mg of Setria® Glutathione were able to:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eIncrease whole blood levels of glutathione by 17%\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eIncrease levels of glutathione in erythrocytes (white blood cells) by 29%\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTUDCA (Tauroursodeoxycholic Acid)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTUDCA gets its acronym as being the taurine conjugate of ursodeoxycholic acid (UDCA), a secondary bile acid that is produced only by intestinal bacteria. UDCA was originally FDA approved for the treatment of certain cholestatic liver diseases based on its ability to protect hepatocytes (liver cells) from hydrophobic bile acids. Cholestasis occurs when bile acids get backed up in the liver and there is room for metabolism. These bile salts can be damaging to the cell membranes of nearby tissues, in particular liver tissues, and can begin to signal for cell death (apoptosis). TUDCA works through a mechanism of action that shows its ability to inhibit liver cell apoptosis by interfering with the mitochondrial pathway of cell death, inhibit oxygen-radical production, and reduce endoplasmic reticulum stress. The endoplasmic reticulum acts as a highway between the nucleus of a cell and the cytoplasm and is heavily involved in protein and lipid synthesis. Through this reduction in ER stress, TUDCA has garnered a reputation as being a beneficial remedy for a wide range or metabolic diseases, and for being a neurological protection agent. Although TUDCA has been shown to possess wide ranges of benefits, its most common and practical use has continually been seen in the ability to provide protection and overall health for the liver.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBioperine® (Black Pepper Extract) (Piper nigrum) (fruit) (std. 95% piperine)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBioPerine® is a patented standardized extract from the fruit of Piper nigrum (black pepper). It’s studied benefits have continually shown improvements in bioavailability of nutrients it is surrounded by. When it comes to post exercise nutrition, efficiency and speed with which nutrients can enter the system and get to their target is of the upmost importance. The “window of opportunity” is much larger than what has been previously thought, but when your results weigh heavily on post-exercise nutrition, maximal absorption and use of nutrients is extremely important.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":42080551010546,"sku":"coreliver","price":54.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/core-productsliver1_1800x1800_0a205728-d05a-47bf-96b0-7aa6890d0592.jpg?v=1637382113"},{"product_id":"core-heart-support","title":"Core Heart Support","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutritionals Heart Support\u003c\/h2\u003e\n\u003cp\u003eEvery set, rep and mile, every breath, even your thoughts - ultimately every single one is driven by your heart. As the body’s engine and delivery system, no one escapes the undeniable need for a healthy cardiovascular system. For the driven athlete - such as those living the Crush It lifestyle - the aggregation of marginal gains provided by improving your cardiovascular health promises to elevate performance throughout your fitness regimen.\u003c\/p\u003e\n\u003cp\u003eAnd yet, few list improving cardiovascular function as a key priority within their fitness goals. You see, while the heart occupies the kind of rarified air reserved for central components of only the most vital bodily systems, its function is involuntary, its improvements invisible. You don’t have to think about beating your heart, it is done for you. What’s more, a well-maintained, highly trained heart muscle won’t get you noticed at the beach.\u003c\/p\u003e\n\u003cp\u003eThat said, however, our heart is one of the most important organs in the body and communicates, assists or supports literally every other major organ system. Without an efficient blood supply, your lungs will provide less oxygen to the muscles and access to key nutrients is reduced throughout the body, resulting in less effective workouts and suboptimal recovery. So, due to our passion for fitness, as well as our desire to help our customers improve and actualize their fitness goals, we've developed a clinically backed formulation for our new premier cardiovascular health supplement: Core HEART.\u003c\/p\u003e\n\u003ch3\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eCore Nutrition Heart Support Highlights\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHawthorne Berry Extract\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- blood vessel antioxidant support.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBergamot\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- healthy cholesterol support.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResveratrol\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- enhanced overall cardiovascular function\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003e\u003cmeta charset=\"utf-8\"\u003eCore Nutritionals Heart Support Supp Facts\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eZinc (as Zinc Bisglycinate Chelate TRAACS®)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eZinc is an essential micronutrient and mineral that has been shown to affect the heart by modulation of cardiomyocyte oxidative stress and maintenance of myocardial structure. When cross sectional studies have been conducted, zinc deficiency has frequently been found to be a common link in those who have suffered heart related traumas. Myocardial tissue requires zinc in small quantities to maintain the extracellular structure formed by matrix metalloproteinases and to serve as a cofactor in free radical oxidation reactions catalyzed by superoxide dismutase (an enzyme that helps break down potentially harmful oxygen molecules in cells. When chronic inflammation is present, plasma zinc deficiency may lead to a relative deficiency in antioxidant enzymes, ultimately contributing to apoptosis and myocardial necrosis. As the lack of cardio function and zinc levels tend to decline with age, ensuring zinc optimal zinc levels can be of an importance in maintaining cardiac optimal cardiovascular function as one ages\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin K2 (as MenaQ7®, Menaquinone-7)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAdequate intake of vitamin K2 has been shown to significantly benefit cardiovascular function. Lifestyles and eating habits in the traditional western diet can often contribute to an accelerated calcium deposit in blood vessel walls and soft tissues, which can lead to dysfunctional cardiovascular health. Calcium does serve many vital roles in the human body, such as muscle contraction, nerve signaling, blood clotting properties, and blood vessel contraction and expansion. It is also recommended in a supplemental form for those individuals who are suffering from bone related declines for support. So yes, calcium is beneficial for heart health and a wide variety of bodily functions. Where calcium can become less beneficial is when it is overconsumed and renders normal calcium concentrations in the blood ineffective. So, there is evidence to show that serum levels of calcium in the upper normal range increase risk of cardiovascular function declines due to elevated blood clotting and calcium deposition in blood levels.\u003c\/p\u003e\n\u003cp\u003eEnter, vitamin K2, which specifically has been shown to inhibit this arterial calcification and arterial stiffening through its ability to activate matrix GLA protein, which inhibits calcium from forming deposits on the vessel walls. Vitamin K2 also is essential for maintaining blood homeostasis, as well as optimal bone and heart health through its role in inducing calcium use by proteins. With vitamin K2 being almost non-existent in typical diets on the western part of the world (partly due to our traditional eating habits), supplementation can be crucial to lowering risk of cardiovascular function decline. One study conducted using supplemental Vitamin K2 showed that consistent use of small doses (specifically Mena Q7) were enough to improve bone mineral density, bone strength, and cardiovascular health through the mechanisms of action listed above. The increase of calcium usage for purposes of osteoblast usage, increasing arterial elasticity, and reduction in age related arterial stiffening make vitamin K2 an essential mineral for optimal cardiovascular function and health.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin D3 (as Cholecalciferol)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin D, in its various forms, is not an essential nutrient – as it is produced endogenously within the body, as a reaction to the skin’s exposure to the sun – and thus not commonly considered a vitamin. Despite its technical classification, vitamin D (a hormone), is nevertheless an import and biologically-active compound, necessary for the calcium homeostasis and metabolism, along with increasing the absorption of magnesium and phosphate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHawthorne Berry Extract (Crataegus oxyacantha) (fruit) (4:1)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHawthorne has been utilized for many centuries for its wide range of health benefits. One of these primary benefits is how it positively affects the cardiovascular system. The berries, or fruit, of the plant contain high amounts of bioflavonoids and proanthocyanidins, substances shown to contain most of the health promoting qualities. These antioxidants have several mechanisms of action on the cardiovascular system. Hypotensive (lowering blood pressure) improvements can be seen through vasorelaxation through the stimulation of nitric oxide production. Several studies have investigated this benefit on blood pressure as well. One human study conducted on individuals with high blood pressure showed that the administration of 1200mg of Hawthorn Berry (slightly more than what we use in this product), noticed substantial improvements in blood pressure when compared to placebo.\u003c\/p\u003e\n\u003cp\u003eHawthorne Berry can also play a role in preventing atherosclerosis, or a buildup of plaque in the blood vessels that occurs due to an imbalance in blood fat levels (typically high triglycerides and low HDL cholesterol). If this plaque continues to accumulate, it can lead to blockages in the blood vessels carrying blood to vital organs, ultimately resulting to heart attack or stroke. Anti-atherosclerotic improvements can be seen through the downregulation of capsase-3 gene expression. The capsase-3 gene is known for being a proapoptotic (cell killing) gene that has been reported in heart failure and myocardial infarction (heart attack). The regulation of lipoprotein lipase (regulates the delivery of fats to body tissues) expression and raised excretion of bile acids can also benefit the arteries. Several animal studies have examined the positive impact of Hawthorne Berries on cholesterol. One study on mice showed that mice given the extract resulted in a lower total and LDL cholesterol, as well as between 30-45% lower liver triglyceride levels compared to mice that were not administered the extract.\u003c\/p\u003e\n\u003cp\u003eOn cardiac cells, these antioxidants downregulate capsase-3 gene expression and inhibit 3’,5’-cyclic adenosine monophosphate phosphodiesterase, which can result in an increase in coronary flow, increase in relaxation velocity, and cause a positive inotropic effect (increase the strength of heart muscle contraction).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOlive Extract (Olea europaea) (leaf) 20% Oleuropein)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOlea europaea, more commonly known as the olive, is a species of a small tree in the family Oleaceae, native to the coastal areas of southeastern Europe, western Asia and northern Africa, as well as northern Iran at the south end of the Caspian Sea. As the fruits, oils, and extracts of Olea europaea L. are a dietary component for a significant portion of the world’s population, the plant has become associated with a wide-range of physiologic and metabolic benefits. These properties are largely attributed to the phenolic compounds of olive leaves, including: caffeic acid, verbascoside, oleuropein, luteolin 7-O-glucoside, rutin, apigenin 7-Oglucoside, and luteolin 4′-O-glucoside. Collectively, these olive polyphenols are responsible for a wide-range of postulated health benefits.\u003c\/p\u003e\n\u003cp\u003eOleuropein, in particular, is purported to have several pharmacological properties including antioxidant, anti-inflammatory, anti-atherogenic, and anti-microbial effects. Research shows that olive leaf extract can benefit the heart by helping to prevent LDL cholesterol from building up in the arteries. This process can increase blood flow and lower blood pressure, which can thus reduce the risk of heart disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRed Yeast Rice (Monascus purpureus)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRed yeast rice is traditional Asian preparation of the rice grain with an extensive history dating back to 300 BC. The rice is fermented in a culture of yeast called Monascus purpureus, which transfers in bright red coloration to the white rice grains. In part due to its centuries of use in traditional Chinese medicine, red yeast rice is widely recommended in regimens intended to help establish normal cardiac function and lipid profiles.\u003c\/p\u003e\n\u003cp\u003eMore recent studies suggest the fungal metabolites found within red yeast rice demonstrate a positive impact on cholesterol and cardiac function. Specifically, a fungal secondary metabolite found within red yeast rice, known as monacolin K, has been shown to of particular interest. The primary mechanism of action of monacolin K is inhibition of the key enzyme, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, involved in cholesterol synthesis. Upon further evaluation of the lipid lowering properties of red yeast rice, recent research revealed them to be multifactorial, including the ability to downregulate the rate limiting step of hepatic cholesterol biosynthesis in a dose-dependent manner, indirectly cause an upregulation or availability of LDL-receptors in the liver, and possibly increase the hepatic excretion of bile acids, thereby creating an increased need for the availability of intrahepatic cholesterol for use in the synthesis of additional bile. The reduced intrahepatic cholesterol concentrations result in the upregulation or availability of LDL-receptors in the liver. The purpose of these additional LDL-receptors is to pull cholesterol out of circulation and bring it into the liver as a replacement for the reduced production inside the liver. When this happens, the plasma cholesterol levels will decrease through a reduction in the hepatic synthesis of cholesterol and through an increase in the removal of circulating cholesterol from blood plasma into the liver for use. These actions can help restore cholesterol levels to where they benefit cardiac and other bodily function.\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003eNote: If you are taking other statins or other cholesterol lowering medication, please consult with your physician prior to supplementing with Core HEART.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBergamot Fruit Extract (Citrus aurantium bergamia) (30% Polyphenols)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBergamot, a citrus fruit native to southern Italy, has often been used to improve immunity and cardiovascular function. These benefits have been traced back to the phytochemicals and flavonoids that are contained within bergamot. Multiple studies have been conducted to show the efficacy of orally administered bergamot on reductions in total cholesterol and LDL cholesterol 1, where the end goal is the restoration of overall cardiovascular function and vessel health. The primary mechanism of action for the therapeutic phytochemicals found within bergamot is the inhibition of oxidation of low-density lipoprotein particles. When oxidation occurs to LDL particles, it produces a harmful form of cholesterol because of the damage caused by free radicals. This oxidative damage has been specifically linked to altered cardiovascular blood flow and cardiovascular vessel diseases. Phytochemicals such as naringin, neoeriocitrin, and rutin have been shown in vitro to possess antioxidant properties and ability to lower the oxidation of LDL particles.\u003c\/p\u003e\n\u003cp\u003eIn addition to the animal studies, several human trials have been conducted analyzing the benefits of bergamots. One 2011 randomized, double blind, placebo controlled clinical trial looked at the impact of bergamot administration for 90 days on total cholesterol, LDL levels, and HDL levels in patients. The results showed that 500mg of bergamot reduced total cholesterol (20%) and LDL (23%), while increasing HDL levels (26%). This is just one example but results of other studies show promise in bergamot’s cholesterol improving benefits as well as optimizing overall cardiovascular function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCurcumin (Curcuma longa) (root) (95% Curcuminoids)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTurmeric is a root endemic to certain regions of Southeast Asia and India, and has been a staple in the Siddha traditional medicinal system for thousands of years. Turmeric is noted in Siddha texts for various uses, including as an ancient equivalent of an anti-microbial agent.\u003c\/p\u003e\n\u003cp\u003eMore recently, numerous studies seem to suggest that its primary bioactive constituent, curcumin, powerfully inhibits the enzymes that synthesize inflammatory compounds such as prostaglandins and leukotrienes. In particular, basic research and molecular studies have now firmly established curcumin’s ability to dose-dependently and potently inhibit a transcription factor known as NF–kB – a molecule involved in the proliferation of pro-inflammatory cytokines, soft tissue destruction, and autoimmune responses.\u003c\/p\u003e\n\u003cp\u003eThough turmeric contains approximately 5% curcumin by weight, we have used a highly standardized extract of 95% - recognizing that the wealth of research on curcumin demands that it be included in clinical serving sizes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePolygonum cuspidatum Extract (root) (50% trans-Resveratrol)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eResveratrol is a polyphenolic stilbene produced by various plants. Trace amounts of resveratrol can be obtained from certain foods but the clinical doses used for studies involving cardiovascular function are at much higher concentrations than can be likely received through dietary means. While the half life of resveratrol is relatively low (4-8 hours) after oral administration, a large number of animal studies have shown beneficial effects for cardiovascular function. The specific mechanisms of action for resveratrol are somewhat unclear, but studies have shown many positive benefits tracing back to decreases in oxidative stress response, increases in endothelial function, leading to more efficient diastolic function, cardiac remodeling, myocardial energetics, and vascular function. The proposed mechanism for the inflammation mediating effects can be brought back to an increased activation of the silent information regulator factor 2 related enzyme 1 (SIRT1). SIRT1 has been shown to protect against cardiac decline related inflammation. When studied, cells from mice with a SIRT1 knockout have shown increased pro-inflammatory cytokine levels. With resveratrol being a known activator of SIRT1 in animals, it is led to believe that the same mechanism can be beneficial in humans. This mechanism, along with other benefits on blood pressure (increased NO production), make resveratrol a valuable compound in establishing normal cardiac function and baselines of cardiac health.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoenzyme Q10 (Ubidecarenone)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCoenzyme Q10, which is synthesized in the mitochondrial inner membrane, is an essential compound that plays many vital roles in the human body. Of these many roles, it is a key component in the electron transport chain in mitochondria necessary for ATP production. CoQ10 can also act as an intercellular antioxidant, protecting the plasmatic membrane against peroxidation. CoQ10 deficiency has been associated with less-than-optimal health status in organisms and has contributed to certain degenerative states involving blood sugar, the cardiovascular system, and musculoskeletal system. In relation to the cardiovascular system, oxidative stress is one of the main causes of cardiac decline. The antioxidant properties of CoQ10 are of particular importance in establishing normal function. It has been shown that individuals suffering from cardiac related abnormalities have significantly lower levels of CoQ10 as opposed to those with higher levels. With antioxidant effect and free radical neutralization being the primary mechanism of action, CoQ10 exhibits a secondary mechanism of action of well in playing a large role in the heart’s energetic needs. The process of cardiac contraction requires the release of Ca2+ from the SR and the following activation of the contractile proteins requires energy. It is believed that when there is myocardial failure, it is caused by a reduction in the production of energy from the mitochondria. This goes back to CoQ10s property of being a main component in the transport of electrons that are needed for ATP production. These two mechanisms of action have a particular importance for one’s quality of life as well as in maintaining proper cardiovascular function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBioperine® (Black Pepper Extract) (std. to 95% Piperine)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBioPerine® is a patented standardized extract from the fruit of Piper nigrum (black pepper). It’s studied benefits have shown improvements in bioavailability of nutrients it is surrounded by. In this specific product for Core HEART, it is included because it dramatically increases the bioavailability of curcuminoids (see above). Without Bioperine, the serum concentration and absorption rates of the active agents in curcumin would be significantly reduced.\u003c\/p\u003e\n\u003cp\u003eBioPerine® primarily works through mechanisms and channels that can inhibit intestinal motility and dilate blood vessels of the intestines (where absorption of nutrients occurs). This physiological action may cause increased absorption and digestion of nutrients.\u003c\/p\u003e\n\u003cp\u003eSeveral studies looking at the impact of BioPerine® on nutrient absorption have been done. One study looking at the efficacy of BioPerine® on serum concentrations of curcumin showed bioavailability was improved by more than 500%. Therapeutic effectiveness of curcumin has often been exhibited as low. Another study conducted over the course of 6 weeks on BioPerine® influence on serum selenium levels in humans showed an increase by 145% over the presupplementation value.\u003c\/p\u003e\n\u003cp\u003eWith promising research being done on the effects of BioPerine® in the context of nutrient absorption and bioavailability, it is only fitting that we include it in Core HEART.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":42080573522162,"sku":"coreheart","price":54.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/core-productsheart1_1800x1800_fda3ad4b-29ae-4423-8ab2-c620a11a80fb.jpg?v=1637382261"},{"product_id":"core-prostate-support","title":"Core Prostate Support","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutritionals Prostate Support\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eIt is critical to maintain healthy, normal prostate function. As men age, maintaining this function becomes more difficult, at which point a robust supplement regimen can assist in promoting proper prostate health. Many supplements on the market now focus on single ingredients, ignoring that prostate health is a multi-faceted problem that requires a multi-faceted solution. In typical Core Nutritionals style, we scoured the research to find a constellation of ingredients that address every major pathway of prostate health. We are supremely confident that Core PROSTATE is the premier solution in maintaining normal, proper prostate health.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eCore Prostate Support Highlights\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eSaw Palmetto Extract\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- aims to maintain healthy prostate size.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStinging Nettle Extract\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- normal and healthy urinary flow and frequency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLycopene\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- contributes to normal prostate function.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Prostate Support Supp Facts\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePumpkin Seed Oil Powder (Cucurbita pepo)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePumpkin seed has been used in the medical treatment realm for decades, especially for its noted benefits towards prostate health improvement. The fatty acids contained in pumpkin seeds, especially delta-7-sterols, tocopherols, and other micronutrients have shown specific promise in optimizing normal prostate function. A 2014 randomized, double-blind, placebo-controlled study looked at the effects of different administrations on subjects. Subjects were split and received either sweet potato starch, pumpkin seed oil, saw palmetto oil, and pumpkin seed oil with saw palmetto oil. What the results showed was that the group given pumpkin seed oil noticed improvements in quality of life and improvements in maximal urinary flow. These same improvements were also shown in the combined pumpkin seed oil and saw palmetto oil group making them both reputable complimentary products that can benefit the health of the prostate.\u003c\/p\u003e\n\u003cp\u003eOne of the primary mechanisms of action for pumpkin seeds is to block the conversion of testosterone to dihydrotestosterone, inhibiting the enzyme 5-α-reductase. Dihydrotestosterone is classified as a powerful metabolite of testosterone with critical functions as an androgen. While androgens can be beneficial for men, when they get too high, they can negatively affect certain parts of the human body, including the prostate, leading to issues such as less than optimal prostate function. Maintaining normal levels of dihydrotestosterone in the prostate is therefore a paramount property to maintaining the normal function of the prostate.\u003c\/p\u003e\n\u003cp\u003eZinc is also critical to normal prostate function. In fact, a normal functioning prostate has the highest levels of zinc in the body. A 2011 human study found an increase in urinary zinc excretion. Pumpkin seeds are naturally high in zinc, leading to their consumption could be beneficial to extract their prostate health improving properties.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSaw Palmetto Extract (Serenoa repens) (fruit) (85% Total Fatty Acids)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSaw Palmetto is a traditional herb that grows in the Southern coastal regions of the United States that has been often used to maintain normal, healthy prostate function. Growth of the prostate is believed to happen through the action of 5α-reductase, which catalyzes the conversion of testosterone to dihydrotestosterone. Dihydrotestosterone binds to nuclear androgen receptors and activates the transcription of androgen-regulated genes that are mitogenic to both epithelial and stromal cells. Due to the fact that the development and growth of the prostate gland depend on androgen stimulation, the mechanisms of action of saw palmetto include several antiandrogenic effects, such as inhibition of 5α-reductase I and II and inhibition of binding of dihydrotestosterone (DHT) to the cytosolic androgen receptors, anti-proliferative effects and anti-inflammatory effects. Several studies have shown that saw palmetto, and the mechanisms of action listed above may positively influence the prostate by helping to maintain its optimal size and function, which then equates to a healthy urinary flow and frequency.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStinging Nettle Extract (Urtica dioica) (root) (20:1)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStinging nettle has been widely used is traditional medicine for its benefits as a diuretic and to treat things like joint pain, eczema, arthritis, gout, and anemia. More recently, stinging nettle has been utilized for the purpose of maintaining normal urinary flow and contributing to a healthy, optimal functioning prostate. Stinging nettle has also showed effectiveness when used in combination with other herbs, like saw palmetto (above). Human studies have shown this effectiveness in these areas, like urinary flow maintenance, through their specific mechanisms of action, which were discussed in the paragraph above. The mechanism of action for stinging nettle is still somewhat unclear but it seems likely that sex hormone binding globulin (SHBG), aromatase (the key enzyme in estrogen biosynthesis), epidermal growth factor and prostate steroid membrane receptors are involved in the anti-prostatic effect. While the mechanism of action may be unclear at the present moment, the success of stinging nettle in human studies makes it a promising application for maintaining normal prostate health and function.\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cp\u003eInduce G1\/S arrest of the cell cycle\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003eInduce apoptosis\u003c\/li\u003e\n\u003cli\u003eInhibit angiogenesis Regulate sex hormones and\u003c\/li\u003e\n\u003cli\u003eIncrease antioxidant activity\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003ePygeum Bark Extract (Pygeum africanum) (3% Phytosterols)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe bark of Pygeum africanum, also known as the African prune tree native to tropical Africa, is a compound that has often been utilized for its benefits in maintaining prostate health. The mechanism of action for pygeum remains somewhat unclear. Studies utilizing pygeum bark have also shown promise in their benefits in support the maintenance of prostate health both in vitro and in vivo. In one in vitro study in particular, results showed that pygeum bark extract was able to inhibit the growth of PC-3 and LNCaP cells, as well as induce apoptosis and altered cell kinetics, and downregulated ERalpha and PKC-alpha protein. In vivo, utilizing TRAMP mice, the application of pygeum bark extract showed a significant reduction (35%) in prostate cancer incidence compared to mice fed another substance. Another analysis looking at 18 randomized controlled trials looked at the how pygeum africanum benefitted men and prostate health. Pygeum was shown to provide a large improvement in urinary function and flow measures when compared to other men in the study not administered pygeum. Men using pygeum africanum also noticed nocturia was reduced by 19%, residual volume of urine reduced by 24%, and peak urine flow increased by 23%. These results leave pygeum administration as a potentially beneficial application for those looking to maintain normal prostate function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBeta-Sitosterol (40%)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eβ-sitosterol is the most abundant plant sterol in the human diet and is also the major component of several traditional medicines, including saw palmetto and devil’s claw. It is believed to help maintain prostate function by aiding in the and ease of urinary flow. A few studies have been conducted on BS effectiveness on urinary system function and flow with promising results. One randomized placebo-controlled study on men showed promising results on these issues. Results revealed that men administered β-sitosterol noticed a more efficient flow measure and increased prostate function. While β-sitosterol can benefit from more studies, the current studies show promise and ability to work in synergy with the other components of Core’s comprehensive prostate funtion formula.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLycopene (Lycopersicon esculentum) (fruit)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLycopene, a carotenoid found largely in tomato, pink grapefruit, and watermelon, is a natural and effective nutrient that has been able to show ability in supporting optimal prostate function. Several studies have been conducted showing lycopene’s effectiveness in maintaining this prostate function in both in-vivo and in-vitro conditions. Results of these studies showed that lycopene was able to inhibit prostatic IGF-I signaling, IL-6 expression, and androgen signaling. Lycopene was also able to show improvements in gap-junctional communication and oxidative defense genes, which can be essential for maintaining prostate function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBoron (as Albion® Boroganic Glycine)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBoron is a mineral present in multiple fruits, vegetables, tubers, and drinking water, though it is not widely accepted as either an essential mineral or essential vitamin. Boron affects a few physiological functions in the body, particularly modulating hormonal homeostasis.\u003c\/p\u003e\n\u003cp\u003eWhile still emerging, recent data suggest that boron may play a role in potentiating free testosterone levels in healthy men. In one study, otherwise healthy men were provided an acute serving of boron and had their free and total levels of testosterone, alone with SHBG (sex hormone binding globulin) and DHT (dihydrotestosterone) levels measured. In that study, total testosterone was unaltered, but free testosterone was enhanced by 14%, while SHBG was significantly (9%) reduced. Boron has also shown substantial evidence in playing a role in supporting normal prostate function, specifically through lowering PSA (prostate specific antigen), which can be a marker for prostate abnormality advancement. Other studies have shown the effectiveness of adequate boron levels on optimizing prostate health. One human study concluded that men who ingested the greatest amount of boron in their diet were 54% less likely to be at risk of prostate related issues when compared to the lowest intake.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":42080595509490,"sku":"coreprostate","price":54.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/prostate1_1800x1800_505e0742-9407-42b3-b296-50298a65a205.jpg?v=1637392822"},{"product_id":"core-fury-australian-edition","title":"Core Fury Australian Edition","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003ch2 style=\"text-align: center;\" data-mce-fragment=\"1\"\u003eCore Nutrition Fury Australian Edition\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCore FURY Australia is a mixture of key ingredients that enhance athletic performance and increase mental edge. For athletic performance, Creatine Magnapower™, l-citrulline, betaine anhydrous, S7®, and beta alanine are included at, or above, serving sizes suggested by the research.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCollectively, these ingredients have been repeatedly demonstrated to increase maximum voluntary contractile force and other measures of power output, increase maximal oxygen uptake capacity, and significantly enhance time measures in standard athletic trials. For cognitive capacity, clarity, and focus, caffeine anhydrous, citicoline, and ZümXR are also included at, or above, serving sizes suggested by the research.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTogether, our performance and focus ingredients constitute the pinnacle of pre-workout formulas that earns a well-deserving spot amongst the pantheon of Core Nutritionals FURY™ products.\u003c\/p\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003eCore Fury Australia Supp Facts\u003cbr\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eL-Citrulline\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCitrulline is a non-essential, non-protein amino acid that forms during the urea cycle and forms ornithine when combined with carbon dioxide. Citrulline is also a critical source of endogenous (natural) arginine, as it is rapidly and efficiently converted to arginine in the vascular endothelium and other tissues\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCitrulline’s benefits have been shown to be greater than its parent compound. While arginine undergoes direct hepatic (liver) metabolism through the enzyme arginase, citrulline bypasses hepatic metabolism entirely and it is delivered straight to the bloodstream. The result is that gut absorption and plasma (blood) bioavailability studies comparing citrulline and arginine have shown two things. First, that citrulline is less readily destroyed and has greater absorption than arginine. Second, that citrulline supplementation increases arginine levels more effectively than arginine supplementation itself.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eBeta Alanine\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCarnosine is a bit of an odd duck: we know that it is crucial for muscle function, and that dietary sources of carnosine are essential, but we don’t know precisely how it’s working. Moreover, for decades, we had no idea how to increase intramuscular concentrations, as exogenous carnosine sources degraded in the body so fast as to be effectively useless.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eEnter beta-alanine. Simply a different iteration of one of the amino acids that comprises carnosine itself (alanine), beta-alanine has proven to be the most effective means of significantly increasing intramuscular concentrations of carnosine – and therefore of promoting all of carnosine’s various beneficial effects on muscle performance. If that weren’t enough, beta-alanine has also demonstrated beneficial physiological effects independent of its parent compound. In order to understand why, though, we need to first understand some of the basics behind carnosine itself.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCarnosine, a cytoplasmic dipeptide synthesized from the precursors L-histidine and l-alanine, is present in high concentrations in skeletal muscle and plays a pivotal role as a, “chemical buffer” in myocytes (muscle cells). It has long been known that carnosine concentrations are highest in glycolytic, rather than oxidative muscle fibers (roughly speaking, explosive vs., endurance muscle fibers, respectively), and thus long hypothesized that this amino acid is required for sustained performance during supramaximal exercise. Recent research demonstrates that carnosine exerts its physiological effects in long hypoxic (low oxygen) drives by functioning as a high-capacity pH buffer in skeletal muscle, preventing the pH ratio of plasma from dropping too low – and therefore preventing crucial pH-dependent processes such as protein synthesis from being inhibited by acidosis.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eBetaine Anhydrous\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eBetaine (trimethyl glycine) is found naturally in most living organisms. It is well known to protect non-mammalian animal life in conditions of osmotic stress (a rapid change in the amount of solute surrounding a cell), in addition to functioning as an osmolyte in mammalian (including human) tissues. Betaine is formed in cells as an oxidation product of choline and can be obtained in the diet from foods such as spinach and beets.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThough data on betaine is limited, and recent, the available literature suggests that this compound may have effects in a few areas. Studies on betaine using servings as little as 1.25g\/day and up to 5g\/day for up to 14 days have shown promising results. In one study, a 2.5g\/day serving was found to enhance endurance and total repetition volume for the squat, bench press, and jump squat in in healthy-exercised trained adults. A similar study using the same serving found that betaine use increased peak power and maximum peak power, along with force and the maintenance of both force and power in healthy, exercise-trained subjects.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eL-Tyrosine\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTyrosine is amongst a class of amino acids known as ‘non-essential’ amino acids, so called because the body can produce them endogenously, and it is therefore not essential to consume dietary tyrosine. That said, tyrosine is also what is known as a conditionally-essential amino acid; conditionally-essential because, along with glucose and ammonia, the synthesis of tyrosine additionally requires adequate levels of phenylalanine. Once synthesized, tyrosine is one of the most critical amino acids, given its prominent role as a substrate in the synthesis of the catecholamines dopamine, norepinephrine, and epinephrine, in addition to both T3 (triiodothyronine) and T4 (thyroxine) thyroid hormones.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIn studies on stress modulation, tyrosine has been demonstrated to reverse stress-induced norepinephrine depletion and the depressant-behavioral effects normally associated with it. In simpler terms, tyrosine may, in certain conditions, dampen the extent to which norepinephrine is removed from the bloodstream during a stress event. In simpler terms still, tyrosine may help to mitigate the sense of depletion and fatigue felt at the end of a workout.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTyrosine may also play important metabolic functions, mostly related to its role in synthesizing compounds which stimulate the nervous system. While not traditionally considered a sympathomimetic amine, studies which have coadministered tyrosine and stimulants demonstrate a synergistic effect. These studies suggest that tyrosine may potentiate the effects of both endogenous and supplemental norepinephrine and its mimetics (in the case of exogenous use) with respect to lipolysis, thermogenesis, and energy expenditure. Meaning that tyrosine may play a role in assisting norepinephrine to break up triglycerides and increase body heat transiently.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eCreatine MagnaPower® Magnesium Creatine Chelate\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSometimes called the “grandfather” of dietary supplements, creatine is, along with caffeine, one of the most extensively studied dietary compounds. Certainly, it is the most well-studied ergogenic aid. Generally speaking, the extensive amount of data on creatine demonstrates that it positively contributes to dilation of the vasculature, plasma-nutrient mobilization, post-workout nitrogen retention and protein synthesis, along with dose-dependently increasing contractile force through ATP (adenosine triphosphate) provision (i.e., it helps support increased strength).\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCreatine MagnaPower® is a unique combination of creatine and magnesium chelate that has been shown to enhance the absorptive properties of creatine into the target muscles. So, this allows for creatines ATP (adenosine triphosphate) replenishment capabilities to be dramatically enhanced. As a reminder, ATP is currency for your body to utilize for every cellular process. Without this currency, the cell will run dry and function will decline. The increased absorption is due to magnesium’s strong alkaline properties. During normal creatine absorption, a reaction takes place called the lactamation reaction, which reduces the bioavailability of creatine. The magnesium that is contained in MagnaPower acts as a buffer to this reaction and allows for more creatine to be available in the muscle cell. With Creatine MagnaPower® showing the ability to produce larger quantities of ATP, this means that muscle fiber contractions are able to be more forceful and happen more often, which is an excellent combination for increases in muscle mass and strength at a more efficient rate.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eVasoDrive-AP®\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eVasoDriveAP® is a proprietary ingredient derived from fermented casein. The fermentation process produces two lactotripeptides, Valyl-Prolyl-Proline (VPP) and Isoleucyl-Prolyl-Proline(IPP). Based on the available clinical evidence, these tri-peptides work together to reduce angiotensin converting enzyme (ACE).\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIn a recent meta-analysis researchers found 30 studies – all of which were randomized and some of which were double-blind – wherein Valyl-Prolyl-Proline (VPP) and Isoleucyl-Prolyl-Proline (IPP), either alone or in combination, exerted a statistically significant effect on improving endothelial function. In one of the analyzed studies, 25 men were challenged with casein hydrolysate standardized for tri-peptides in a randomized and placebo-controlled design. At the conclusion of the study, forearm blood flow, a key measure of endothelial function, was found to be increased by 33%. The researchers in this and other studies demonstrate that the tri-peptides that constitute VasoDriveAP® exert an inhibitory effect on ACE. ACE, in turn, is a critical component of the renin-angiotensin (RAS) system, which regulates hemodynamics by controlling plasma fluid volume. While the precise mechanism has not been elucidated, researchers believe that the lactotripeptides in VasoDriveAP® competitively inhibit ACE, thus decreasing the metabolism of bradykinin and systematically dilating the arteries and veins.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eCaffeine Anhydrous\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCaffeine is one of the most widely consumed, and perhaps one of the most reviewed, psychoactive compounds. Its physiological effects in a range of areas have been well-documented, including exercise performance, information processing, alertness and mood enhancement, attention, and awareness, along with its anti-lipogenic and lipolytic abilities.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eMost importantly to Core FURY, caffeine has been shown to have significant effects on exercise performance, even with ingestion in servings as small 3 to 9mg\/kg\/bw\/day (the equivalent of 2 cups of standard coffee, for a 170lb male). In endurance training, possible explanations for caffeine’s performance-enhancing effects lie in its metabolic effects on both lean and fat tissue. It is suggested that caffeine’s potent lipolytic (the breakdown of fat tissue into fatty acids) and oxidative (the actual ‘burning’ of fat) action allow the body to utilize these sources during prolonged submaximal exercise. As a consequence, muscle glycogen is spared and available for use later in the training session. Practically speaking, this means caffeine is forcing your body to preferentially use fat tissue as a fuel source, while sparing the glycogen which gives you the full-bodied look!\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIn short-term exercise, caffeine’s demonstrated role in the inhibition of cyclic AMP- phosphodiesterase’s (PDE), adenosine receptor antagonism, and adrenoreceptor agonism come into play. These three pathways collectively stimulate lipolytic activity, boost fat metabolism, increase metabolic rate and energy expenditure, and regulate the body’s thermogenic activity. The practical results of activating these pathways are increases to the contractile force of both cardiac and skeletal muscle (harder flexion), an increase in energy expenditure (freeing up more caloric energy to be used in contraction), dilation of vasculature (better blood flow), and improvements to both nitrogen retention and skeletal muscle protein synthesis (key components to muscle building).\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eCiticoline (Cytidine 5′-diphosphocholine)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCholine is an essential nutrient involved in numerous metabolic pathways, including DNA regulation and repair, protein function, and metabolism. Perhaps most importantly, the critical neurotransmitter acetylcholine is produced directly from free choline via cholinergic neurons. Acetylcholine is then responsible for several functions itself, most crucially as the compound which induces muscular contraction, and as the neuromodulator partially responsible for modulating risk\/reward, arousal, and enhancing memory.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCholine’s essential role as a substrate for acetylcholine, and therefore brain development, is well documented in animal models. These studies demonstrate that levels of free maternal choline have a direct and fundamental impact on prenatal brain development, with the enhancements or deficits lasting into adulthood. Choline’s enhancing effect is particularly prominent in the hippocampus. In humans, the hippocampus is primarily involved in the consolidation of memory (taking short, episodic memory and translating it into long-term memory) and the learning of new information. Acetylcholine is a critical component in these processes, as mentioned above, and choline may therefore play a potential role in these processes as well by providing the substrate for acetylcholine synthesis.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTartaric acid occurs naturally in the food source, while its salt derivatives (tartrate, for example) have been used as acidulants, antioxidant synergists, buffers and sequestrants. As free base choline is rapidly destroyed in metabolism, attaching a salt to enhance absorption is necessary. The bitartrate salt addition preserves choline from being destroyed during metabolism.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCDP-choline, or citicoline, is a cytidine molecule bound to a choline molecule via two phosphate groups (hence the diphosphocholine). The principal difference between standard choline supplementation as, say, choline bitartrate, and citicoline, is that citicoline is a cytidine supplier in addition. The combination of cytidine and choline in a single-source confers not only the direct effects of each ingredient on cognition and memory – but also factors significantly into choline biosynthesis\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eS7®\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eS7® is a low dose, but high power, blend of 7 (hench the name) plant-based components that have been clinically shown to increase nitric oxide (NO) production at extremely large amounts. These ingredients contain green coffee bean extract, green tea extract, turmeric extract, tart cherry, blueberry, broccoli, and kale. Some of the NO increases seen from this ingredient blend have been of upwards of 230%. This may not mean like much of an importance to the common individual, but to the individual who is serious about their training this can be extremely vital. Not only does nitric oxide act as a vasodilator, increasing blood flow to working tissues, it also aids in the delivery of oxygen and other key nutrients to active muscles during their use. This delivery of nutrients can also aid in recovery and decrease muscular fatigue, which will allow for more intensity during training session as well greater longevity during said training sessions. So how else does S7® work? It also works through a process called redox signaling modulation. Redox signaling molecules are produced naturally within our cells and are produced through the reorganization of H2O and NaCl molecules. Some of these messenger molecules roles are to defend other cells, repair damaged cells, or to replace damaged cells with healthier ones. This process serves as a first line of protection against the accumulation of oxidative stress and damage, much of which can be seen with intense training. Having healthy levels of redox signaling and the related oxidants has been hypothesized to be crucial for understanding optimal health. One double-blind, crossover, placebo-controlled study investigated this hypothesis and came to the conclusion that S7®, and its potent blend of antioxidant rich components, were able to positively affect cellular redox signaling and modulate certain inflammatory markers that can be detrimental to athletic progression.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eZüm-XR ® XR Caffeine (provides 50mg caffeine):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eZüm-XR is a patented coating technology that allows the dissolution profile of certain ingredients, primarily caffeine, to have a longer lasting affect in blood serum levels. The release of those ingredients is initiated by an abrasion in the stomach and pH levels between the stomach and the upper gastrointestinal tract. The coating of the microbead technology is a patented timing system with pharmaceutical grade safe polymers. Comparatively speaking, the dissolution profile of Züm-XR caffeine to your typical immediate release caffeine showed that Züm-XR took a far greater amount of time, well over 120 minutes to complete the process of dissolution.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong data-mce-fragment=\"1\"\u003eHuperzia serrata Extract (leaf and stem) (1% Huperzine A):\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHuperzia serrata is a compound found in the plant families of Huperziaceae, Lycopodiaceae, and Selaginella.and is endemic to China. The Lycopodium alkaloid Huperizin-A, found in Core FURY Australia, was first isolated from a folk medicinal preparation in 1984.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eDue to the potent anticholinesterase activities of Huperzine A, the compound was been evaluated in numerous in vitro, in vivo, and human trials. These data suggest that Huperzine’s Ache activities are most potent in the cortex, hippocampus, and striatum (at least in rats) – key regions in the brain responsible for forming, coordinating, and recalling memory. These effects are assisted by Huperzine A’s high oral bioavailability. Studies using microdialysis technique in rats, for example, showed that the response to Huperzine A was dose-dependent and substantially lowered the level of ACh in cortex.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"20 Servings \/ Lemon Lime Sherbert","offer_id":42224946348274,"sku":"coreauspre-1","price":54.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Green Apple Candy","offer_id":42224946413810,"sku":"coreauspre-2","price":44.95,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Australian Raspberry Chews","offer_id":42224946479346,"sku":"coreauspre-3","price":54.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/core-productslemon_1800x1800_acbe0276-7bbd-4504-906f-b6d4f78f2c6d.jpg?v=1640234644"},{"product_id":"puddn-protein-blend","title":"Core Pudd'n Protein Blend","description":"\u003ch2 style=\"text-align: center;\"\u003ePudd'n Protein Blend\u003c\/h2\u003e\n\u003cp\u003eThis mix of casein protein, whey concentrate, and milk protein isolate creates a robust and complete amino acid profile that has been shown in research to increase lean muscle growth.\u003c\/p\u003e\n\u003cp\u003eThis specific protein blend along with added coconut oil creamer creates an amazingly smooth and velvety texture. Then we added decadent confectionary inclusions that will explode with flavor in every bite. You’ll easily be thinking your cheating on your diet with this PUDDN.\u003c\/p\u003e\n\u003ch3\u003eCore Nutritionals Puddn Highlights\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eCasein Protein Blend:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eSlow absorbing protein with a velvety texture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDigestive Enzyme Blend:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eSupports healthy protein, carbohydrate, and fat breakdown.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConfectionary Inclusions:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eAdded burst of flavor and texture in every bite.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003ePudd'n Supp Facts\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eMicellar Casein\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCasein provides all essential amino acids, except cysteine, and has a high digestibility and bioavailability, making it a high-quality protein source to ingest.\u003c\/p\u003e\n\u003cp\u003eCasein exhibits a slow absorption and release of amino acids in to the body. This slow release contrasts the relatively efficient release of your standard whey protein concentrate. Due to this, casein has often been touted as the perfect “bedtime protein” so that the slow, yet steady release of amino acids can occur when the body is not in an active state for a lengthy period of time. The benefits of this allow for the body to remain satiated with amino acids through the night as well as increase muscle protein synthesis to maximize muscle recovery. Consumption of casein and whey protein before bed also has positive influence on the next morning resting metabolic rate. Several studies have demonstrated the positive benefits of consuming casein and post-exercise recovery. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCold Processed Undenatured Whey Protein Concentrate\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis process of cold processed undenaturization preserves the molecular structure of the amino acid particles as well as the immune boosting benefits that it contains. This undenatured protein is also a rich source of amino acids, including those needed for the synthesis of glutathione, which is an important antioxidant that can be depleted by stress (exercise stress included). This makes it a great foundation for your post workout recovery nutrition.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCoconut Oil Creamer\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCoconut oil made of 100% Medium chain triglycerides has been shown to have the greatest health benefits. MCTs are made up of a chemical structure that allows them to quickly and effectively bypass gastric uptake for transport directly to the liver for oxidation and then used for energy. Their unusual chemical structure and metabolic process has resulted in MCTs being a focus for a wide range of therapeutic and exercise supplement uses.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eMilk Protein Isolate\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis blend has been specifically configured to provide both rapid and sustained additions to your body’s amino acid profile – meaning your recovery is not only supported immediately after a session but will also carry you to your next meal. On top of that, our flavors are out of this world! We’ve also boosted this protein blend with digestive enzymes that will provide you with all of the confidence that those nutrients you just supplied your body with will do their part in your quest for the optimal result!\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eDigeSEB™ (Digestive Enzyme Blend: Amylases, Lactase, Proteases, Lipase, Cellulase)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese powerful little protein structures influence or outright control a vast, complex network of bodily functions. In a fitness-specific context, digestive enzymes play an absolutely crucial role in the breaking down of dietary carbohydrates, fats, and proteins into their constitutive parts, and therefore allow your body to use them in various processes (glycogenesis, protein synthesis, etc.).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eDigeSEB™ ensures that Core PUDDN not only provides gourmet taste and clinical ingredients within the protein itself, but that your protein also increases the effectiveness of your pre and post-workout nutrition in general.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"12 Servings \/ Banana PB Chocolate Chip","offer_id":48395976769778,"sku":"puddnprotein-12scphcc","price":39.99,"currency_code":"USD","in_stock":true},{"title":"12 Servings \/ Chocolate Chip Cookie Dough","offer_id":48395976933618,"sku":"puddnprotein-12scccd","price":39.99,"currency_code":"USD","in_stock":true},{"title":"12 Servings \/ Death By Chocolate","offer_id":48395977556210,"sku":"puddnprotein-12dbc","price":39.99,"currency_code":"USD","in_stock":true},{"title":"17 Servings \/ Cookie Dough Moose Tracks","offer_id":46473424503026,"sku":"puddnprotein-ccmoose","price":49.95,"currency_code":"USD","in_stock":true},{"title":"17 Servings \/ Original Moose Tracks","offer_id":44395759403250,"sku":"puddnprotein-ogmoose","price":49.95,"currency_code":"USD","in_stock":true},{"title":"17 Servings \/ Chocolate Moose Tracks","offer_id":44395759468786,"sku":"puddnprotein-chocmostrck","price":49.95,"currency_code":"USD","in_stock":true},{"title":"24 Servings \/ Rocky Road","offer_id":43524691165426,"sku":"puddnprotein-rr","price":49.95,"currency_code":"USD","in_stock":true},{"title":"27 Servings \/ Cookie Dough n' Cream","offer_id":43524691198194,"sku":"puddnprotein-cdnc","price":49.95,"currency_code":"USD","in_stock":false},{"title":"27 Servings \/ Fluffernilla","offer_id":43524691230962,"sku":"puddnprotein-fluff","price":49.95,"currency_code":"USD","in_stock":true},{"title":"27 Servings \/ Cookie Dough Moose Tracks (Best by 5\/26)","offer_id":49635055173874,"sku":"puddnprotein-ccmoosemd","price":34.96,"currency_code":"USD","in_stock":true},{"title":"27 Servings \/ Fluffernilla (Best by 6\/26)","offer_id":49635064316146,"sku":"puddnprotein-fluffmd","price":34.96,"currency_code":"USD","in_stock":true},{"title":"24 Servings \/ Rocky Road (Best by 2\/26)","offer_id":49635065463026,"sku":"puddnprotein-rr","price":25.0,"currency_code":"USD","in_stock":true},{"title":"17 Servings \/ Chocolate Moose Tracks (Best by 2\/26)","offer_id":49635065823474,"sku":"puddnprotein-chocmostrckmd","price":25.0,"currency_code":"USD","in_stock":true},{"title":"17 Servings \/ Original Moose Tracks (Best by 2\/26)","offer_id":49635066216690,"sku":"puddnproteinogmstrcks","price":25.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/PUDDNP_BCPBC_FRONTLarge.jpg?v=1764490953"},{"product_id":"core-longevity","title":"Core Longevity","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Longevity\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCore Lifeline’s LONGEVITY is designed to help keep your mitochondria functioning properly and protect against further damage through the inclusion of intensively researched ingredients such as Quercetin, BIONMN®, and Puremidine®, among others, at or above recommended dosages. Extend your health and performance today with LONGEVITY!\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuercetin Anhydrous 95%\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eQuercetin is often classified as a key flavonoid that is present in a wide variety of fruits and vegetables traditionally known for its high antioxidant and inflammation reducing properties. Recently however, quercetin has been shown to exhibit benefits outside of its free radical-scavenging properties. These newly seen benefits have put emphasis on quercetins ability to effect mitochondrial processes in vitro. These benefits have been seen through modulation of mitochondrial biogenesis pathways, mitochondrial membrane potential, oxidative respiration and ATP anabolism, and mitochondria induced apoptosis.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eWhat are mitochondria?\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eMitochondria are complex and multifunctional organelles engaged in almost all cellular processes. They are commonly referred to as the “powerhouse” of the cell due to their role in the breakdown of carbon-rich fuel molecules (glucose, lipids, glutamine) and in ATP synthesis via oxidative phosphorylation. So not only do mitochondria help turn energy we take in from food into useable cellular energy, they also play other vital roles in the human body to maintain proper function.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eOne\u003cspan\u003e \u003c\/span\u003e\u003cem\u003ein vivo\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003estudy performed on rats’ response to quercetin administration over the course of 7 days looked at changes in mitochondrial biogenesis (formation of new mitochondria) in skeletal muscle and brain, and on endurance exercise tolerance. The markers accessed were mRNA expression of PGC-1alpha, and SIRT1, mtDNA, and cytochrome c concentration. Quercetin administration showed increases in all of these markers as well as were associated with an increase in both maximal endurance capacity and voluntary wheel-running activity. These benefits, along with more promising studies being conducted, show how effective quercetin supplementation can be in improving mitochondrial function and enhancing the human bodies overall performance. In addition to these performance benefits, mitochondrial biogenesis stimulation can play an important role as an adaptive mechanism in the response cells have to different stressors as well as provide a protective mechanism against a broad range of acute and chronic diseases that are often manifested by mitochondrial dysfunction.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBIONMN® (Beta-Nicotinamide Mononucleotide)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNicotinamide Mononucleotide (NMN), is a ribo-nucleotide, which is a simple structural unit of RNA. NMN is the direct precursor of nicotinamide adenine dinucleotide (NAD+) and is considered a vital component to cellular increases in NAD+ levels. What is NAD+? NAD+ is an essential coenzyme that is required to produce ATP (adenosine triphosphate), or the fuel that is used by almost all of our body’s cells for functions. As we age, NAD+ levels naturally decline, which in turn can lead to less-than-optimal functioning and ultimately the onset of disorders like obesity, insulin resistance, and impaired cognitive function. While humans cannot absorb NAD directly, use of NAD+ precursors, like NMN, can prove to be beneficial for maintaining levels of NAD+. BioNMN®, from NNB Nutrition, emphasizes enhanced bioavailability so that the full benefit of this ingredient is able to be achieved.\u003c\/p\u003e\n\u003cp\u003eNMN supplementation has a wide range of benefits that has an influence on nearly all body system functions, from brain and cardiovascular improvements, suppression of age-related adipose tissue inflammation, neuroprotection, hormonal health, mitochondrial function, enhancing muscle endurance and strength, and longevity. Focusing on these benefits, all of these body systems need a coenzyme to facilitate the cascading effects leading to their benefits. In the context of improving muscle endurance and strength, our skeletal muscles require significant amounts of vital energy molecules in order to maintain their functionality, stability and strength. NAD+ is required in order to metabolize these molecules, thus our muscles can greatly benefit from a steady supply of its building blocks, such as NMN.\u003c\/p\u003e\n\u003cp\u003eAs mentioned before, mitochondria are essential cellular structures that act as the powerhouse of each cell. These organelles even have their own DNA. Mitochondria are critical for metabolism, meaning they work to convert molecules from food we consume into energy our bodies can utilize for function. NAD+ is at the root of this metabolism, meaning that without NAD+, mitochondria cannot metabolize thus leaving our cells without energy, and ultimately dying as a result. Studies have shown that through NMN supplementation, its role in increasing NAD+ production can protect mitochondria from dysfunction as well as maintain proper mitochondrial functioning by ensuring that metabolism is able to take place.\u003c\/p\u003e\n\u003cp\u003eWhere NMN rises to enhance longevity is that a lot of these bodily functions decrease with age. By ensuring that NAD+ levels are able to be maintained or supported through this aging process the hypothesized goal is to mitigate the normal aging process as much as possible to allow for optimal functioning of all body systems for a long period of time, whereas without optimal levels the risk of dysfunction and disease rises significantly.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePro-GBB™ (Gamma Butyrobetaine Ethyl Ester HCL)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCore LifeLine’s LONGEVITY uses the trademarked form of Gamma Butyrobetaine Ethyl Ester HCL, or GBB for short, Pro-GBB™. GBB is a naturally occurring molecule in the body that aids in the boosting of the non-essential amino acid L-carnitine. L-carnitine plays a key role in energy production by its ability to transport fatty acids into the cell’s mitochondria (‘energy producing powerhouse’) to be used for energy. Studies have shown that when GBB is present it can increase the bodies L-carnitine supply, thus providing enhanced benefits. So, in simplified terms, GBB increases usable L-carnitine in the body which increases the mitochondria’s ability to use fatty acids for energy. With the goal of reducing body fat or even improving performance, L-carnitine shows particular benefits in this field. A study conducted on mammals looked at the responses of L-carnitine supplementation on growth performance as well as circumference measurements. The results showed that weights of muscle tissue increased, whereas abdominal fat percentage decreased.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAstraGin®\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e(Astragalus membranaceous and Panax notoginseng)\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eRoot Extracts\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAstraGin® is a trademarked combination of Astragalus membranaceous and Panax notoginseng that has been widely used in the supplement manufacturing industry largely for due to its clinically studied benefits for improving absorption of nutrients, peptides, and amino acids. Some statistics include increased absorption of creatine, leucine, citrulline, and other peptides by up to 67%, increased curcumin absorption by 92%, increases polyunsaturated fatty acids (from flax and fish oil) by 58% and 100% respectively, as well as can increase ATP production in the liver by 18%. AstraGin® has been shown capable of increasing muscle protein synthesis and increased mTOR through enhanced leucine absorption, which has an influence on improved glucose metabolism and mitochondrial functions. In addition to this benefit, AstraGin’s® ability to enhance polyunsaturated fatty acid absorption while also inhibiting saturated fatty acid absorption, thus reducing the risk of impaired glucose metabolism and mitochondrial function, can enhance ATP synthesis through mitochondrial respiration, and increase oxidative phosphorylation.\u003c\/p\u003e\n\u003cp\u003eIt has been further studied how Astragalus and Panax notoginseng specifically can protect mitochondria and enhance their function towards anti-aging. The proposed mechanism leads to Astragalus acting as a free radical scavenger, which has the ability to inhibit mitochondrial permeability transition and increase the activity of antioxidants against the peroxidation of membrane lipids. Panax notoginseng also works in a similar fashion through decreased free radical production. This lipid peroxidation has been shown to be a major cause of decreases mitochondrial function. In addition to this, ensuring a highly permeable environment around the mitochondrial membrane is crucial for maintaining mitochondrial functions. This permeability allows for the passage of key electro chemicals to cross the gradient allowing for the process of energy development for the cells. These are just a few of the studied benefits that Astragalus and Panax notoginseng have on mitochondrial function but it paints a clear picture as to how they can influence energy metabolism and work to enhance protect mitochondrial functions, improve anti-aging activity, and enhance longevity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePyrroloquinoline Quinone (PQQ)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWe know that having more mitochondria present and their health has an impact on overall health, energy levels, inflammation levels, oxidative stress, etc. Dysfunction of these mitochondria can play a role in numerous chronic diseases and other metabolic disorders. Pyrroloquinoline Quinone, also known as PQQ, is a powerful redox cofactor that can act as both a prooxidant and antioxidant that protects cells in the human body from oxidative damage by restoring redox balance. It also has been shown to support the metabolism of energy and healthy aging. Deficiency of PQQ has also been shown in animal studies to lead to reduction in number and size of mitochondria by upwards of 20%-20%. PQQ supplementation can increase mitochondrial biogenesis through a mechanism of action by activating proliferator-activated receptor-gamma-coactivator-1 alpha (PGC-1α) and 3',5'-cyclic adenosine monophosphate response element-binding protein (CREB). Studies conducted on animals have shown that PQQ supplementation stimulates this PGC-1α-mediated mitochondrial biogenesis through sirtuin 1 activity and may also activate 5’-adenosine monophosphate-activated protein kinase (AMPK), which is another important regulator of mitochondrial biogenesis. While most studies on PQQ have been conducted on animals, human studies are showing promise as well. One randomized controlled trial conducted on men while also engaging in an endurance exercise program showed that while the two groups didn’t exhibit much of a difference in performance metrics, there was a significant increase in PGC-1α protein levels. This most likely relates to an increase in number of mitochondria present in the supplemented group. While exercise can indeed multiply mitochondria through biogenesis, PQQ supplementation can potentially work through mechanisms that build new mitochondria as well. When exercise becomes less frequent, and our ability to stimulate new mitochondria on our own stops, PQQ supplementation can be an essential tool for increasing longevity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePuremidine® (Spermidine Trihydrochloride)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIt might be common knowledge but it is important to remember that efficient cellular functioning is essential to our overall health, wellness, and longevity. We often only discuss large variables, like training, macronutrients, sleep, etc. as being essential (which they are) that we tend to forget the importance of how our cellular building blocks and our internal playing field influence our overall well being and health and wellness goals. Improving bodily function at the cellular level first can prove more fruitful in some aspects as it involves addressing certain problems at the source or providing support where most issues usually begin.\u003c\/p\u003e\n\u003cp\u003eCells are involved in all of our bodies processes and functions. From metabolism, respiration, muscle growth, and organ function, our body is essentially controlled by cells and their actions. Now just like our daily obligations require us to be attentive, fit, and ready to take on tasks so does our body rely on these cells to physically capable of performing under the rigors that we put our bodies through. Our body utilizes several processes to ensure our cells are able to perform to their required capabilities. Apoptosis, or programmed cell death; necrosis, or premature death; and autophagy, or disposing of defunct cells (recycling). Spermidine, a polyamine, is thought to enhance this process of autophagy. This recycling of defunct cells allows them to then be used elsewhere in the body to maintain health. This defense mechanism has been shown to support the regression of metabolic disorders, neurodegenerative disorders, and signs of aging. This process does slow with age, so utilizing tools that can help maintain this recycling process can be essential at prolonging longevity. Spermidine can in fact be found in foods we consume. Mushrooms, broccoli, organ meats, apples, etc. are just a few but supplementation can also prove essential at keeping our spermidine levels elevated as we age and if these foods are not eaten in sufficient quantities on a day-to-day basis. Although clinical data on spermidine at this moment has been limited to in vitro tests or in mice, these tests do give some evidence to improved health variables related to aging in humans due to its impact at the cellular level on vital cell structures like mitochondria.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":43573667594482,"sku":"corelongevity","price":54.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/corelongevity.jpg?v=1661847879"},{"product_id":"core-mrp","title":"Core MRP","description":"\u003ch2 style=\"text-align: center;\"\u003eCore MRP (\u003cb data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eFull Spectrum Meal Replacement)\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h2\u003e\n\u003cp\u003eCore MRP is designed with optimal results in mind. This high quality, grain-sourced carbohydrates, multiple (and rich) protein sources, premium flavors, and a plethora of extras all come in a gourmet-tasting, instantized powder.\u003c\/p\u003e\n\u003ch3\u003eCore MRP Highlights\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtein blend\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- \u003cspan data-mce-fragment=\"1\"\u003eSustained release for all day amino acid support \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarb blend\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- Low glycemic and grain-sourced carbohydrates\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicronutrients\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e- Full spectrum of vitamins and minerals\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Core Nutritionals","offers":[{"title":"3 LBS \/ Death by Chocolate","offer_id":48782385021170,"sku":"coremrprotein-dbc","price":49.99,"currency_code":"USD","in_stock":false},{"title":"3 LBS \/ Vanilla Poundcake","offer_id":47538144968946,"sku":"coremrprotein-vpc","price":49.99,"currency_code":"USD","in_stock":true},{"title":"3 LBS \/ Cookies n' Cream","offer_id":48782385086706,"sku":"coremrprotein-cnc","price":49.99,"currency_code":"USD","in_stock":true},{"title":"3 LBS \/ Caramel Chocolate Bar","offer_id":43573735358706,"sku":"coremrprotein-carchocbar","price":49.99,"currency_code":"USD","in_stock":false},{"title":"3 LBS \/ Smores","offer_id":43573735391474,"sku":"coremrprotein-smores","price":49.99,"currency_code":"USD","in_stock":false},{"title":"3 LBS \/ Carrot Cake","offer_id":43573735424242,"sku":"coremrprotein-carcke","price":49.99,"currency_code":"USD","in_stock":false},{"title":"3 LBS \/ Blueberry Crumble","offer_id":43573735457010,"sku":"coremrprotein-blucrum","price":49.99,"currency_code":"USD","in_stock":false},{"title":"3 LBS \/ Brown Sugar","offer_id":44536049959154,"sku":"coremrprotein-brownsugar","price":49.99,"currency_code":"USD","in_stock":false},{"title":"3 LBS \/ Banana Nut Bread","offer_id":47538144608498,"sku":"coremrprotein-bnb","price":49.99,"currency_code":"USD","in_stock":false},{"title":"3 LBS \/ Double Chocolate Oatmeal Cookie","offer_id":47538144674034,"sku":"coremrprotein-dcoc","price":49.99,"currency_code":"USD","in_stock":true},{"title":"3 LBS \/ Peanut Butter Oatmeal Cookie","offer_id":47538144805106,"sku":"coremrprotein-pboc","price":49.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/MRP_DC_FRONTLarge.jpg?v=1771802335"},{"product_id":"core-omega","title":"Core Omega","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Omega\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCore OMEGA contains high levels of the all-important DHA and EPA, with 480mg and 720mg respectively in each serving. Produced under a nitrogen barrier, this is the purest fish oil product possible.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePhysiological properties and effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNitrogen Barrier Production\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOil derived from marine animals – commonly referred to as “fish oils” – are widely consumed for the high amounts of polyunsaturated fatty acids (such as DHA and EPA) that they contain and the potential health benefits that these fatty acids confer. Unfortunately, polyunsaturated fatty acids are notoriously unstable: they are composed of double-bonds between carbon atoms, a chemical structure that is notoriously susceptible to oxidation. (Oxidation is the process of producing oxygen species as a consequence of a compound’s exposure to oxygen.)\u003c\/p\u003e\n\u003cp\u003eFor fish oil, oxidation has a number of deleterious effects – principally, the production of hydroperoxides (the first step in oxidation) and secondary oxygen products not only produce the rancid, “fish” smell typically associated with lower quality fish oil products; but perhaps more importantly, in breaking the double bond structure of the fish oil, these oxygen species degrade the integrity of the product and thus reduce their potential health benefits. The oxidation degradation is unfortunately widespread. One study found that 50% of 171 fish oil supplements in Canada exceeded the limits for at least one measure of oxidation, and 39% exceeded the international voluntary safety recommendations for total oxidation (TOTOX value).” Another study found that approximately 29% of fish oil supplements in the United States similarly exceeded recommended values.\u003c\/p\u003e\n\u003cp\u003eLuckily, research has shown that reducing the exposure of fish oils to oxygen and environmental factors (humidity and temperature fluctuations) during the production process can significantly mitigate oxidation. One of the most effective ways to reduce oxygen exposure is to blanket the oil, as soon as its processed and produced, in an inert gas such as argon or nitrogen – thereby preventing the fish oil from coming into contact with oxygen at all. While exact values will vary by product, research has shown that both primary oxidation (the production of hydroperoxides, measured in peroxide value, PV) and secondary oxidation (measured in TOTOX (total oxidation value) and a-nsidine values) are vastly reduced through a nitrogen blanket or barrier. \u003c\/p\u003e\n\u003cp\u003eIn sum, producing fish oils under a nitrogen blanket or barrier not only reduces the rancid smell typically associated with fish oil products; but vastly extends their shelf life and integrity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cbr\u003eTriglycerides vs Ethyl Ester Forms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWe have established that\u003cspan\u003e \u003c\/span\u003e\u003cem\u003ehow\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003efish oils are produced may impact their viability as a dietary supplement. But the production process is not the only salient factor in fish oil efficacy and viability – the\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eform\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003ethat a fish oil takes is paramount, as well. Specifically, the differences between triglycerides and ethyl esters may be formative in how fish oils are absorbed and confer their potential health benefits.\u003c\/p\u003e\n\u003cp\u003eFirst, a little primer on what triglycerides and ethyl esters are. Triglycerides are a molecular form common to almost all plant and animal species: a glycerol backbone with three fatty acids (in the case of fish oils, EPA and DHA) attached to them. For example, the “stuff” of human adipose (fat) tissue is triglycerides. Ethyl Esters, on the other hand, lack a glycerol backbone – they are a single fatty acid molecule attached to an ethanol molecule. Unlike triglycerides, ethyl esters are not a natural molecular form and formed solely through chemical synthesis.\u003c\/p\u003e\n\u003cp\u003eWhile the difference between triglycerides and ethyl esters as applied to fish oil may seem academic, it in fact has profound implications for the absorption and bioavailability of these oils. In very condensed form, the issue is twofold: how the fish oil is taken up into the bloodstream (absorption) and how it is made available to cells once that has occurred (bioavailability). In both contexts, there is evidence that triglycerides are superior to the ethyl ester form.\u003c\/p\u003e\n\u003cp\u003eFor bioavailability, the issue is how the small intestine breaks down each form of fish oil. As a natural product, our bodies are intrinsically capable of breaking down triglycerides via bile salts and pancreatic lipase. Once ingested, pancreatic lipase and bile salts are released, and in the small intestine, the triglyceride is broken down into so-called emulsion droplets – which can then easily be broken up, detaching the two fatty acid molecules from the glycerol backbone. Not so with ethyl esters. Not only is pancreatic lipase (by some estimates) 50% less effective in breaking down ethyl esters; but once digested, ethyl esters must be\u003cspan\u003e \u003c\/span\u003e\u003cem\u003econverted\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003einto triglycerides through the liberated fatty acids attaching to a glycerol molecule. Essentially, your body must reverse the entire metabolism of ethyl esters, then go through the normal triglyceride metabolism.\u003c\/p\u003e\n\u003cp\u003eThe biochemical differences between triglycerides and ethyl esters have been demonstrated in trials examining bioavailability and absorption efficiency. One study found that, when ingested in triglyceride form, EPA and DHA levels were 340% and 271%, respectively, as compared to the ethyl ester form. Additional research has found a 25% increase in plasma EPA and DHA levels over a six month period; that ethyl esters are “poorly absorbed” by man; and that triglyceride form fish oils suffer less oxidation (on shelf) than the ethyl ester form.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEPA and DHA\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNow that we know why producing fish oils under nitrogen barrier protects the integrity of fish oil, and why triglycerides are superior to ethyl esters, we have only one major question left:\u003cspan\u003e \u003c\/span\u003e\u003cem\u003ewhat benefits do fish oils (specifically, EPA and DHA) pose to humans\u003c\/em\u003e?\u003c\/p\u003e\n\u003cp\u003eEicosapentaenoic acid (EPA) and cocosahexaenoic acid (DHA) have myriad health benefits, but their best-studied (and approved by the FDA) use is to balance and maintain healthy triglyceride levels. Triglycerides, as we mentioned, are produced naturally by most animals. They are necessary for a wide range of physiological function, but their overabundance is implicated in a number of pathological conditions. As a consequence, ingesting external forms of triglycerides – such as fish oils – can help balance triglycerides and maintain healthy levels. In perhaps the most robust meta-analysis to date, researchers examined 11 randomized human trials, comprised of 485 total individuals with a mean age of 25 to 49. The meta-analysis found robust evidence that DHA, specifically, exerts a significant triglyceride lowering and balancing effect. A similar meta-analysis focused on EPA found that its effects were comparable to DHA.\u003c\/p\u003e\n\u003cp\u003eBoth of these polyunsaturated fatty acids are best known for their triglyceride-lowering function, each exerts other interesting effects as well. Significant evidence suggests that EPA and DHA may mitigate the production of pro-inflammatory cytokines, molecules responsible for inducing the inflammation cascade in the body. Others studies suggest high levels of brain DHA are associated with verbal fluency and memory in healthy, normal adults – with one study finding that 6 months of DHA supplementation in young, healthy adults increased working memory assessed by recall.\u003c\/p\u003e\n\u003cp\u003eOne of fish oil’s (specifically, EPA’s) effects that may be of interest to fitness and physique athletes is its ability to induce AMPk (adenonsine monophosphoate kinase). AMPk, otherwise known as the “master metabolic switch,” is a heterotrimeric enzyme responsible for energy catabolism in muscle and fat cells. When activated, AMPk increases lipolytic (the catabolism of fat tissue) signaling as a means of energy provision. Several studies demonstrate that high levels of EPA indirectly stimulate AMPk activation via decreasing PPARy.\u003c\/p\u003e\n\u003cp\u003eThough less well-studied or confirmed, emerging research suggests that DHA and EPA levels may be formative in maintaining healthy and normal moods, due to altering certain neurological proteins. These literature require follow-up and replication, but show promise in establishing a new purpose for DHA and EPA supplementation.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":43573755478258,"sku":"coreomega","price":41.49,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/omegacore.jpg?v=1661849205"},{"product_id":"core-multi","title":"Core Multi","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Multi\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCore Multi not only with 100% (and often more) of almost all your essential vitamins and minerals, but also a broad-spectrum antioxidant blend antioxidant blend (Spectra™), berberine HCL, and numerous trademarked forms of vitamins and minerals. If you need a broad range of essential vitamins and minerals in sufficient amounts and in the most efficient forms, then Core MULTI is for you.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eB Vitamins (Thiamine, Riboflavin, Niacin, B6 [Pyridoxine], Folic Acid, B12, Biotin, and Pantothenic acid)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eB vitamins are a group of eight essential vitamins with several critical functions in the body. Though both molecularly and physiologically distinct, they are also deeply interrelated in their effects, synthesis and metabolism. Among the B-complex’s many critical roles are energy (protein, carbohydrates, and fat) metabolism, supporting and maintaining the healthy function of the adrenal glands, skeletal muscle function, and digestion.\u003c\/p\u003e\n\u003cp\u003eWhile rates of metabolism and clearance differ between each B vitamin, all B vitamins are water-soluble and are thus not stored in fat. As a result, the body simply excretes excess B vitamins in the urine and requires replenishment (from food or supplements) in order to maintain the cell functions to which B vitamins contribute.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin A (as Beta Carotene)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBeta carotene is itself not an essential vitamin but is rather the precursor to the fat-soluble and essential vitamin, vitamin A (Retinol). Like B vitamins, the term vitamin A refers to the compound class retinoids, comprised of retinol, retinal (also called retinaldehyde), retinoic acid, and provitamin A compounds such as beta carotene.\u003c\/p\u003e\n\u003cp\u003eAs their names suggest, retinoids are critical to the function of human eyes and therefore to the maintenance of circadian rhythms (our “biological clock”). Vitamin A combines with proteins in the eye to form light-sensing cells that both facilitate vision and regulate our sleep-wake cycles.\u003c\/p\u003e\n\u003cp\u003eBeyond its role in sight, vitamin A is also essential for cellular growth and differentiation and the immune system.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin C (as Ascorbic Acid)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin C is perhaps historically best-known for the treatment and prevention of scurvy, though it has many other roles in the body. For example, vitamin C catalyzes or is a cofactor in eight enzymatic reactions involved in the synthesis of collagen, the nutrient carnitine, and several neurotransmitters necessary for the proper function of the brain.\u003c\/p\u003e\n\u003cp\u003eIn the contemporary context, vitamin C is best known as a potent antioxidant. In addition to its intrinsic activity as an antioxidant, vitamin C has been shown in in vitro trials to regenerate alpha-tocopherol (vitamin E). As an antioxidant, vitamin C combats the detrimental effects of a group of compounds called radical oxygen species that, when produced, degrade the lipid membrane of the cell and may cause internal damage. By “scavenging” these free radicals, vitamin C and other antioxidants form a defense against excess cellular damage.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin D3 (as Cholecalciferol)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin D, in its various forms, is not an essential nutrient – as it is produced endogenously within the body, as a reaction to the skin’s exposure to the sun – and thus not commonly considered a vitamin. Despite its technical classification, vitamin D (a hormone), is nevertheless an import and biologically-active compound, necessary for the calcium homeostasis and metabolism, along with increasing the absorption of magnesium and phosphate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin E (as Mixed Tocopherols)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin E is another technical misnomer, as the term refers to a group of compounds known as tocopherols with eight biologically-active constituents: alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol. Alpha-tocopherol is the principal bioactive in humans, though the presence of other tocopherols has been linked to beneficial effects.  \u003c\/p\u003e\n\u003cp\u003eAs a result of its robust antioxidant activity, vitamin E assists in the maintenance and support of several physiological processes, though most notably sight and the immune system. Emerging research also suggests that the alpha-tocopherol form of vitamin E inhibits an enzyme known as protein kinase C, and therefore contributes to the healthy regulation of smooth muscle cell growth and differentiation.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eCritically, we have used the natural version of vitamin E (technically d-alpha tocopherol) and not the synthetic (dl-alpha tocopherol). The difference is a meaningful one: the single isomer of d-alpha tocopher\u003c\/span\u003e\u003cspan\u003eol is easier and more efficiently absorbed and used in the body as compared to the eight isomers in the dl analog.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCalcium (as Calcium Carbonate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhile best-known as the main bioactive in milk, and a compound that contributes to strong bones, calcium has numerous physiological effects in the body – including mediating vascular contraction and vasodilatation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion. Homeostatic regulation of calcium, which the body cannot produce, requires sufficient levels of vitamin D.\u003c\/p\u003e\n\u003cp\u003eWhen present in sufficient amounts, calcium is necessary for the adequate formation, function, and remodeling of both bone and teeth. Insufficient levels of calcium are associated with degenerative bone and joint disorders such as osteoporosis, wherein bone accretion slows or stops; thereby reducing bone mass and density and decreasing bone strength.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIodine (As Kelp (Ascophyllum nodosum))\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIodine is a trace element naturally present in certain foods, including kelp. Iodine is a critical component for fetal development, especially during early pregnancy, as maternal T4 (thyroxine) is the sole source of fetal thyroid hormone. After birth, especially if breast-feeding, iodine remains an important constituent of a balanced-diet to maintain adequate T3 (triiodothyronine) and T4 (thyroxine) levels in the mother and for the proper cognitive development in the child.\u003c\/p\u003e\n\u003cp\u003eAs implied, however, the most important of iodine’s functions is assisting the body to produce and maintain healthy levels of both thyroid hormones and TSH (thyroid stimulating hormone, released by the pituitary). The thyroid hormones, in turn, regulate several critical biochemical reactions, including protein synthesis, and, along with norepinephrine\/epinephrine, largely determine the body’s metabolic rate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMagnesium (as Albion® Di-Magnesium Malate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIt is difficult to overstate the biological necessity of magnesium. Magnesium is a co-factor in over 300 enzymatic reactions that regulate essential physiological functions such as protein synthesis, glucose homeostasis, muscle and nerve function, and the maintenance and support of healthy blood pressure levels.\u003c\/p\u003e\n\u003cp\u003eMagnesium is also required for the use of the body’s energy currency, ATP. To become biologically active, ATP must be bound to magnesium to form Mg-ATP. In addition, magnesium is necessary for the proper function of cells with calcium and potassium gated ion channels such as heart and muscle cells.\u003c\/p\u003e\n\u003cp\u003eIn men, magnesium (along with zinc) is necessary for the maintenance of healthy levels of testosterone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eZinc (as Zinc Aspartate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs an essential mineral, like magnesium, zinc is also involved in a wide-range of essential biological functions in the human body – and a requirement in the catalytic activity of over 100 enzymes.\u003c\/p\u003e\n\u003cp\u003eMost notably, zinc is vital for immune function, protein synthesis, cellular division, and DNA synthesis. For immune function, zinc is required for the function of a group of immune cells known as neutrophils and macrophages, which eliminate pathological cells and their products from the body.\u003c\/p\u003e\n\u003cp\u003eWith magnesium, sufficient levels of zinc are also necessary for the production and maintenance of healthy levels of testosterone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCopper (as TRAACS® Copper Bisglycinate Chelate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCopper is a trace element necessary for the production, function, and maintenance of a diverse range of compounds involved in physiological function.\u003c\/p\u003e\n\u003cp\u003eThe brain, the heart, bone, and connective tissue specifically require copper or the enzymes it catalyzes to properly grow and differentiate their various cell types. Like many of the ingredients in Core MULTI, copper is also required for the homeostasis of other minerals, specifically zinc.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eManganese (Manganese Citrate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eManganese is a required element for not only humans, but all living organisms. Manganese primarily acts as an antioxidant, specifically scavenging a radical oxygen species known as superoxide.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChromium (as Chromium Picolinate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eChromium is an essential, though little understood, trace element found in certain foods and industrial compounds. Only one of chromium’s two forms, the form used in Core MULTI, chromium 3+, is biologically active.\u003c\/p\u003e\n\u003cp\u003eWhile not as well-defined as other trace elements, chromium’s physiological actions nevertheless seem pivotal to the production and transmission of healthy levels of insulin. Emerging research also seems to suggest that chromium is directly involved in the metabolism of carbohydrates.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMolybdenum (as TRAACS® Molybdenum Glycinate Chelate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMolybdenum is an essential trace element, involved in at least four enzymatic reactions necessary for urea excretion and a number of other physiological functions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBerberine HCL\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThere is extensive literature demonstrating that berberine is a potent AMPk agonist in skeletal muscle. Based on the pharmacological similarities between berberine and the anti-diabetic medicine metformin (with respect to AMPk activation), it is possible that berberine may promote an anti-catabolic state through increased expression of AMPk. \u003c\/p\u003e\n\u003cp\u003eThe human data – in both healthy and disease state populations – demonstrating berberine’s other physiological effects are numerous. A 2012 meta-analysis examined 14 randomized trials, containing 1068 patients, and assessed berberine’s efficacy in numerous biometrics, including resting plasma glucose levels, plasma insulin levels, body weight, body mass index, and reduction in fat mass and serum triglycerides and total cholesterol content. The aggregate data suggests that berberine performs at least as well as oral hypoglycemic agents (such as metformin) in these key metrics.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBoron Citrate\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBoron is a mineral present in multiple fruits, vegetables, tubers, and drinking water, though it is not widely accepted as either an essential mineral or essential vitamin. Boron affects a few physiological functions in the body, particularly modulating hormonal homeostasis.\u003c\/p\u003e\n\u003cp\u003eWhile still emerging, recent data suggest that boron may play a role in potentiating free testosterone levels in even healthy men. In one study, otherwise healthy men were provided an acute serving of boron and had their free and total levels of testosterone, alone with SHBG (sex hormone binding globulin) and DHT (dihydrotestosterone) levels measured. In that study, total testosterone was unaltered, but free testosterone was enhanced by 14%, while SHBG was significantly (9%) reduced.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCholine (as Choline Bitartrate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e Choline is an essential nutrient involved in numerous metabolic pathways, including DNA regulation and repair, protein function, and metabolism. Perhaps most importantly, the critical neurotransmitter acetylcholine is produced directly from free choline via cholinergic neurons. Acetylcholine is then responsible for a number of functions itself, most crucially as the compound which induces muscular contraction, and as the neuromodulator partially responsible for modulating risk\/reward, arousal, and enhancing memory.\u003c\/p\u003e\n\u003cp\u003eCholine’s essential role as a substrate for acetylcholine, and therefore brain development, is well documented in animal models. These studies demonstrate that levels of free maternal choline have a direct and fundamental impact on prenatal brain development, with the enhancements or deficits lasting into adulthood. Choline’s enhancing effect is particularly prominent in the hippocampus. In humans, the hippocampus is primarily involved in the consolidation of memory (taking short, episodic memory and translating it into long-term memory) and the learning of new information. Acetylcholine is a critical component in these processes, as mentioned above, and choline may therefore play a potential role in these processes as well by providing the substrate for acetylcholine synthesis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSpectra™\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSpectra™ is the first scientifically validated formula of fruits, vegetables, and herbs shown to inhibit free radical production, optimize cellular metabolic activity, and increase nitric oxide levels within our bodies\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":43573767700722,"sku":"coremulti","price":33.49,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/coremulti.jpg?v=1661849424"},{"product_id":"core-test","title":"Core Test","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Test\u003c\/h2\u003e\n\u003cp\u003eBeing at your best, your peak, isn’t a subjective state of mind or a feeling one has – it’s a physiological state, a confluence of metabolic factors that result in the best, most peak, most alpha version of you stepping out into the world and into the gym every day. Are you doing what’s necessary to be there?\u003c\/p\u003e\n\u003cp\u003eIf not, then Core has your back with the newest evolution in healthy testosterone and male support: Core TEST. By now, you already know the drill: we take the best ingredients, backed by clinical research, and include them in serving sizes actually reflected in the literature. Core TEST is no different.\u003c\/p\u003e\n\u003cp\u003eWe’ve scoured the literature, alpha and beta tested more formulas than you can count, and eventually created a formula packed with actually effective ingredients targeting multiple pathways of healthy testosterone support. Calcium DAA, one of the best known support supplements on the market, backed by clinical research in humans. KSM66, an ingredient with a long history of use in traditional medicine now backed by an unimpeachable record of cortisol reduction, healthy testosterone support, and hormone optimization. We could’ve given you KSM66 and left it at that – the ingredient is that good. But we didn’t. We included Bulbine natalensis, Tongkat Ali, and a potent estrogen modulator in Pine extract to cap off the savagery. This is the best, most comprehensive, multi-pathway testostone support product on the market.\u003c\/p\u003e\n\u003cp\u003eAll in all, we have created a formula that you’ll know is working. If you don’t know your best yet, you’ll certainly know it when Core TEST helps you reach it.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"28 Servings \/ Black Lightening","offer_id":43573787853042,"sku":"coretestbooster-1","price":63.49,"currency_code":"USD","in_stock":false},{"title":"28 Servings \/ Primal Punch","offer_id":43573787885810,"sku":"coretestbooster-2","price":63.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/coretestblack.jpg?v=1661849735"},{"product_id":"core-shred","title":"Core Shred","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Shred\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eWhether you’re taking a break from stimulants, are stimulant sensitive, or simply want a non-stimulant thermogenic to stack with our excellent stimulant-based offerings, Core SHRED is the perfect solution. Use it anytime, night or day, to help crush your regular exercise program and consistent diet!\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/nonstimfatburner_480x480.jpg?v=1667109303\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcetyl-l-Carnitine:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eL-carnitine is a derivative of the amino acid lysine and, as certain conditions outpace the body’s ability to produce it, l-carnitine is considered a conditionally essential amino acid. While endogenous biosynthesis of l-carnitine from the amino acids lysine and methionine is sufficient for essential processes – along with dietary sources of carnitine from protein-rich red meat, for example – dietary supplementation of carnitine may pose benefits in certain physiological conditions. Unfortunately, due to excess metabolism of l-carnitine by microorganisms in the small intestine, exogenous supplementation with oral l-carnitine has proved ineffective. ALCAR, an acetylated version of l-carnitine, has considerably higher oral bioavailability, due likely to only partial hydrolytic metabolism. Once in the bloodstream, ALCAR plays a fundamental role in the production of energy, acting as the catalyst for the beta-oxidation of long chain fatty acids by the mitochondria; regulating the CoA to Acyl-CoA ratio (necessary for the production of ATP); and the metabolism of carbohydrates. ALCAR also is an excitatory agent for neurons, increases neuronal transmission, and increases the production of neurotransmitters and neurohormones such as dopamine and serotonin.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOlive Extract (Oleaeuropaeai) (leaf) (20% oleuropein):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eOlea europaea\u003c\/em\u003e, more commonly known as the olive, is a species of a small tree in the family Oleaceae, native to the coastal areas of southeastern Europe, western Asia and northern Africa, as well as northern Iran at the south end of the Caspian Sea. As the fruits, oils, and extracts of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eOlea europaea L\u003c\/em\u003e. are a dietary component for a significant portion of the world’s population, the plant has become associated with a wide-range of physiologic and metabolic benefits. These properties are largely attributed to the phenolic compounds of olive leaves, including: caffeic acid, verbascoside, oleuropein, luteolin 7-O-glucoside, rutin, apigenin 7-Oglucoside, and luteolin 4′-O-glucoside. Collectively, these olive polyphenols are responsible for a wide-range of postulated health benefits.\u003c\/p\u003e\n\u003cp\u003eOleuropein, in particular, is purported to have several pharmacological properties including antioxidant, anti-inflammatory, anti-atherogenic, and anti-microbial effects. Recent research inanimals has also demonstrated that oleuropein may potentiate the response of 5'-deiodinase, the enzyme responsible for the irreversible conversion of thyroxine (T4) into triiodothyronine (T3), the active thyroid hormone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eColeus forskohlii root extract (20% forskolin):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eColeus forskohlii\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis a small perennial endemic to various tropical regions in the world, including South America, sub-Saharan Africa, and India. While the West has recently taken interest in the plant due to the pharmacological properties of its primary bioactive, forskolin, Coleus forskholii preparations and tinctures have been used in both South American and African traditional folk medicinal systems, as well as extensively within Ayurveda. Due to the ever-increasing interest in the plant’s verifiable pharmacological and physiological effects, however, Coleus forksholii and its extracted constituents have been the subject of numerous animal and human clinical trials in the past decade. These trials have demonstrated the plant to have various effects and applications, including as a lipolytic and anti-lipogenic, and as a powerful antioxidant.\u003c\/p\u003e\n\u003cp\u003eA recent double-blind, randomized, and placebo-controlled human clinical trial featuring obese men found that the daily implementation of Coleus forskholii, for twelve weeks, led to significantly better weight loss outcomes as compared to controls. Overweight men in the forskolin group experienced not only improved body composition (as measured by both body fat percentage and total fat mass), but also statistically significant increases in lean body mass. Coleus forskholii – and more specifically, forskolin – achieves this effect by rapidly, potently, and dose-dependently increasing an important metabolic enzyme known as adenylate cyclase. Adenylate cyclase is an enzyme responsible for catalyzing the formation of cyclic adenosine monophosphate (cAMP) from adenosine triphosphate (ATP). This increase in cAMP formation eventually leads to the activation of an enzyme, protein kinase A, which in turn will phosphorylate and hence activate the enzyme, Hormone Sensitive Lipase (HSL) – the rate-limiting enzyme necessary for stored triglycerides within adipocytes to be released as free fatty acids and utilized for energy. In more basic terms, this means that forskolin quite literally frees up more fatty acids to be used as fuel for exercise – more or less the perfect scenario in a product such as Core SHRED!\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCapsiAtra®:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCapsiAtra® is a dihydrocapsiate compound naturally found in CH-19 Sweet peppers. Like several other capsinoids identified and extracted from pepper species, CapsiAtra® has demonstrated potent effects on several physiological pathways – most notably, those related to energy expenditure and lipid utilization.\u003c\/p\u003e\n\u003cp\u003eCapsiAtra® is a dihydrocapsiate compound naturally found in CH-19 Sweet peppers. Like several other capsinoids identified and extracted from pepper species, CapsiAtra® has demonstrated potent effects on several physiological pathways – most notably, those related to energy expenditure and lipid utilization.\u003c\/p\u003e\n\u003cp\u003eThe thermogenic and lipolytic effects of capsinoids, like capsaicin itself, are mediated by the Transient Receptor Potential Vanilloid 1 (TRPV1) receptors in the mouth and throughout the gastrointestinal tract. TRPV1 receptors in the gut are linked with the sympathetic nervous system (SNS). When activated, they increase SNS activity (the figure below). TRPV1 receptors present on the tongue and in the oral cavity are responsible for, among other things, detection of thermal heat. When capsaicin binds to oral TRPV1 sites, one feels the sensation of heat and pungency. Capsinoids also stimulate TRPV1 receptors, but their effect is primarily on receptors in the throat and gut, not the mouth. Owing to the structural differences from capsaicin, the capsinoids are unable to reach the TRPV1 receptors on the tongue, which are located slightly below the mucosal surface. As a result, capsinoids do not produce the oral sensation of heat or the pungent taste associated with chili peppers, but they do produce the capsaicin-like SNS response once they bind to TRPV1 receptors in the throat and gut.\u003c\/p\u003e\n\u003cp\u003eThe capsinoids have multiple biological functionalities. The sports nutrition properties are directly linked to their use in energy manipulation. The capsinoids have three principal mechanisms of action. First, they up-regulate UCP-3 (Mitcohondrial Uncoupling Protein-3) in muscle cells. This causes ATP production to be dissociated with the respiration occurring in the mitochondria. This energy is then released as heat: an effect that is mirrored in caloric restriction as a means to economize energy. Second, they up-regulate UCP-1 (Uncoupling Protein-1, aka Thermogenin). This protein is only expressed in brown adipose tissue and is used to generate non- shivering thermogenesis; a process that evolved to protect against hypothermia. The up-regulation of UCP-1 can positively affect fat utilization and improve insulin sensitivity of tissues. Third, the capsinoids stimulate lipolysis via hydrolysis of triglycerides into glycerol plus three fatty acids. The release of these free fatty acids into the circulation is key to the energy regulating properties of the compound. Allowing these to become readily available as energy sources during exercise means that oxidation of muscle glycogen can be delayed, resulting in significant improvements in endurance.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2440\/0931\/files\/core-sherd.png?v=1596464988\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGrains of Paradise Extract (12.5% 6-paradol)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eAframomum melegueta\u003c\/em\u003e, more commonly known as Grains of Paradise, or the alligator pepper, is a plant in the Ginger\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e(Zingiberaceae)\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003efamily. While complete compositional analysis have not been performed on Grains of Paradise, preliminary assays demonstrate is structural and chemical similarity to ginger – principally in that both ginger and grains of paradise contains a range of pungent bioactives, one of which is 6-paradol.\u003c\/p\u003e\n\u003cp\u003eAlong with 6-shogaol, 6-paradol appears to be the most bioactive of the approximately 14 pungent compounds identified in ginger. Both compounds appear to potently and dose-dependently mediate the PI3K (phosphoinositide 3-kinase)\/PKB (protein kinase B), leading specifically to an increase in AMPk phosphorylation. Known as the ‘master regulatory switch,’ AMPk is responsible for balancing endergonic (energy absorbing) and exogenic (energy liberating) processes in the body’s response to energy demands. AMPk is therefore heavily involved in adipocyte (fat cell) differentiation, proliferation, and hypertrophy, via regulating both enzymatic action (11B-HSD1, HSL, SREBP-1) and downstream lipogenic genes such as PPARy2.\u003c\/p\u003e\n\u003cp\u003eIn the case of gingerols such as 6-paradol, increased phosphorylation of AMPk in adipocytes appears to have a mitigating effect on hypertrophy by reducing lipid synthesis. 6-paradol appears to increase AMPk, which in turn decreases the mRNA expression of the downstream PPARy2 (peroxisome proliferate activated receptor gamma 2), a nuclear receptor gene principally responsible for lipid accumulation. In other words, the gingerols control a compound (AMPk) which, in turn, controls fat mass metabolism.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePro-GBB™ (Gamma Butyrobetaine Ethyl Ester HCL):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCore SHRED is using the trademarked form of Gamma Butyrobetaine Ethyl Ester HCL, or GBB for short, Pro-GBB™. GBB is a naturally occurring molecule in the body that aids in the boosting of the non-essential amino acid L-carnitine. L-carnitine plays a key role in energy production by its ability to transport fatty acids into the cell’s mitochondria (‘energy producing powerhouse’) to be used for energy. Studies have shown that when GBB is present it can increase the bodies L-carnitine supply, thus providing enhanced benefits. So, in simplified terms, GBB increases usable L-carnitine in the body which increases the mitochondria’s ability to use fatty acids for energy. With the goal of reducing body fat or even improving performance, L-carnitine shows particular benefits in this field. A study conducted on mammals looked at the responses of L-carnitine supplementation on growth performance as well as circumference measurements. The results showed that weights of muscle tissue increased, whereas abdominal fat percentage decreased.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"50 Servings \/ Tropical Heat","offer_id":43573802238194,"sku":"coreshred","price":44.99,"currency_code":"USD","in_stock":false},{"title":"50 Servings \/ Pineapple Strawberry","offer_id":44380542599410,"sku":"coreshred2","price":44.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/coreshred.jpg?v=1661890917"},{"product_id":"core-hair-skin-nails","title":"Core Hair Skin \u0026 Nails","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutritionals Hair, Skin and Nails\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eHAIR, SKIN and NAILS by Core Nutritionals addresses these often overlooked but important bodily components with a wide array of ingredients formulated to boost collagen synthesis, improve skin hydration, reduce wrinkles and fine lines, strengthen hair, reduce oxidative stress and support cellular and tissue health. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eCore Hair, Skin \u0026amp; Nails Highlights\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eMay Improve Skin, Nails \u0026amp; Hair Health \u0026amp; Looks\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eVery Effective Formula\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWell Dosed Ingredients\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eEffective Collagen \u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eCore Nutritionals Hair, Skin, \u0026amp; Nails Supp Facts\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin C (as Ascorbic Acid)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVitamin C is not only a powerful antioxidant, but also supports a healthy immune system, protects cells from oxidized particles and free radicals, and assists other physiological functions.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBiotin (as d-Biotin)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe main mechanism of action for biotin and its hair health promoting benefits comes from its proposed ability to help in preventing hair loss by rejuvenating both the hair follicles and scalp.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eMSM (Methylsulfonylmethane)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMSM is a naturally occurring, organosulfur molecule that can be synthesized both naturally and synthetically from DSMO. While the majority of MSM present in the human body is ingested – either deliberately or accidentally – the compound does have a natural presence in certain tissues and fluids in the body, including cerebrospinal fluid.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eHydrolyzed Keratin Peptides\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eConditioner is a common application most individuals include in their hair health regimen, but most people don’t know the real importance of incorporating protein specifically into the same regimen. This is where keratin comes into play, which as explained above is the main protein found in hair, skin, and nails. Hydrolyzed keratin has been shown to increase cysteine content, which increases tensile strength and minimizes damage. It also increases volume, strengthens your hair, and restores luster. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eAstrion™ (Astragalus membranaceus \u0026amp; Centella asiatica) Root Extracts\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eAstrion™ works through a process of triggering the body’s internal regeneration mechanisms to increase collagen and hyaluronic acid synthesis, as well as an increased absorption of proline (building block of collagen) and glucosamine (building block of hyaluronic acid) in skin cells. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eSetria® L-Glutathione\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eGlutathione is an amino acid containing molecule of L-glutamic acid, L-cysteine, and Glycine. It is vital to many different properties and is best known for being a powerful antioxidant. The ‘glutathione system’ comprises the enzymes that synthesize glutathione within a cell as dedicated enzymes that use glutathione for its antioxidant effects. Glutathione supplementation is thought to support this pool of glutathione present in cells and thus maintain the efficacy of the entire system. Free radicals can be a byproduct of many different things such as exercising, eating, and breathing to name a few.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eHyaluronic Acid (Sodium Hyaluronate)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSkin aging is as a result of several biologically independent processes. The first being an intrinsic, or unpreventable, process that affects the skin similar to how it affects our internal organs. The second is an extrinsic process, which is as a result of environmental factors such as ultraviolet (UV) exposure. While these intrinsic and extrinsic factors contribute to less than optimal looking and feeling skin, a loss of skin moisture is also a cause of this particular skin aging. The key molecule involved in maintenance of skin moisture is hyaluronic acid. Hyaluronic acid (HA), also known as hyaluronan, is a clear, gooey substance that is naturally produced by your body. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eDermaval® (Pomegranate Extract, Asparagus, Okra, CoffeeBerry® Extract, Quercetin, Acerola, Camu Camu, Acai, Mangosteen)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDermaval® is a blend of nine phytochemical-rich plant-based superfoods combined for their ability to coherently work to support the human body’s natural collagen levels as well as deliver nutrients to assist in natural collagen production. Pro-inflammatory enzymes, elastase and gelatinase, are known to wreak havoc on collagen and breakdown the vital tissue that is naturally produced by the body. Studies have shown that these pro-inflammatory enzymes may be stimulated by extrinsic factors (like UV light) or even our nutrition (food allergies\/sensitivities). \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCeramosides™ Wheat Extract\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e(Triticum sativum)\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003e(Seed) (std. to ≥ 50% glycosphingolipids, \u0026amp; ≥ 40% digalactosyldiacylglycerol (DGDG))\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCeramosides™ is a clinically studies sources of these ceramides, which are carried via the bloodstream to help restore the water barrier to provide adequate hydration as well as lubricating the skin providing a healthy glow. These lipids can also be vital for someone who experiences dry skin as a result of weather, which can result in painful cracks and weak skin layers. Acting as a moisturizer, these lipids can help fill these cracks and provide support for the skin to better withstand these factors.\u003c\/span\u003e\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":44380516810994,"sku":"hairskinnailscore","price":54.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/corenutritionalshair-skin-nails.jpg?v=1677365495"},{"product_id":"core-flex-joint-support","title":"Core Flex Joint Support","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutritionals Flex Joint Support\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eCore FLEX is an ultra-potent combination of 11 clinical ingredients, crafted to ensure the maintenance of strong and healthy tendons and ligaments. Best of all, its all-in-one blend combines the efficacy of single ingredient products, with the synergy of an entire joint product lineup.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan data-mce-fragment=\"1\"\u003eCore Flex Supp Facts\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eChondroitin and Glucosamine\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eChondroitin and Glucosamine are substances found naturally in the body, and in particular, in and around the cartilage and other connective tissues.Glucosamine falls within a class of compounds known as amino sugar, and is a precursor to a molecule called glycosaminoglycan.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eMethylsulfonylmethane (MSM)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMSM is a naturally occurring, organosulfur molecule that can be synthesized both naturally and synthetically from DSMO. While the majority of MSM present in the human body is ingested – either deliberately or accidentally – the compound does have a natural presence in certain tissues and fluids in the body, including cerebrospinal fluid. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCissus quadrangularis\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCissus quadrangularis (CQ) is a plant with a long history of use in traditional and folk medicinal systems, including thousands of years of documented use in the Siddha and Ayurvedic traditions. While the specific use of Cissus in these systems varied, the most common traditional preparations related to analgesia, general tonics, and bone fracture healing.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBlack cherry extract\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBlack cherry extract contains a number of beneficial compounds, including high levels of anthocyanin – an extremely potent anti-inflammatory compound which some animal evidence has shown plays a role in the maintenance of articular jointsIt is rich in antioxidants and catechins, chlorogenic acid, and flavonal glycoside, and has been used to support healthy uric acid levels typically associated with complete joint health.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eTurmeric (95% curcumin)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTumeric is a root endemic to certain regions of Southeast Asia and India, and has been a staple in the Siddha traditional medicinal system for thousands of years. \u003c\/p\u003e\n\u003cp\u003eMore recently, numerous studies seem to suggest that its primary bioactive constituent, curcumin,  powerfully inhibits the enzymes that synthesize inflammatory compounds such as prostaglandins and leukotrienes.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBoswellia (37.5% boswellic acids)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSimilarly to curcumin, boswellic acids have demonstrated a significant attenuation of NF-kB production in various animal and\u003cspan\u003e \u003c\/span\u003e\u003cem\u003ein vitro\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003eassays.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBromelain (2400GDU\/g)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBromelain is a collection of protein-digesting enzymes found in pineapple juice and in the stem of pineapple plants. It has been shown to have a myriad of health benefits including speed of recovery, antioxidant properties, and assisting cardiovascular and circulatory health.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin C\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVitamin C is not only a powerful antioxidant, but also supports a healthy immune system, protects cells from oxidized particles and free radicals, and assists other physiological functions. \u003cstrong\u003eVitamin D3\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin D3 is an essential hormone precursor that plays a vital role in many metabolic functions, including bone health, , immune and cardiovascular health, muscle protein synthesis, and weight management. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003ePiperine (95%)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePiperine a black pepper extract, is included because it dramatically increases the bioavailability of curcuminoids.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":44380541583602,"sku":"coreflex","price":44.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/products\/Core-Flex.jpg?v=1677369629"},{"product_id":"core-peak","title":"Core Peak","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Peak\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eThe formulation of Core PEAK promotes a unique form of localized blood flow, known as a performance pump, which is increased blood flow with a purpose. What is that purpose? PEAK utilizes multiple metabolic pathways to provide demonstrable and significant improvements to key markers known within the field of exercise physiology, including, but not limited to, total time to exhaustion, peak power, total work capacity, protein synthesis and muscle hypertrophy. This is accomplished through the inclusion of research-backed ingredients that not only enhance what’s referred to as the “pump effect” or increased volume and vascularity, but also exhibit noticeable improvements to key performance metrics.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eArginine Nitrate (N03-T®)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNitric oxide (NO) is involved in many vascular and cellular functions as a signaling molecule for cellular respiration, vasodilation, and angiogenesis. NO is produced through both endogenous and exogenous pathways through dietary nitrate ingestion. Nitrates are converted to nitrite, which is then converted to nitric oxide. Found naturally in many foods such as leafy greens and beets, NO has a long history of scientific literature to back its potential effects as an ergogenic aid and other health-promoting effects. In terms of athletic performance, NO typically will make an impact through a few different mechanisms, such as:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eDelayed onset of fatigue\u003c\/li\u003e\n\u003cli\u003eIncreased nutrient and oxygen delivery to working muscles via increased vasodilation\u003c\/li\u003e\n\u003cli\u003eIncreased loss of metabolic by-products as a result of high intense exercise\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eHowever, when it comes to exercise and utilizing NO for its benefits in athletic performance, consuming whole foods is not always the most optimal form, so dietary supplemental forms of nitrates are often used to help provide this benefit. There are several forms of supplemental nitrates on the market today but for Core PEAK we are utilizing arginine nitrate (NO3-T®). Arginine nitrate is a salt that is synthesized from adding nitric acid to arginine. Arginine is classically utilized for its blood flow and vasodilation improving benefits and when combined with a nitrate, these benefits get exponentially elevated. As discussed above, the pathways with which NO is produced are of the importance. Pairing arginine with the patented nitrate (N03-T®) enhances nitric oxide production via the nitrate-nitrite pathway. Organic nitrate esters have a direct relaxant effect on vascular smooth muscles through non-nitric oxide synthase pathways, being directly converted first to nitrites and then to nitric oxide itself. (With attendant increases to guanylyl cyclase and then cyclic guanosine monophosphate (cGMP), which relax the vasculature.) Pairing both nitric oxide synthase and non-nitric oxide synthase-dependent mechanisms of actions theoretically enhances total NO production, given that rate-limiting enzymatic pathways in either mechanism do not determine total NO production.\u003c\/p\u003e\n\u003cp\u003eIn an absolute sense, both inorganic and organic nitrates also possess benefits beyond a secondary NO-production pathway. Studies in athletes have demonstrated that nitrate ingestion prior to both aerobic and anaerobic exercise meaningfully increases both delay to fatigue and total work capacity – likely a consequence of nitrate’s activation in hypoxic (oxygen-deprived tissues). Nitrate effectively reduces the oxygen cost of muscular activity, making contractions more efficient.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVasoDrive-AP®\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVasoDrive-AP® is a proprietary ingredient derived from fermented casein. The fermentation process produces two lactotripeptides, Valyl-Prolyl-Proline (VPP) and Isoleucyl-Prolyl-Proline (IPP). Based on the available clinical evidence, these tri-peptides work together to reduce angiotensin converting enzyme (ACE).\u003c\/p\u003e\n\u003cp\u003eIn a recent meta-analysis researchers found 30 studies – all of which were randomized and some of which were double-blind – wherein Valyl-Prolyl-Proline (VPP) and Isoleucyl-Prolyl-Proline (IPP), either alone or in combination, exerted a statistically significant effect on improving endothelial function. In one of the analyzed studies, 25 men were challenged with casein hydrolysate standardized for tri-peptides in a randomized and placebo-controlled design. At the conclusion of the study, forearm blood flow, a key measure of endothelial function, was found to be increased by 33%. The researchers in this and other studies demonstrate that the tri-peptides that constitute VasoDrive-AP® exert an inhibitory effect on ACE. ACE, in turn, is a critical component of the renin-angiotensin (RAS) system, which regulates hemodynamics by controlling plasma fluid volume. While the precise mechanism has not been elucidated, researchers believe that the lactotripeptides in VasoDrive-AP® competitively inhibit ACE, thus decreasing the metabolism of bradykinin and systematically dilating the arteries and veins.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePEAK ATP®\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAdenosine 5’-triphosphate (ATP) is the single most important molecule for our body’s cells. Every single cell in the human uses ATP as its primary source of energy for processes such as ion transport, muscle contraction, nerve impulse propagation, DNA\/RNA synthesis, and chemical reactions withing the body. Our body stores ATP and can produce ATP through the presence of oxygen from cellular respiration, the breakdown of foods ingested, as well as under certain anerobic conditions. Maintaining high levels of ATP are essential to continuously perform at optimal levels both in a physical and physiological way. This is important because its not just about ATP availability but the timing and localization of ATP can be essential for the success of multiple physiological and metabolic actions. Knowing this, ingesting forms of ATP have been on the rise recently in the nutraceutical industry. Peak ATP® is a revolutionary innovation as a clinically validated and patented form of adenosine 5’-triphosphate disodium, which is the only nutritional ingredient that has an identical structure to the same ATP produced and utilized by the human body. Now for the common individual, ATP supplementation may not pose much of a benefit as their typical daily life and nutrition is likely sufficient, but for the individual engaged in heavy and intense physical activity and exercise the demand for ATP and useable energy at the ready is essential to performance and continuing to perform at a high level as well as recovering optimally. The demand for ATP in these cases can be increased up to 1000-fold during exercise and the rate at which ATP is broken down can limit performance.\u003c\/p\u003e\n\u003cp\u003ePeak ATP® helps to provide this readily available form of ATP as a highly bioavailable form of useable energy that potentiates the role of ATP in the human body. In relation to exercise, this equates to allowing for the potential of athletes to do more and achieve more, with much less fatigue. Peak ATP® also has been shown to benefit athletic performance through enhancements in:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eVasodilation and increasing blood flow by up to 54%.\u003c\/li\u003e\n\u003cli\u003eCalcium metabolism in muscle, which is essential for muscle contractions\u003c\/li\u003e\n\u003cli\u003eERK-mTOR pathway, which is the pathway that promote protein synthesis and muscle hypertrophy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt’s a known subject that ATP is essential to the human body and its processes and maintaining high levels is of the utmost importance for optimal functioning. During increased energy needs these ATP pools naturally in the body can be depleted rather quickly, leading to less-than-optimal functioning and overall resulting factors. Peak ATP® has been shown to stimulate greater ATP production, decrease declines in ATP pools, and allow for greater energy usage potential. Peak ATP® can allow anyone get more out of their body by providing the needed energy to perform at a high level.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCitraPeak® Glucosyl-Hesperidin (from modified Citrus aurantium and Citrus sinesis Fruit Extracts)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCitraPeak®, or glucosyl hesperidin, is a unique substance that contains all of the biological functions of standard hesperidin. Hesperidin is a flavonoid commonly found in citrus fruit peels. It has shown capabilities in a clinical setting of increasing nitric oxide production, which has the ability to improve circulation. One study demonstrated this through skin color restoration as a result of the increased blood flow and NO production as well as a mild increase in body temperature as a result. Both of these effects can be noteworthy of the vasodilatory actions taking place. CitraPeak® offers these benefits with increased solubility and bioavailability, making it one of the most effective forms of hesperidin there is.\u003c\/p\u003e\n\u003cp\u003eThe proposed mechanism of action for CitraPeak® and hesperidin is that it can acutely stimulate phosphorylation of Src, Akt, AMP kinase, and endothelial NO synthase to produce NO through the metabolism of hesperetin in the body. This increased NO production, while beneficial from a muscle performance standpoint, can also have a positive effect on other factors as well. Clinical studies have shown that hesperidin can increase flow mediated dilation and reduced concentrations of circulating inflammatory biomarkers, such as C-reactive protein, serum amyloid A protein, and soluble E-selectin. So, in addition to the exercise performance benefits that hesperidin can provide, it also has been shown to have positive vasculoprotective actions that can benefit the cardiovascular and circulatory system.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":44536053793010,"sku":"corepeak","price":54.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/core-peak_1800x1800_180bf726-6f4e-4c8b-bc1e-61ce68fa617d.jpg?v=1686042145"},{"product_id":"core-nutritionals-abc-aminos","title":"Core Nutritionals ABC Aminos","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutritionals ABC Amino Acids\u003c\/h2\u003e\n\u003cp\u003eCore Nutritionals ABC contains BCAA's and other amino acids that may aid in recovery. 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Amino acid products with a caffeine or energy component are very popular these days. There’s only one problem: almost none of them contain a solid serving of amino acids, and most don’t contain BCAAs at all! Don’t get us wrong, we love EAAs – but when you think “amino acid product,” are you really thinking cysteine? Us neither.\u003c\/p\u003e\n\u003cp\u003eSo, in classic Core style, they did something about it: we created Core ABCD, the amino and caffeine product with actual BCAAs, at a full serving size. But we of course didn’t stop there. We included CarnoSyn® beta-alanine, to provide you muscle energy and endurance – along with the caffeine in our Drive™ energy blend. Core included N-Acetyl-Tyrosine for all its important roles in metabolism and neurohormone production. We included Acetyl-L-Carnitine, to keep that carbohydrate and fat metabolism rolling. And of course, Core included not only caffeine (which all the other guys do), but also choline bitartrate – to enhance focus along the way.\u003c\/p\u003e\n\u003cp\u003eCore ABCD is the premiere and most complete product in its category, hands down. No product of its type offers as much for such little cost: it’s an energy product, an endurance product, and a complete amino acid product all in one.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"30 Servings \/ Sweet Tea","offer_id":44542201331954,"sku":"coreabcd","price":29.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/ABCD-Sweat-Tea.jpg?v=1686559911"},{"product_id":"core-bolic-v2","title":"Core Bolic V2","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Bolic V2\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCore Bolic V2 is a great upgrade to Core Nutritionals natural muscle builder. Core Bolic V2 is an innovative fusion of heavily studied ingredients meticulously crafted to elevate your capabilities. At its core are three remarkable components: PeptiStrong™, Maral Root Extract, and Camellia sinensis Extract, (fortified by the bioenhancing prowess of BioPerine®. Together, these elements unlock a world of possibilities that extend beyond the ordinary.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eCore Bolic V2 Highlights\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eCan Increase Muscle Protein Synthesis\u003c\/li\u003e\n\u003cli\u003eMay Increase Lean Body Mass\u003c\/li\u003e\n\u003cli\u003eCan Improve Athletic Performance\u003c\/li\u003e\n\u003cli\u003eCan Boost Recovery \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Bolic V2 Supp Facts\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eFava Bean (Vicia faba) Hydrolysate (as PeptiStrong™)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePeptiStrong™ is an ingredient derived from fava beans that contains extremely beneficial natural compounds called bioactive peptides. Other sources of naturally occurring bioactive peptides are collagen, insulin, and glutathione, all of which have crucially beneficial properties. These peptides have undergone patent protection and extensive research, including both pre-clinical and clinical studies. The studies have shown positive effects on gene expression and the secretion of tumor necrosis factor alpha (TNF-a). In vitro experiments using murine skeletal muscle cells and human macrophages have validated the ability of the peptides within PeptiStrong™ to increase muscle protein synthesis and reduce TNF-a secretion. The study also assessed the bioavailability and stability of the peptides, which proved to be resistant to digestion, displayed good intestinal barrier transport, and remained stable in plasma.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eMaral Root Extract (Rhaponticum carthamoides) (10:1)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMaral Root Extract, derived from the plant Rhaponticum carthamoides, is a natural ingredient highly regarded for its adaptogenic properties and numerous health benefits. This herb has a rich history in traditional medicine and is known for its ability to enhance physical and mental performance, support stress resilience, boost energy levels, promote vitality, improve athletic performance, and aid in post-exercise recovery. One crucial aspect of athletic performance is the ability to maintain a high capacity throughout the event and be able to then recover efficiently. Maral Root Extract has shown potential in addressing both of these aspects. Let's first examine how this herb can enhance measures of athletic performance.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCamellia sinensis Extract (Bean) (std. to 90% Epicatechin)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEpicatechin is a plant-based phytochemical, or flavanol, that is found in trace amounts in foods and liquids such as dark chocolate and green tea. Its physiological benefits have been studied for years and have resulted in promising results in relation to:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEnhanced muscle growth and strength\u003c\/li\u003e\n\u003cli\u003eIncreased nitric oxide production (better pumps)\u003c\/li\u003e\n\u003cli\u003eLowered cholesterol levels due to antioxidant content\u003c\/li\u003e\n\u003cli\u003eImprovements in brain and heart health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese proposed benefits listed above and the compelling research surrounding them has led epicatechin to be involved in innovations where muscle growth and improved performance are the goal.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBioperine® (Piper nigrum) (Fruit) (std. to 95% Piperine)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBioPerine® is a patented standardized extract from the fruit of Piper nigrum (black pepper). It’s studied benefits have shown improvements in bioavailability of nutrients it is surrounded by.\u003c\/p\u003e\n\u003cp\u003eBioPerine® primarily works through mechanisms and channels that can inhibit intestinal motility and dilate blood vessels of the intestines (where absorption of nutrients occurs). This physiological action may cause increased absorption and digestion of nutrients.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":44742030131442,"sku":"corebolicv2","price":61.49,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/corebolicv2.jpg?v=1697846363"},{"product_id":"core-hydration-packets","title":"Core Hydrate","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Hydrate\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eHydration is one of the most important factors in athletic performance. Yet, many of the mass marketed “sports drinks” widely available today fail to properly address the issues posed by sustained periods of intense exercise. A broad base of research demonstrates that proper hydration and electrolyte levels can delay fatigue, increase endurance, reduce delayed onset muscle soreness, and increase a wide-range of athletic performance metrics.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003e\u003cmeta charset=\"utf-8\"\u003eCore Hydration Highlights\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eAvoiding premature fatigue and muscle failures\u003c\/li\u003e\n\u003cli\u003eReenergizing and rejuvenating cells\u003c\/li\u003e\n\u003cli\u003eProtecting against free radical damage\u003c\/li\u003e\n\u003cli\u003eIncreasing endogenous ATP production\u003c\/li\u003e\n\u003cli\u003eEnhancing power output, strength, and overall athletic performance\u003c\/li\u003e\n\u003cli\u003eImproving stamina and recovery time\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Blend of Electrolytes\u003c\/strong\u003e- Can replace key electrolytes lost during intense training.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElevATP\u003c\/strong\u003e®- Can increase levels of endogenous ATP.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSenActiv\u003c\/strong\u003e®- Can promote muscle energy and regeneration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003e\u003cmeta charset=\"utf-8\"\u003eCore Hydration Supp Facts\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eVitamin C (as ascorbic acid)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVitamin C is perhaps historically best-known for the treatment and prevention of scurvy, though it has many other roles in the body. For example, vitamin C catalyzes or is a cofactor in eight enzymatic reactions involved in the synthesis of collagen, the nutrient carnitine, and several neurotransmitters necessary for the proper function of the brain.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCalcium (as calcium carbonate, calcium citrate, dicalcium malate (DimaCal®))\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhile best-known as the main bioactive in milk, and a compound that contributes to strong bones, calcium has numerous physiological effects in the body. As a key electrolyte it is responsible for mediating vascular contraction and vasodilatation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion. Homeostatic regulation of calcium, which the body cannot produce, also requires sufficient levels of vitamin D. In the context of muscular contraction and relaxation, if calcium is required for strong contractions, magnesium is required for efficient relaxation of those muscle fibers.\u003c\/p\u003e\n\u003cp\u003eDimaCal® is a trademarked form of dicalcium malate, which is calcium bonded with malic acid. It has been shown in studies to be a much better absorbed form of calcium and has the ability to maintain serum calcium levels for a much longer period of time. This can lead to a better maintained electrolyte level and greater performance where calcium is required.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eMagnesium (as magnesium carbonate, magnesium bisglycinate chelate (TRAACS®), magnesium citrate, magnesium glycinate glutamine chelate (TRAACS®))\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMagnesium, an often-overlooked electrolyte, is the second most abundant intracellular cation (after potassium). It is a cofactor to over 300 enzymatic reactions in the body and is required for cellular energy metabolism, functioning of the sodium\/potassium adenosine triphosphatase pump, nerve conduction, and ion transport. Magnesium is also required for the use of the body’s energy currency, ATP. To become biologically active, ATP must be bound to magnesium to form Mg-ATP. In addition, magnesium is necessary for the proper function of cells with calcium and potassium gated ion channels such as heart and muscle cells. Working alongside calcium, magnesium plays a crucial role in the body by regulating muscular contractions as well as cramp prevention. In the context of muscle health and rehydration, the longer and more intense a bout of physical activity is, the more magnesium is lost primarily through sweat and urine. This loss of electrolyte balance requires its replenishment so that physical performance can remain at its peak throughout the duration of the activity reducing the risk of injury or bodily harm. Regardless of the type of sport or exercise, muscular contractions and energy production could not occur consistently without the presence of magnesium.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eZinc (as zinc bisglycinate chelate (TRAACS®))\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAs an essential mineral, like magnesium, zinc is also involved in a wide-range of essential biological functions in the human body – and a requirement in the catalytic activity of over 100 enzymes.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eChloride (as sodium chloride, potassium chloride)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eChloride is one of the most important electrolytes in the human body. Similar to sodium and potassium, which will be discussed below, chloride creates specific channels in cell membranes which help to carry out different vital tasks. It is responsible for balancing the fluids on the inside of the cells with the fluids on the outside of the cells, as well as maintaining proper blood volume, blood pressure, and fluid pH. Chloride is also important for muscle and heart contraction as well as to aid in the carrying of nerve impulses between our nerve cells and our brain and the rest of the body. Additionally, chloride is needed to help red blood cells exchange oxygen and carbon dioxide in the lungs as well as plays a role in the digestion of foods by supporting hydrochloric acid production in the stomach. We often lose chloride through sweat and perspiration, which comes in the form of water and salt. Replenishment of chloride can come from utilizing salt (often found as sodium-chloride, or table salt), cheese, canned fish, and some processed meats. Overconsumption of some of these foods may not be beneficial for some individuals, so supplementation may be the best way for these individuals to replenish chloride in their bodies.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eSodium (as sodium chloride, sodium citrate, sodium bicarbonate)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSodium, like chloride above, is one of the most essential electrolytes for our body to utilize. As sodium is often found bound to chloride as sodium-chloride (salt), their function and benefits are going to be very similar in nature. Sodium helps to keep the water (mainly amount of fluid outside of the body’s cells) and electrolyte balance of the body, while also aiding in the contraction and relaxation of muscles as well as conducting nerve impulses. While only 500mg of sodium is needed per day for these functions to occur, we as active individuals need far more sodium in order to maintain these functions. We mostly lose sodium through sweat and urine, so the more active we are\/the more we sweat and the more we urinate, the more sodium is lost. Acquiring enough sodium through food and drink is crucial to establishing equilibrium again in order to maintain proper functioning and electrolyte balance within the body. The standard American diet is often overloaded with sodium and coupled with inactivity, which can lead to poor health and dysfunction. It is important to engage in physical activity of some kind most days and to eat a diet that is balanced in nutrients in order to maintain proper health.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003ePotassium (as potassium citrate, coconut water concentrate, potassium chloride, potassium glycinate chelate (TRAACS®))\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePotassium, as sodium’s counterpart, acts as a critical electrolyte primarily by helping to maintain normal levels of fluids inside of our cells. Additionally, it helps muscles to contract and relax, aid in strong nerve function, as well as support normal blood pressure. It works very closely with sodium to create the membrane potential needed for the electrical currents that generate these functions to pass from one cell to the next. While the potassium levels in our body are regulated carefully, a diet lacking sufficient amounts of potassium (especially when combined with excess sodium) or one that contains too much potassium can eventually lead to certain types of dysfunctions and poor health status. When potassium levels in the body increase, the adrenal glands release the hormone aldosterone, which causes the kidneys to excrete excess potassium through the urine. When potassium levels are too low, aldosterone levels are suppressed, which can lead to conservation of potassium thus interfering with balance and negatively affecting transport channels that affect vital bodily functions. Potassium can be gotten from the diet in the form of fresh fruits and vegetables, such as sweet potatoes, beans, tomatoes, spinach and broccoli but supplementing can be an essential application as well to support an active lifestyle where excretion is higher than can be replenished through diet.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eL-Taurine\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough traditionally referred to as an amino acid due to its chemical structure, taurine is not an amino acid in the sense that leucine, alanine, or glutamine are. Its chemical status aside, taurine is considered one of the body’s most essential chemical compounds, as cardiovascular function, muscle development and function, along with optical and nervous systems in the body depend on its abundance. While data on taurine typically occurs with taurine in supplement combinations (with caffeine and other amino acids), these data nevertheless suggest that dietary supplementation with taurine may have beneficial effects on mental focus and alertness and may assist during times of increased physical exertion.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCoconut Water Concentrate (Cocos nucifera)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCoconut water, like the name implies, is the liquid that is found within the coconut itself. Often having a slightly sweet, nutty flavor, it also contains an adequate amount of vitamins, minerals, and electrolytes like potassium, sodium, and magnesium. All of these electrolytes, like discussed in sections above, can help to boost hydration status and replenish nutrients lost through exercise or rigorous everyday activities. Potassium is the highest concentration in coconut water at roughly 600mg per cup (16% DV), which as discussed about it has a vital role in optimally functioning kidneys and strong muscle contractions. Potassium can also work to keep fluid levels and other electrolytes balanced during exercise. The high concentration of potassium in coconut water specifically can balance our sodium’s effects on blood pressure, and even lower blood pressure slightly, which can have its own benefits towards training and overall health and circulatory health. In addition to the added electrolytes that coconut water can provide, it also can provide a potent amount of antioxidants that can aid in the neutralization of free radicals that can rapidly take over during intense training. By eliminating these free radicals, muscles will be able to perform longer and more efficiently, as well as be able to recover adequately. While general water consumption can be adequate as well, the added electrolytes coconut water can supply provides an added benefit that can improve performance and overall recovery.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eElevATP® (Ancient Peat and Apple Extract)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAdenosine triphosphate and other ATP metabolites are involved in a number of biological processes including cardiac function, blood flow, muscle contraction and neurotransmission. ATP is the primary molecule that acts as a carrier for energy within cells. It has also often been studied those increased levels of ATP have shown increases in health and performance. Supplementation with exogenous ATP has often shown its ability to increase ATP concentrations in blood. Oral supplementation with ancient peat and apple extracts have exhibited their ability to increase intracellular and intramuscular ATP levels. ElevATP® is a blend these specific polyphenols that can work to increase endogenous ATP levels without a simultaneous increase in serum lactate. The significance of this is that usually with an increase in endogenous ATP there is an increase in intracellular free radicals. When these free radicals are not present, oxidative stress is mitigated and there is more potential for the beneficial increases in ATP to take center stage. These increases of ATP are essential as when available energy is increased it can have positive benefits in terms of increased power, strength, and overall exercise performance. One study in particular looked at dosing ElevATP® against placebo and showed that the group who received ElevATP® saw a blood ATP increase of 45% on average along with no increase in oxidative blood glucose. This type of result has been shown repeatedly in studies and has given ElevATP® the reputation to be a beneficial compound for the goals of improving endurance, strength, power, and other training specific adaptations.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eConcenTrace® AC (Trace Mineral Complex)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOur bodies are high functioning machines and require a lot of support to continue to perform at a high-level day in and day out. A lot of these needs are difficult to be acquired by diet alone, so supplementation is critical. Minerals are included in these daily needs and are vital to the bodies many processes. ConcenTrace® AC is a high-quality trace mineral complex providing a comprehensive blend of nutrients that are often hard to acquire from diet alone. Its manufacturing process makes it up to 26x more concentrated than other colloidal trace minerals, adding to its benefits. These minerals contained in the product are catalysts for all of the vitamins and other nutrients our body requires to function at an optimal level and maintain health. Some of these functions include electrolyte replacement, maintaining pH balance in the body, nourishing hair and skin, strengthening bones and joints, regulating the digestive system, and improving athletic performance.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eSenactiv® (Panax notoginseng (root) and Rosa roxburghii (fruit)) Extracts\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSenactiv®, derived from extracts of Panax notoginseng and Rosa roxburghii, has been shown to act in a few pathways to reenergize and rejuvenate cells within the body that take a beating on a daily basis. Ultimately this product falls within a category known as senolytics, or compounds that primarily work to induce cell death. This may not sound ideal as we need our cells to function, but the key is to ensure that these compounds are working on the right kinds of cells.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"1 Box (20 Packets) \/ Blue Ice","offer_id":46227972260082,"sku":"corehydratebice","price":32.99,"currency_code":"USD","in_stock":false},{"title":"1 Box (20 Packets) \/ Strawberry Margarita","offer_id":46227973112050,"sku":"corehydratestwmgr","price":32.99,"currency_code":"USD","in_stock":false},{"title":"1 Box (20 Packets) \/ Cherry Berry (Best By 09\/25)","offer_id":44742037668082,"sku":"corehydrate-3","price":24.99,"currency_code":"USD","in_stock":false},{"title":"1 Box (20 Packets) \/ Blue Raspberry (Best By 09\/25)","offer_id":44742037700850,"sku":"corehydrate-4","price":24.99,"currency_code":"USD","in_stock":false},{"title":"1 Box (20 Packets) \/ Orange Cream (Best By 09\/25)","offer_id":46699645927666,"sku":"corehydrate-8","price":24.99,"currency_code":"USD","in_stock":false},{"title":"20 Serving Tub \/ Dill Pickle","offer_id":47449145901298,"sku":"corehydratedillpickle","price":29.99,"currency_code":"USD","in_stock":false},{"title":"1 Packet \/ Cherry Berry (Best By 09\/25)","offer_id":44742037569778,"sku":"corehydrate-1","price":1.5,"currency_code":"USD","in_stock":false},{"title":"1 Packet \/ Blue Raspberry (Best By 09\/25)","offer_id":44742037635314,"sku":"corehydrate-2","price":1.5,"currency_code":"USD","in_stock":false},{"title":"1 Packet \/ Orange Cream (Best By 09\/25)","offer_id":46699647500530,"sku":"corehydrate-9","price":1.5,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/core-picke-front_1800x1800Large.jpg?v=1743927820"},{"product_id":"core-grow-mass-gainer","title":"Core Grow Mass Gainer","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cdiv class=\"product-template__container style1 page-width\" data-style=\"style1\" id=\"ProductSection-product-template\" data-section-id=\"product-template\" data-section-type=\"product\" data-enable-history-state=\"true\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"tabs-listing wow fadeIn\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"tab-container\" data-mce-fragment=\"1\"\u003e\n\u003cdiv id=\"tab1\" class=\"tab-content\" data-mce-fragment=\"1\"\u003e\n\u003ch2 style=\"text-align: center;\" data-mce-fragment=\"1\"\u003eCore Grow Mass Gainer Protein Powder\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCore GROW does and is hands down, flat-out, the most complete, soundest gainer on the market with the highest quality ingredients. There are no flashy “new carb” technologies in GROW – there is only a whole food-based carb blend derived from the foods you are already eating. Quick: name a fitness staple for carbs. You answered oats, and so did we. That is why oatmeal flour is the cornerstone of our carbohydrate blend – along with sweet potato flour and natural cane sugar.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eComplete proteins? How about cold-processed, undenatured whey protein concentrate and milk protein isolate. Not only are you consuming the king of proteins but you are not going to have to choke this mass gainer down either due to off putting texture.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHealthy fats? How about coconut oil powder, a nutritional powerhouse and one of the best fat sources you can find.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eGot enzymes? That is right, to help you digest this meal in a scoop, we’ve included an industry-best enzyme blend. Not to mention that nearly every ingredient in our formulation has a vitamin, mineral, and micronutrient profile that would make a dietician blush with envy.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eFinally, we want to make sure you are truly making quality gains with this mass gainer. That is why we included patented Velositol® in this formulation to make sure you are maximizing your muscle protein synthesis and reaping the maximal benefits of all of these quality ingredients.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eGrowing and gains should fit into your life, not pose a problem to it. Core GROW is a gaining solution that factors in the reality that people taking it still live a life, still have a diet, and need a gainer that occupies a beneficial place in them. We said above that this is the best gainer on the market, and we meant it. Now you simply need to grab some GROW and see for yourself.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"page-width bottom-addtocart\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"product-form mfp-link\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"swatch clearfix option1\" data-option-index=\"0\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"product-form__item\" data-mce-fragment=\"1\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Core Nutritionals","offers":[{"title":"10 lbs \/ Cookies and Cream","offer_id":44903428456690,"sku":"coregrow-1","price":89.99,"currency_code":"USD","in_stock":true},{"title":"10 lbs \/ Chocolate PB Cup","offer_id":44903428522226,"sku":"coregrow-2","price":89.99,"currency_code":"USD","in_stock":true},{"title":"10 lbs \/ Vanilla Milkshake","offer_id":44903428554994,"sku":"coregrow-3","price":89.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/grow-cookies-n_cream_1800x1800_38245add-283c-4f42-9be6-e3223c7f79b7.jpg?v=1700691554"},{"product_id":"core-brownies","title":"Core Brownies","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Brownies\u003c\/h2\u003e\n\u003cp\u003eCore Nutritionals has done it again! They have collaborated with Moose Tracks to make epic brownies.\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCompletely homemade, these treats feature authentic Moose Tracks® peanut butter cups, famous fudge pieces, as well as swirls of iconic Moose Tracks® fudge through the rich, chewy texture of every brownie and blondie,ensuring every bite is bursting with Moose Tracks® recognizable flavor. Satisfy your sweet tooth and fuel your day with this decadent twist on a classic favorite and enjoy the amazing experience of Moose Tracks® no matter where you are.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eCore Brownies Highlights\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e16 Grams of Protein Per Brownie\u003c\/li\u003e\n\u003cli\u003eAuthentic Moose Tracks® Inclusions\u003c\/li\u003e\n\u003cli\u003eIconic Moose Tracks® Fudge Swirl\u003c\/li\u003e\n\u003cli\u003eHomemade Baked Treat\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e12 brownies per box\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Core Nutritionals","offers":[{"title":"1 Brownie \/ Blonde","offer_id":44903528825074,"sku":"corebrownies-1","price":3.49,"currency_code":"USD","in_stock":false},{"title":"1 Brownie \/ Chocolate Brownie","offer_id":44903528857842,"sku":"corebrownies-2","price":3.49,"currency_code":"USD","in_stock":false},{"title":"1 Box (12 Brownies) \/ Blonde","offer_id":44903528890610,"sku":"corebrownies-3","price":39.99,"currency_code":"USD","in_stock":false},{"title":"1 Box (12 Brownies) \/ Chocolate Brownie","offer_id":44903528923378,"sku":"corebrownies-4","price":39.99,"currency_code":"USD","in_stock":false},{"title":"1 Brownie \/ Banana PB Blondie","offer_id":45338210697458,"sku":"corebrownies-1pbb","price":3.49,"currency_code":"USD","in_stock":false},{"title":"1 Box (12 Brownies) \/ Banana PB Blondie","offer_id":45338215055602,"sku":"corebrownies-4pbb","price":39.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/BananaPB-MT-ProteinBlondie-Front_1800x1800_fb869663-8922-41d9-b120-9412c81c794d.jpg?v=1710059172"},{"product_id":"core-iso-clear","title":"Core Iso Clear","description":"\u003cp\u003e \u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003eCore Iso Clear - Clear Whey Protein Isolate\u003c\/h2\u003e\n\u003cp\u003eIntroducing Cores' latest innovation, Fun Sweets Cotton Candy® Clear Whey Protein Isolate! Elevate your protein intake with this unique blend that not only packs a powerful punch of 24g of high-quality whey protein isolate per serving but also indulges your taste buds with the authentic and delicious essence of classic cotton candy. Treat yourself to a new kind of post-workout experience that combines the best of both worlds—efficacious protein to support your muscle recovery and the unmistakable sweetness of cotton candy to make each sip an experience worth celebrating. With its crystal-clear formulation and vibrant flavors, this whey protein isolate takes post-workout nutrition to a whole new level, ensuring that your fitness journey is not only effective but also deliciously fun. But don't think you can only enjoy these amazing flavors after a grueling workout. You can savor the sweet taste of Fun Sweets® ISO Clear any time! So, get ready to redefine your protein game with the amazing flavors of Fun Sweets Cotton Candy®, where smiles are always guaranteed!\u003c\/p\u003e\n\u003cp\u003eWe all know that whey protein is one of the most utilizes protein sources on the market. With its convenient nature and wide variety of flavors that it can take on, it is a common and popular option for many people looking to put on muscle or just increase their overall protein intake. Unfortunately, with whey protein classically have a milky taste, it lends itself useful for taking on primarily sweet, dessert like flavors, like chocolates, vanillas, peanut butters, and other classic ice cream varie ties. Recently there has been an uptick in innovation in the whey protein category with the introduction in clear whey protein isolate.\u003c\/p\u003e\n\u003ch3\u003eCore Iso Clear Highlights\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003e24g of Whey Protein Isolate\u003c\/li\u003e\n\u003cli\u003eComplete Amino Acid Profile\u003c\/li\u003e\n\u003cli\u003e0g Sugar\u003c\/li\u003e\n\u003cli\u003eAuthentic Fun Sweets Cotton Candy® Flavors\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Iso Clear Supp Facts\u003c\/h3\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/ISO_CLEAR_480x480.jpg?v=1755753435\" alt=\"\" style=\"float: none; display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/div\u003e\n\u003ch3\u003eCore Iso Clear FAQ\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eWhat is clear whey? \u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eClear whey protein is still derived from whey, but what sets clear whey protein apart is its unique processing method that removes fats and carbohydrates, resulting in a clear and transparent liquid. This form of whey protein offers a convenient and refreshing alternative to traditional whey protein powders, which as mentioned above, often have a milky taste and appearance. Even with this more rigorous processing method, clear whey protein still retains all the high - quality protein content of traditional whey, providing essential amino acids that support muscle recovery and growth. For individuals looking for a light and easily digestible protein source, but having a more juice like consistency and flavor profile, Clear Whey can be a great option. Core Nutritional’s® has finally entered the clear whey space with ISO CLEAR!Offering two amazing flavors wit h our partners at Fun Sweets Cotton Candy® you can now enjoy these sweet carnival flavors anytime, anywhere and reap the benefits of high quality and ultra-pure whey protein isolate!\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"About 19 Servings \/ Orange Cream (Fun Sweets)","offer_id":47865038438642,"sku":"coreisoclear-19oc","price":49.99,"currency_code":"USD","in_stock":true},{"title":"About 19 Servings \/ Blue Raspberry (Fun Sweets)","offer_id":47865039028466,"sku":"coreisoclear-br19","price":49.99,"currency_code":"USD","in_stock":true},{"title":"About 19 Servings \/ Cherry Berry (Fun Sweets)","offer_id":47865046302962,"sku":"coreisoclear-19cb","price":49.99,"currency_code":"USD","in_stock":true},{"title":"About 30 Servings \/ Orange Cream (Fun Sweets)","offer_id":46699635179762,"sku":"coreisoclear-3","price":59.99,"currency_code":"USD","in_stock":false},{"title":"About 30 Servings \/ Blue Raspberry (Fun Sweets)","offer_id":44950035857650,"sku":"coreisoclear-1","price":59.99,"currency_code":"USD","in_stock":false},{"title":"About 30 Servings \/ Cherry Berry (Fun Sweets)","offer_id":44950035890418,"sku":"coreisoclear-2","price":59.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/ISOCLEAR_ORANGE_FRONT_1800x1800_6e6881c4-df3c-41a3-824a-368947a53aea.jpg?v=1755753492"},{"product_id":"core-daily-health-pack","title":"Core Daily Health Pack","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Daily Health Pack\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCore Nutritionals packed a combination of micronutrients, omega-3, probiotics, greens and reds, and products to support vital joints and organs, that can be highly beneficial to their overall function. Overall, a convenient daily pack of these supplements can help individuals maintain their health, support key body functions, and optimize well-being, even during a hectic and unpredictable lifestyle.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eYou are getting a jack of all trades in terms of health support.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eCore Daily Health Pack Highlights\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eJack of all Trades of Health Supplements\u003c\/li\u003e\n\u003cli\u003eIncludes Vitamins, Greens, and Probiotic Health Support\u003c\/li\u003e\n\u003cli\u003eIncludes Joint Support \u0026amp; Omega 3 Health Support\u003c\/li\u003e\n\u003cli\u003eIncludes a Heart and Liver Health Support\u003c\/li\u003e\n\u003cli\u003eIncludes a Brain Health Support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Daily Health Pack Supp Facts\u003c\/h3\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/supplement-facts-DAILY-HEALTHLarge_480x480.jpg?v=1704945535\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eB Vitamins (Thiamine, Riboflavin, Niacin, B6 [Pyridoxine], Folic Acid, B12, Biotin, and Pantothenic acid)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eB vitamins are a group of eight essential vitamins with several critical functions in the body. Though both molecularly and physiologically distinct, they are also deeply interrelated in their effects, synthesis, and metabolism. Among the B-complex’s many critical roles are energy (protein, carbohydrates, and fat) metabolism, supporting and maintaining the healthy function of the adrenal glands, skeletal muscle function, and digestion.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin A (as retinyl palmitate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBeta carotene is itself not an essential vitamin but is rather the precursor to the fat-soluble and essential vitamin, vitamin A (Retinol). Like B vitamins, the term vitamin A refers to the compound class retinoids, comprised of retinol, retinal (also called retinaldehyde), retinoic acid, and provitamin A compounds such as beta carotene.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin C (as Ascorbic Acid)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin C is perhaps historically best-known for the treatment and prevention of scurvy, though it has many other roles in the body. For example, vitamin C catalyzes or is a cofactor in eight enzymatic reactions involved in the synthesis of collagen, the nutrient carnitine, and several neurotransmitters necessary for the proper function of the brain.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin D3 (as Cholecalciferol)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin D, in its various forms, is not an essential nutrient – as it is produced endogenously within the body, as a reaction to the skin’s exposure to the sun – and thus not commonly considered a vitamin. Despite its technical classification, vitamin D (a hormone), is nevertheless an import and biologically-active compound, necessary for the calcium homeostasis and metabolism, along with increasing the absorption of magnesium and phosphate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin E (as dl-alpha tocopherol acetate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin E is another technical misnomer, as the term refers to a group of compounds known as tocopherols with eight biologically-active constituents: alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol. Alpha-tocopherol is the principal bioactive in humans, though the presence of other tocopherols has been linked to beneficial effects.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCalcium (as dicalcium malate (DimaCal®)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhile best-known as the main bioactive in milk, and a compound that contributes to strong bones, calcium has numerous physiological effects in the body – including mediating vascular contraction and vasodilatation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion. Homeostatic regulation of calcium, which the body cannot produce, requires sufficient levels of vitamin D.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIodine (as potassium iodide)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIodine is a trace element naturally present in certain foods, including kelp. Iodine is a critical component for fetal development, especially during early pregnancy, as maternal T4 (thyroxine) is the sole source of fetal thyroid hormone. After birth, especially if breast-feeding, iodine remains an important constituent of a balanced-diet to maintain adequate T3 (triiodothyronine) and T4 (thyroxine) levels in the mother and for the proper cognitive development in the child.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMagnesium (as Di-Magnesium Malate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIt is difficult to overstate the biological necessity of magnesium. Magnesium is a co-factor in over 300 enzymatic reactions that regulate essential physiological functions such as protein synthesis, glucose homeostasis, muscle and nerve function, and the maintenance and support of healthy blood pressure levels.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eZinc (as Zinc Aspartate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs an essential mineral, like magnesium, zinc is also involved in a wide-range of essential biological functions in the human body – and a requirement in the catalytic activity of over 100 enzymes.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCopper (as Copper Bisglycinate Chelate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCopper is a trace element necessary for the production, function, and maintenance of a diverse range of compounds involved in physiological function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eManganese (as Manganese Citrate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eManganese is a required element for not only humans, but all living organisms. Manganese primarily acts as an antioxidant, specifically scavenging a radical oxygen species known as superoxide.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChromium (as Chromium Picolinate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eChromium is an essential, though little understood, trace element found in certain foods and industrial compounds. Only one of chromium’s two forms, the form used in Core MULTI, chromium 3+, is biologically active.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMolybdenum (as Molybdenum Glycinate Chelate)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMolybdenum is an essential trace element, involved in at least four enzymatic reactions necessary for urea excretion and several other physiological functions.\u003c\/p\u003e\n\u003ch3\u003eGREENS\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eChlorella and Spirulina Powder:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eChlorella and spirulina are the organisms behind the most common forms of green and blue\/green algae, respectively. Chlorella has been variously classified as either a plant or a protist, while spirulina is a kind of cyanobacteria and thus classified as a bacterium. Regardless of the taxonomical differences between chlorella and spirulina, emerging evidence suggests that both have a range of benefits for human health.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePhytoServ® Fruit Blend and Veggie Blend\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePhytoServ® is a proprietary blend of plant-based extracts that condenses voluminous micronutrient sources into easy to deliver clinical doses that provide powerful antioxidant containing phytonutrients that can protect the body’s immune system from the harmful effects of oxidative stress.\u003c\/p\u003e\n\u003cp\u003eIn the Fruit Blend you will receive a combination of:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eGrape Seed Extract\u003c\/li\u003e\n\u003cli\u003eWild Blueberry Extract\u003c\/li\u003e\n\u003cli\u003eRaspberry Extract\u003c\/li\u003e\n\u003cli\u003eCranberry\u003c\/li\u003e\n\u003cli\u003ePrune\u003c\/li\u003e\n\u003cli\u003eTart Cherry\u003c\/li\u003e\n\u003cli\u003eWild Bilberry Extract\u003c\/li\u003e\n\u003cli\u003eStrawberry\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIn the Veggie Blend you will receive:\u003c\/p\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eBroccoli Sprout\u003c\/li\u003e\n\u003cli\u003eOnion Extract\u003c\/li\u003e\n\u003cli\u003eTomato\u003c\/li\u003e\n\u003cli\u003eBroccoli\u003c\/li\u003e\n\u003cli\u003eCarrot\u003c\/li\u003e\n\u003cli\u003eSpinach\u003c\/li\u003e\n\u003cli\u003eKale\u003c\/li\u003e\n\u003cli\u003eBrussels Sprout\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eBRAIN\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAlpha-GPC 50%\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOf the known choline pro-drugs or precursors, Alpha GPC appears to have exert the greatest influence on circulating choline levels. Choline is an essential nutrient involved in numerous metabolic pathways, including DNA regulation and repair, protein function, and metabolism. Perhaps most importantly, the critical neurotransmitter acetylcholine is produced directly from free choline via cholinergic neurons. Acetylcholine is then responsible for several functions itself, most crucially as the compound which induces muscular contraction, and as the neuromodulator partially responsible for modulating risk\/reward, arousal, and enhancing memory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBacopa Extract (50% Bacopasides) (Bacopa monnieri L.) (Leaf)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBacopa monnieri, also known as the water hyssop commonly, or as Brahmi in Ayurvedic texts, is a small creeping herb endemic to sub-tropical India. The herb has been used in traditional Indian medicine for well over one thousand years, with its first recorded usage coming in the 6th century A.D. In this traditional context, \u003c\/p\u003e\n\u003cp\u003eBeyond cognition and memory encoding, BM has also been demonstrated to function as a potent adaptogen and relaxant – which in the Core DAILY HEALTH PACK brain formula may help to smooth the effect curve of the product’s stimulants, reducing jitteriness or, “crash.”\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoffee Fruit Extract (Coffea arabica) (Fruit) (CognatiQ®)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCognatiQ®, an extract derived from the whole fruit Coffea arabica plant, is a clinically proven ingredient shown to stimulate the production of the neuroprotein, Brain-Derived Neurotrophic Factor (BDNF). BDNF has been shown to be crucial in the development, maintenance and repair of neurons and also protect against neuro-degeneration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHuperzia serrata Extract (std. 1% Huperzine A)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHuperzia serrata is a compound found in the plant families of Huperziaceae, Lycopodiaceae, and Selaginella and is endemic to China. The Lycopodium alkaloid Huperzine-A, found in Core ZONE, was first isolated from a folk medicinal preparation in 1984.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"1 Box (30 Packets)","offer_id":45078382838002,"sku":"","price":69.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/daily-health-pack.jpg?v=1704945512"},{"product_id":"core-mrp-packs","title":"Core MRP Packs","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003ch2 style=\"text-align: center;\" data-mce-fragment=\"1\"\u003eCore MRP Packs\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCore MRP is designed with optimal results in mind. Cores' high quality, grain-sourced carbohydrates, multiple (and rich) protein sources, premium flavors, and a plethora of extras all come in a gourmet-tasting, instantized powder.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003ePop quiz: what’s the absolute, without question, most critical component to achieving those roadmap veins and granite abs you have always wanted? How hard and how frequently you work your abs? The intensity of your cardio training, maybe; or the HIIT training you’ve been doing? If you said any of the above, you’re wrong – while exercise is a critical component of achieving your body composition goals, the diet remains king.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eWhile it remains the most important component in a healthy lifestyle, a finely-tuned diet is often a difficult and impractical thing to implement. The most dedicated among us – and probably you, too – pack our fridge with Tupperware so high that chicken and plastic starts bursting through the freezer. We’ve all had the, “I eat this because...” conversation while at work, lugged our preferred food items to school, work, the park, and everywhere in between, and cursed the fact we went anywhere ill-prepared that day. There needs to be an easier – but equally effective – way, doesn’t there?\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eWell, at Core Nutritionals, they think they have found that better way: Core MRP. Core MRP is not only designed with optimal nutrients (macro and micro) in mind, but perhaps more importantly, it’s designed to fit in your life, not run it. Cores' high quality, grain-sourced carbohydrates, multiple (and rich) protein sources, premium flavors, and a plethora of extras all come in a gourmet-tasting, instantized powder – giving you the freedom to plan your favorite activities, and your diet, together.\u003c\/p\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003eCore MRP Packs Highlights\u003c\/h3\u003e\n\u003cul class=\"ticks\" data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e2 scoop serving per pack.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e10 packets per box.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eComprehensive meal formula.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cmeta charset=\"utf-8\"\u003e","brand":"Core Nutritionals","offers":[{"title":"1 Packet \/ Blueberry Crumb Cake","offer_id":45177088114930,"sku":"mrppackscore-1","price":3.99,"currency_code":"USD","in_stock":false},{"title":"1 Packet \/ Double Chocolate Oatmeal Cookie","offer_id":45177088147698,"sku":"mrppackscore-2","price":3.99,"currency_code":"USD","in_stock":false},{"title":"1 Packet \/ Peanut Butter Oatmeal Cookie","offer_id":45177088180466,"sku":"mrppackscore-3","price":3.99,"currency_code":"USD","in_stock":false},{"title":"1 Packet \/ Vanilla Poundcake","offer_id":45177088213234,"sku":"mrppackscore-4","price":3.99,"currency_code":"USD","in_stock":false},{"title":"1 Case (10 Packets) \/ Blueberry Crumb Cake","offer_id":45177088246002,"sku":"mrppackscore-5","price":39.99,"currency_code":"USD","in_stock":false},{"title":"1 Case (10 Packets) \/ Double Chocolate Oatmeal Cookie","offer_id":45177088278770,"sku":"mrppackscore-6","price":39.99,"currency_code":"USD","in_stock":false},{"title":"1 Case (10 Packets) \/ Peanut Butter Oatmeal Cookie","offer_id":45177088311538,"sku":"mrppackscore-7","price":39.99,"currency_code":"USD","in_stock":false},{"title":"1 Case (10 Packets) \/ Vanilla Poundcake","offer_id":45177088344306,"sku":"mrppackscore-8","price":39.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/mrp-blueberry_1800x1800_c64fb3d6-4acf-42fd-a0d4-256a5cb7e7d7.jpg?v=1707029559"},{"product_id":"ascension-pre-workout","title":"Ascension Pre Workout","description":"\u003ch2 style=\"text-align: center;\"\u003eAscension Pre Workout\u003c\/h2\u003e\n\u003cp\u003eAscension Pre Workout by Core Nutritionals is their most loaded, elite daily driver to date. Armed with a deep understanding of the nuances that contribute to a successful workout, Core set out to create the ultimate pre workout experience. ASCENSION is just that! This pre workout checks all the boxes when it comes to pump, power, endurance, hydration, focus, and energy. This pre workout is Doug Millers (Cores' Owner) signature pre workout. This is Dougs personal message to the world on his pre workout:\u003c\/p\u003e\n\u003cp\u003e\"Over the last 25+ years, I has produced, tested, and tried some of the most well-known and effective preworkout supplements. Being a world champion natural bodybuilder and entrepreneur in the supplement industry, I have\u003cspan\u003e \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eworked\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003etirelessly on revolutionizing the industry. Also, as a scientist and consumer, I have been committed to making sure Core Nutritionals\u003cspan data-mce-fragment=\"1\"\u003e®\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eonly formulates high-end, efficaciously dosed products for almost 20 years! Our CRUSH IT\u003cspan data-mce-fragment=\"1\"\u003e®\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eLifestyle demands this!\"\u003c\/p\u003e\n\u003ch3 style=\"text-align: left;\"\u003eAscension Pre Workout Highlights\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eCores' Most Loaded Pre Workout\u003c\/li\u003e\n\u003cli\u003eElite Daily Driver Pre Workout\u003c\/li\u003e\n\u003cli\u003e5g Creatine Monohydrate\u003c\/li\u003e\n\u003cli\u003e401mg Active Caffeine from 2 Sources\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"text-align: left;\"\u003eAscension Pre Workout Ingredients\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eL-Citrulline\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCitrulline is a non-essential, non-protein amino acid that forms during the urea cycle and forms ornithine when combined with carbon dioxide. Citrulline is also a critical source of endogenous (natural) arginine, as it is rapidly and efficiently converted to arginine in the vascular endothelium and other tissues.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBeta Alanine\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCarnosine, a critical compound for muscle function, has long intrigued researchers due to its essential role in buffering pH levels in muscle cells, particularly during intense exercise. However, efforts to increase intramuscular carnosine levels via direct supplementation faced challenges due to rapid degradation in the body. The introduction of beta-alanine, a precursor to carnosine, revolutionized this approach. Beta-alanine has proven to be highly effective in significantly increasing intramuscular carnosine concentrations, thereby unlocking carnosine's beneficial effects on muscle performance. Moreover, beta-alanine itself exhibits physiological benefits beyond its role as a carnosine precursor. By synthesizing carnosine from the precursors L-histidine and l-alanine, carnosine acts as a chemical buffer in muscle cells, crucial for sustained performance during intense exercise.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCreatine Monohydrate\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCreatine, often hailed as the \"grandfather\" of dietary supplements, stands alongside caffeine as one of the most extensively researched compounds in the field. Renowned as the premier ergogenic aid, the wealth of data on creatine illustrates its multifaceted benefits. Primarily, it promotes vasodilation, facilitates nutrient mobilization, enhances nitrogen retention, and augments protein synthesis post-workout. Its prowess lies in its ability to dose-dependently elevate contractile force through ATP provision, essentially bolstering strength.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eArginine Nitrate (as NO3-T®)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNitric oxide (NO) is involved in many vascular and cellular functions as a signaling molecule for cellular respiration, vasodilation, and angiogenesis. NO is produced through both endogenous and exogenous pathways through dietary nitrate ingestion. Nitrates are converted to nitrite, which is then converted to nitric oxide. Found naturally in many foods such as leafy greens and beets, NO has a long history of scientific literature to back its potential effects as an ergogenic aid and other health-promoting effects.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eHydroprime® (65% Glycerol Powder)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eGlycerol is a fascinating and highly useful compound that has achieved a somewhat cult status in the fitness community – while both peer-reviewed research and anecdotal reports centered on the endurance functions of glycerol are plentiful, its bodybuilding applications are not as widely lauded. Those who do use glycerol, however, are persistent in their belief that it provides some of the most noticeable, and effective, engorging (“pump”) effects possible.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eL-Tyrosine\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTyrosine is amongst a class of amino acids known as ‘non-essential’ amino acids, so called because the body can produce them endogenously, and it is therefore not essential to consume dietary tyrosine. That said, tyrosine is also what is known as a conditionally essential amino acid; conditionally essential because, along with glucose and ammonia, the synthesis of tyrosine additionally requires adequate levels of phenylalanine. Once synthesized, tyrosine is one of the most critical amino acids, given its prominent role as a substrate in the synthesis of the catecholamines dopamine, norepinephrine, and epinephrine, in addition to both T3 (triiodothyronine) and T4 (thyroxine) thyroid hormones.\u003c\/p\u003e\n\u003cp\u003eIn studies on stress modulation, tyrosine has been demonstrated to reverse stress-induced norepinephrine depletion and the depressant-behavioral effects normally associated with it. In simpler terms, tyrosine may, in certain conditions, dampen the extent to which norepinephrine is removed from the bloodstream during a stress event. In simpler terms still, tyrosine may help to mitigate the sense of depletion and fatigue felt at the end of a workout.\u003c\/p\u003e\n\u003cp\u003eTyrosine may also play important metabolic functions, mostly related to its role in synthesizing compounds which stimulate the nervous system. While not traditionally considered a sympathomimetic amine, studies which have coadministered tyrosine and stimulants demonstrate a synergistic effect. These studies suggest that tyrosine may potentiate the effects of both endogenous and supplemental norepinephrine and its mimetics (in the case of exogenous use) with respect to lipolysis, thermogenesis, and energy expenditure. Meaning that tyrosine may play a role in assisting norepinephrine to break up triglycerides and increase body heat transiently.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eL-Taurine\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTraditionally referred to as an amino acid due to its chemical structure, taurine is not an amino acid in the sense that leucine, alanine, or glutamine are. Its chemical status aside, taurine is considered one of the body’s most essential chemical compounds, as cardiovascular function, muscle development and function, along with optical and nervous systems in the body depend on its abundance. While data on taurine typically occurs with taurine in supplement combinations (with caffeine and other amino acids), these data nevertheless suggest that dietary supplementation with taurine may have beneficial effects on mental focus and alertness and may assist during times of increased physical exertion.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eAlpha-GPC 50%\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAmong the various choline pro-drugs or precursors, Alpha GPC stands out for its significant impact on circulating choline levels. Choline, an essential nutrient, plays a crucial role in numerous metabolic pathways, including DNA regulation, protein function, and metabolism. Notably, choline serves as a precursor for the synthesis of acetylcholine, a critical neurotransmitter involved in various physiological functions, such as muscular contraction and cognitive processes like memory and learning. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eVasoDrive-AP®\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVasodrive-AP® is a patented dietary supplement ingredient composed of a precise blend of naturally derived peptides, primarily derived from casein hydrolysate. This ingredient has garnered attention for its potential benefits in enhancing exercise performance through its vasodilatory properties. Vasodrive-AP® works by promoting the release of nitric oxide (NO), a key signaling molecule involved in vasodilation, which leads to the relaxation of blood vessels and increased blood flow to exercising muscles. It does this through several mechanisms of action. First, the increase in the production of endothelial nitric oxide synthase (eNOS) improves arterial flexibility leading to enhanced blood flow.\u003c\/p\u003e\n\u003cp\u003eSecond, Vasodrive-AP® can also inhibit the enzyme that leads to the constriction of blood vessels. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCaffeine Anhydrous\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCaffeine is one of the most widely consumed, and perhaps one of the most reviewed, psychoactive compounds. Its physiological effects in a range of areas have been well-documented, including exercise performance, information processing, alertness and mood enhancement, attention, and awareness, along with its anti-lipogenic and lipolytic abilities.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eZüm-XR® (yields 70% caffeine)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eZüm-XR is a patented coating technology that allows the dissolution profile of certain ingredients, primarily caffeine, to have a longer lasting effect in blood serum levels. The release of those ingredients is initiated by an abrasion in the stomach and pH levels between the stomach and the upper gastrointestinal tract. The coating of the microbead technology is a patented timing system with pharmaceutical grade safe polymers. Comparatively speaking, the dissolution profile of Züm-XR caffeine to your typical immediate release caffeine showed that Züm-XR took a far greater amount of time, well over 120 minutes to complete the process of dissolution.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBitter Orange Extract (Citrus aurantium) (30% synephrine)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBitter orange extract, derived from the fruit of Citrus aurantium, contains a diverse array of bioactive compounds, notably including synephrine, flavonoids, and essential oils. Synephrine, the principal alkaloid in bitter orange extract, exhibits sympathomimetic properties, stimulating the sympathetic nervous system and potentially increasing heart rate, blood pressure, and metabolic rate. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCognatiQ® (Coffea arabica) (Whole Coffee Fruit Extract)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCognatiQ®, an extract derived from the whole fruit Coffea arabica plant, is a clinically proven ingredient shown to stimulate the production of the neuroprotein, Brain-Derived Neurotrophic Factor (BDNF). BDNF has been shown to be crucial in the development, maintenance and repair of neurons and also protect against neurodegeneration. One study comparing other coffee, caffeine, and polyphenol compounds, showed that they were not statistically significant in increasing BDNF % compared to CognatiQ®. The unique polyphenol profile found in CognatiQ® showed to be superior in increasing BDNF concentration.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eHuperzia serrata Extract (Leaf and Stem) (1% Huperzine A)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eHuperzia serrata, a compound found in plant families such as Huperziaceae, Lycopodiaceae, and Selaginella, is native to China. The Lycopodium alkaloid Huperzine-A, present in Core Ascension, was initially extracted from a traditional medicinal preparation in 1984.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003ePregnenolone\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePregnenolone, or pregn-5-en-3β-ol-20-one, is known as the grandmother hormone due to its precursor role in the endogenous biosynthesis of most steroid hormones. Pregnenolone also has potent intrinsic activity, however, functioning as a neurosteroid. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eRauwolscine (Rauwolfia vomitoria Root Extract) (std. min 90% Alpha Yohimbine)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAlpha Yohimbine, also known as rauwolscine, offers several potential benefits, particularly in the realm of sports performance as well as weight management. As a dietary supplement, it is often touted for its ability to enhance fat loss and promote energy expenditure, making it popular amongst many athletes. Alpha Yohimbine exhibits a mechanism of action that works to antagonize alpha-2 adrenergic receptors, which can lead to increased lipolysis, which is the breakdown of stored fatty acids that can then be used as a fuel source for the body. \u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"40\/20 Serving \/ Lion On The Beach","offer_id":45306882031858,"sku":"coreascensionpreworkout","price":74.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/ascensionpre.jpg?v=1709497686"},{"product_id":"allspark-hydration-eaa","title":"AllSpark Hydration + EAA","description":"\u003ch2 style=\"text-align: center;\"\u003eAllSpark Hydration + EAA\u003c\/h2\u003e\n\u003cp\u003eAllSpark is an epic hydration+EAA supplement collab between Core Nutritionals and the Transformers. Not only is this a super epic collab, this is also a well dosed hydration and Essential Amino Acid formula.\u003c\/p\u003e\n\u003cp\u003eOn top of these awesome factors, each bottle of AllSpark comes with a Transformer toy!\u003c\/p\u003e\n\u003ch3\u003e\n\u003cmeta charset=\"utf-8\"\u003eAllSpark Hydration + EAA Highlights\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e30 Servings\u003c\/li\u003e\n\u003cli\u003eSolid Hydration + EAA formula\u003c\/li\u003e\n\u003cli\u003eEpic Core x Transformers Collab\u003c\/li\u003e\n\u003cli\u003eMay Aid with Hydration\u003c\/li\u003e\n\u003cli\u003eMay Aid with Athletic Performance and Recovery\u003c\/li\u003e\n\u003cli\u003eEach Unit Comes with A Mystery Toy!\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\n\u003cmeta charset=\"utf-8\"\u003eAllSpark Hydration + EAA Supplement Facts\u003c\/h3\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg style=\"float: none; display: block; margin-left: auto; margin-right: auto;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/allsparksupplementfacts_480x480.jpg?v=1726847121\"\u003e\u003c\/div\u003e\n\u003ch3\u003e\n\u003cmeta charset=\"utf-8\"\u003eAllSpark Hydration + EAA Other Ingredients\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eMegatron (Blood Orange Passion Fruit)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCitric Acid, Natural Flavors, Silicon Dioxide, Sucralose, Beet Root Powder (for color), Beta Carotene (for color).\u003c\/p\u003e\n\u003cp\u003eCONTAINS: Tree Nut (coconut)\u003c\/p\u003e\n\u003ch3\u003e\n\u003cmeta charset=\"utf-8\"\u003eAllSpark Hydration + EAA Suggested Use\u003c\/h3\u003e\n\u003cp\u003eMix 1 scoop with 10-14 ounces of water and consume before and\/or during training. Additional servings can be taken throughout the day.\u003c\/p\u003e\n\u003ch3\u003e\n\u003cmeta charset=\"utf-8\"\u003eAllSpark Hydration + EAA Other Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Disclaimers in \u003cmeta charset=\"utf-8\"\u003eAllSpark?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\" dir=\"ltr\"\u003e\u003cspan\u003eYes, (California Residents) Prop 65 applies in this product. Consuming this supplement can expose you to chemicals including lead which is known in the state of California to cause cancer and birth defects or other reproductive harm. For more information, please visit www.p65warnings.ca.gov\/food.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\" dir=\"ltr\"\u003e\u003cspan\u003eAny statements made on this product page or on the product itself have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Allergens In \u003cmeta charset=\"utf-8\"\u003eAllSpark?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\" dir=\"ltr\"\u003e\u003cstrong\u003eThis product claims tree nuts (coconut) is present in all flavors.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eAlso\u003cspan data-mce-fragment=\"1\"\u003e, this product is manufactured in a facility that processes all of the major allergens (milk, eggs, shellfish, tree nuts, peanuts, wheat, soybeans, sesame)\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eWhat Are The Warnings Associated With \u003cmeta charset=\"utf-8\"\u003eAllSpark?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNot intended for individuals under 18 years of age. Pregnant or nursing women should not use this product. Consult with a healthcare professional prior to use, especially if you have a medical condition or are taking any prescription or over the counter medication. Discontinue use and consult your healthcare professional if you experience any adverse reaction to this product. Do not exceed recommended serving size. Do not use if safety seal is broken or missing. Keep out of reach of children.\u003c\/p\u003e\n\u003cp\u003eDo not take with other stimulants or alcohol. Ensure you properly hydrate before taking and after taking this product. \u003cspan\u003eDo not exceed recommended dosage. \u003c\/span\u003eDiscontinue use 2 weeks prior to surgery.\u003c\/p\u003e\n\u003cp\u003eStore in cool conditions (59-86 degrees F) in a dry area away from moisture and from sunlight exposure. Product does not completely fill container. This product contains the servings indicated when measured exactly by weight. Settling occurs in shipping. \u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"30 Servings \/ Starscream (Grape Lemonade)","offer_id":48024285839602,"sku":"allspark-4","price":44.99,"currency_code":"USD","in_stock":true},{"title":"30 Servings \/ Bumblebee (Sour Lemon Candy)","offer_id":46861018530034,"sku":"allspark-1","price":44.99,"currency_code":"USD","in_stock":false},{"title":"30 Servings \/ Megatron (Blood Orange Passion Fruit)","offer_id":46861018562802,"sku":"allspark-2","price":44.99,"currency_code":"USD","in_stock":false},{"title":"30 Servings \/ Optimus Prime (Mixed Berry Kiwi)","offer_id":46861018595570,"sku":"allspark-3","price":44.99,"currency_code":"USD","in_stock":false},{"title":"30 Servings \/ Bumblebee (Sour Lemon Candy) (Best by 8\/26)","offer_id":49991904690418,"sku":null,"price":31.49,"currency_code":"USD","in_stock":true},{"title":"30 Servings \/ Optimus Prime (Mixed Berry Kiwi) (Best by 8\/26)","offer_id":49991905706226,"sku":null,"price":31.49,"currency_code":"USD","in_stock":true},{"title":"30 Servings \/ Megatron (Blood Orange Passion Fruit) (Best by 8\/26)","offer_id":49991907868914,"sku":null,"price":31.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/ALLSPARK_GRAPELEMONADE_FRONT_Large_a5e265b9-f45a-46ed-8506-6289759a6f4a.jpg?v=1759771833"},{"product_id":"energon-pre-workout","title":"Energon Pre Workout","description":"\u003ch2 style=\"text-align: center;\"\u003eEnergon Pre Workout\u003c\/h2\u003e\n\u003cp\u003eEnergon Pre Workout is an epic and higher end daily driver pre workout collab between Core Nutritionals and the Transformers. Not only is this a super epic collab, this is also a well dosed pre workout and may provide great pumps, energy and focus. Energon replaces caffeine with Enfinity, which claims to have all of the benefits of caffeine without the jitters.\u003c\/p\u003e\n\u003cp\u003eOn top of these awesome factors, each bottle of AllSpark comes with a Transformer toy!\u003c\/p\u003e\n\u003ch3\u003eEnergon Pre Workout Highlights\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e20 Servings\u003c\/li\u003e\n\u003cli\u003eDaily Driver Pre Workout\u003c\/li\u003e\n\u003cli\u003eEpic Core x Transformers Collab\u003c\/li\u003e\n\u003cli\u003eMay Aid with Pumps\u003c\/li\u003e\n\u003cli\u003eMay Aid with Athletic Performance and Energy\u003c\/li\u003e\n\u003cli\u003eEach Unit Comes with A Mystery Toy!\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eEnergon Pre Workout Supplement Facts\u003c\/h3\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/energonsupplementfacts_480x480.jpg?v=1726848124\" alt=\"\" style=\"float: none; display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/div\u003e\n\u003ch3\u003eEnergon Pre Workout Other Ingredients\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eOptimus Prime (Mixed Berry Kiwi)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSilicon Dioxide, Citric Acid, Natural Flavors, Sucralose, Beet Root Powder (for color).\u003c\/p\u003e\n\u003cp\u003eCONTAINS: Milk.\u003c\/p\u003e\n\u003ch3\u003eEnergon Pre Workout Suggested Use\u003c\/h3\u003e\n\u003cp\u003eMix 1 scoop with 10-14 ounces of water and consume approximately 15-30 minutes before training. To assess tolerance, users may want to start with 1\/2 scoop.\u003c\/p\u003e\n\u003ch3\u003eEnergon Pre Workout Other Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Disclaimers in \u003cmeta charset=\"utf-8\"\u003eEnergon?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cspan\u003eYes, (California Residents) Prop 65 applies in this product. Consuming this supplement can expose you to chemicals including lead which is known in the state of California to cause cancer and birth defects or other reproductive harm. For more information, please visit www.p65warnings.ca.gov\/food.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cspan\u003eAny statements made on this product page or on the product itself have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Allergens In \u003cmeta charset=\"utf-8\"\u003eEnergon?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cstrong\u003eThis product claims Milk is present in all flavors.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eAlso\u003cspan data-mce-fragment=\"1\"\u003e, this product is manufactured in a facility that processes all of the major allergens (milk, eggs, shellfish, tree nuts, peanuts, wheat, soybeans, sesame)\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eWhat Are The Warnings Associated With \u003cmeta charset=\"utf-8\"\u003eEnergon?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNot intended for individuals under 18 years of age. Pregnant or nursing women should not use this product. Consult with a healthcare professional prior to use, especially if you have a medical condition or are taking any prescription or over the counter medication. Discontinue use and consult your healthcare professional if you experience any adverse reaction to this product. Do not exceed recommended serving size. Do not use if safety seal is broken or missing. Keep out of reach of children.\u003c\/p\u003e\n\u003cp\u003eDo not take with other stimulants or alcohol. Ensure you properly hydrate before taking and after taking this product. \u003cspan\u003eDo not exceed recommended dosage. \u003c\/span\u003eDiscontinue use 2 weeks prior to surgery.\u003c\/p\u003e\n\u003cp\u003eStore in cool conditions (59-86 degrees F) in a dry area away from moisture and from sunlight exposure. Product does not completely fill container. This product contains the servings indicated when measured exactly by weight. Settling occurs in shipping. \u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"20 Servings \/ Starscream (Grape Lemonade)","offer_id":48024285806834,"sku":"energonpre-4","price":54.99,"currency_code":"USD","in_stock":false},{"title":"20 Servings \/ Optimus Prime (Mixed Berry Kiwi)","offer_id":46861768589554,"sku":"energonpre-1","price":54.99,"currency_code":"USD","in_stock":true},{"title":"20 Servings \/ Bumblebee (Sour Lemon Candy)","offer_id":46861768622322,"sku":"energonpre-2","price":54.99,"currency_code":"USD","in_stock":true},{"title":"20 Servings \/ Megatron (Blood Orange Passion Fruit)","offer_id":46861768655090,"sku":"energonpre-3","price":54.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/ENERGON_GRAPELEMONADE_FRONT_1_Large_b3a07eca-af3c-46bf-b510-0610312132a2.jpg?v=1759771761"},{"product_id":"protron-whey-protein","title":"Protron Whey Protein","description":"\u003ch2 style=\"text-align: center;\"\u003eProtron Whey Protein Blend\u003c\/h2\u003e\n\u003cp\u003eProtron is a whey protein blend of whey protein isolate, milk protein isolate and whey protein concentrate, yielding 25 grams of protein per serving. Not only is this a super epic collab, but these flavors are legit and insane. \u003c\/p\u003e\n\u003cp\u003eOn top of these awesome factors, each bottle of Protron comes with a Transformer toy!\u003c\/p\u003e\n\u003ch3\u003eProtron Whey Protein Highlights\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eDelicious Flavors\u003c\/li\u003e\n\u003cli\u003eWhey Protein Isolate + Concentrate Blend\u003c\/li\u003e\n\u003cli\u003eEpic Core x Transformers Collab\u003c\/li\u003e\n\u003cli\u003e25 Grams of Protein Per Servings\u003c\/li\u003e\n\u003cli\u003eMay Aid with Athletic Performance and Recovery\u003c\/li\u003e\n\u003cli\u003eEach Unit Comes with A Mystery Toy!\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProtron Whey Protein Supplement Facts\u003c\/h3\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg style=\"margin-right: auto; float: none; display: block; margin-left: auto;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/protronsuppfacts_480x480.jpg?v=1726848799\"\u003e\u003c\/div\u003e\n\u003ch3\u003eProtron Whey Protein Other Ingredients\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eBumblebee (Vanilla Honey Graham)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhey Protein Concentrate (15.63g yielding 12.5g), Whey Protein Isolate (6.94g yielding 6.25g), Milk Protein Isolate (6.94g yielding 6.25g), Coconut Oil Creamer, Natural \u0026amp; Artificial Flavors, Sunflower Lecithin, Gum Blend (Cellulose Gum, Gum Acacia, Xanthan Gum, Guar Gum, Carrageenan), Sucralose, Sodium Chloride, DigeSEBR (Amylases,\u003cbr\u003eLactase, Proteases, Lipase, Cellulase).\u003c\/p\u003e\n\u003cp\u003eCONTAINS: Milk, Tree Nut (coconut)\u003c\/p\u003e\n\u003ch3\u003eProtron Whey Protein Suggested Use\u003c\/h3\u003e\n\u003cp\u003eAdd 1 scoop to 6-8 ounces of cold water and shake or stir until mixed.\u003c\/p\u003e\n\u003ch3\u003eProtron Whey Protein Other Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Disclaimers in \u003cmeta charset=\"utf-8\"\u003eProtron?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\" dir=\"ltr\"\u003e\u003cspan\u003eYes, (California Residents) Prop 65 applies in this product. Consuming this supplement can expose you to chemicals including lead which is known in the state of California to cause cancer and birth defects or other reproductive harm. For more information, please visit www.p65warnings.ca.gov\/food.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\" dir=\"ltr\"\u003e\u003cspan\u003eAny statements made on this product page or on the product itself have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Allergens In \u003cmeta charset=\"utf-8\"\u003eProtron?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\" dir=\"ltr\"\u003e\u003cstrong\u003eThis product claims Milk and Tree Nuts (Coconut) are present in all flavors.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eAlso\u003cspan data-mce-fragment=\"1\"\u003e, this product is manufactured in a facility that processes all of the major allergens (milk, eggs, shellfish, tree nuts, peanuts, wheat, soybeans, sesame)\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eWhat Are The Warnings Associated With \u003cmeta charset=\"utf-8\"\u003eProtron?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNot intended for individuals under 18 years of age. Pregnant or nursing women should not use this product. Consult with a healthcare professional prior to use, especially if you have a medical condition or are taking any prescription or over the counter medication. Discontinue use and consult your healthcare professional if you experience any adverse reaction to this product. Do not exceed recommended serving size. Do not use if safety seal is broken or missing. Keep out of reach of children.\u003c\/p\u003e\n\u003cp\u003eDo not take with other stimulants or alcohol. Ensure you properly hydrate before taking and after taking this product. \u003cspan\u003eDo not exceed recommended dosage. \u003c\/span\u003eDiscontinue use 2 weeks prior to surgery.\u003c\/p\u003e\n\u003cp\u003eStore in cool conditions (59-86 degrees F) in a dry area away from moisture and from sunlight exposure. Product does not completely fill container. This product contains the servings indicated when measured exactly by weight. Settling occurs in shipping. \u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"2 lbs (About 27 Servings) \/ Starscream (Milk Chocolate Cookies n' Cream)","offer_id":48024285380850,"sku":"protron-strscrm","price":49.99,"currency_code":"USD","in_stock":false},{"title":"2 lbs (About 27 Servings) \/ Bumblebee (Vanilla Honey Graham)","offer_id":46861799063794,"sku":"protron-bumbee","price":49.99,"currency_code":"USD","in_stock":true},{"title":"2 lbs (About 27 Servings) \/ Optimus Prime (Mixed Berry CheeseCake)","offer_id":46861799096562,"sku":"protron-optprm","price":49.99,"currency_code":"USD","in_stock":true},{"title":"2 lbs (About 27 Servings) \/ Megatron (Peanut Butter Cookies 'N Cream)","offer_id":46861799129330,"sku":"protron-mgtrn","price":49.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/PROTRON_MILKCHOCOLATE_FRONT_Large_1599c1ec-4ce1-4b7e-adb6-22ad3ec5e523.jpg?v=1759771732"},{"product_id":"core-kidney","title":"Core Kidney","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Kidney\u003c\/h2\u003e\n\u003cp\u003eCore Kidney is a supplement that aims to support healthy kidney functions, bladder health and overall kidney health. Core Kidney includes a unique blend of multiple ingredients to achieve this support.\u003c\/p\u003e\n\u003cp\u003eGo-Less®\u003cspan\u003e \u003c\/span\u003eis a blend of pumpkin seed and soy germ extracts designed to support kidney and bladder health. It promotes bladder strength and flexibility, reduces urgency, and improves overall bladder function, making it especially beneficial for individuals with overactive bladder (OAB) symptoms. Clinical studies have shown that Go-Less® helps reduce urinary frequency and urgency, leading to improved bladder control and sleep quality. The supplement also supports kidney health by aiding in detoxification and helping the kidneys efficiently filter waste and excess fluids, lowering the risk of kidney-related issues.\u003c\/p\u003e\n\u003cp\u003eGoldenrod extract, a versatile herb, is known for its diuretic, anti-inflammatory, and antimicrobial properties, which help maintain a healthy urinary system and manage conditions like UTIs and kidney stones. PaCran® cranberry extract, rich in flavonoids, provides protection against UTIs by preventing the adhesion of pathogens to the urinary tract, and also reduces inflammation and supports bladder function. Other ingredients like Stinging Nettle, Grape Seed, and Astragalus extracts further support kidney and bladder health by promoting healthy urine flow, reducing oxidative stress, and enhancing immune function, making this supplement an effective, natural solution for maintaining urinary health.\u003c\/p\u003e\n\u003ch3\u003eCore Kidney Highlights\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e30 Servings\u003c\/li\u003e\n\u003cli\u003eFull Spectrum Kidney Support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Kidney Supplement Facts\u003c\/h3\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg style=\"float: none; display: block; margin-left: auto; margin-right: auto;\" alt=\"Core Kidney Supplement Facts Panel\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/Core-Kidney-Supplement-Facts-Panel_480x480.jpg?v=1739656569\"\u003e\u003c\/div\u003e\n\u003cul\u003e\n\u003cli\u003eGo-Less® Proprietary Blend [Pumpkin (\u003ci\u003eCurcurbita pepo\u003c\/i\u003e) Seed Extract, Soy (Glycine max) Germ Extract]\u003c\/li\u003e\n\u003cli\u003eGoldenrod Extract 10:1 (\u003ci\u003eSolidago decurrens Lour\u003c\/i\u003e) (Whole Plant)\u003c\/li\u003e\n\u003cli\u003ePaCran® Cranberry Extract\u003c\/li\u003e\n\u003cli\u003eStinging Nettle Extract (\u003ci\u003eUrtica dioica\u003c\/i\u003e) (Root) (20:1)\u003c\/li\u003e\n\u003cli\u003eGrape Seed Extract (\u003ci\u003eVitis vinifera\u003c\/i\u003e) (Seed) (Std. to 95% Proanthocyanidins)\u003c\/li\u003e\n\u003cli\u003eAstragalus Extract (\u003ci\u003eAstragalus membranaceous\u003c\/i\u003e) (Root) (Std. to 50% Polysaccharides)\u003c\/li\u003e\n\u003cli\u003eSetria® Glutathione\u003c\/li\u003e\n\u003cli\u003eAstraGin® (\u003ci\u003eAstragalus membranaceus\u003c\/i\u003e and \u003ci\u003ePanax notoginseng\u003c\/i\u003e Root Extracts)\u003c\/li\u003e\n\u003cli\u003eBioPerine® (\u003ci\u003ePiper nigrum\u003c\/i\u003e) (Fruit) (Std. to 95% piperine)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Kidney Suggested Use\u003c\/h3\u003e\n\u003cp\u003eTake 4 capsules daily with or without food.\u003c\/p\u003e\n\u003ch3\u003eCore Kidney Other Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Disclaimers in Core Kidney?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cspan\u003eYes, (California Residents) Prop 65 applies in this product. Consuming this supplement can expose you to chemicals including lead which is known in the state of California to cause cancer and birth defects or other reproductive harm. For more information, please visit www.p65warnings.ca.gov\/food.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cspan\u003eAny statements made on this product page or on the product itself have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eAre There Any Allergens In Core Kidney?\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cstrong\u003eThis product claims none of the major allergens are present.\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003eHowever\u003cspan\u003e, this product is manufactured in a facility that processes all of the major allergens (milk, eggs, shellfish, tree nuts, peanuts, wheat, soybeans, sesame)\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eWhats The Warning Statement On Core Kidney?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis product is only intended for use in healthy adults 18 years of age or older. Pregnant or nursing women should not use this product. Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication. Discontinue use and consult your health care professional if you experience adverse reaction to this product. Discontinue use 2 weeks prior to surgery. Do not exceed recommended serving. Do not use if safety seal is broken or missing. Keep out of reach of children.\u003c\/p\u003e\n\u003cp\u003eStore in cool conditions (59-86 degrees F) in a dry area away from moisture and from sunlight exposure. Product may not completely fill container. Do not use if safety seal is broken or missing.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":47298180055282,"sku":"corekidney","price":54.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/Core-Kidney.jpg?v=1739656569"},{"product_id":"core-nutritionals-flavored-creatine","title":"Core Nutritionals Flavored Creatine","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Nutritionals Flavored Creatine\u003c\/h2\u003e\n\u003cdiv class=\"product-template__container style1 page-width\" data-style=\"style1\" id=\"ProductSection-product-template\" data-section-id=\"product-template\" data-section-type=\"product\" data-enable-history-state=\"true\"\u003e\n\u003cdiv class=\"tabs-listing wow fadeIn\"\u003e\n\u003cdiv class=\"tab-container\"\u003e\n\u003cdiv id=\"tab2\" class=\"tab-content\"\u003e\n\u003cp\u003eCore Nutritionals has done it again with their Fun Sweets® Cotton Candy collab flavors! Now with creatine.\u003c\/p\u003e\n\u003cp\u003eCreatine is perhaps the most studied and verified of all dietary supplements, earning its moniker as the, “grandfather of supplements.” Through a number of enzymatic and cellular steps, creatine is first metabolized into a compound known as phosophocreatine, and eventually into a compound known as ATP (adenosine triphosphate) – the so-called, “energy currency” of the human body.\u003c\/p\u003e\n\u003cp\u003eAs a dietary supplement, the use of creatine over extended periods of time has been linked to a wide-range of physiological benefits, including: cell volumization, increased delivery of plasma (blood) nutrients to the cell, an increase in skeletal muscle total mass and protein synthesis, decrease in muscular fatigue, and increased endurance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch3\u003eCore Flavored Creatine Highlights\u003c\/h3\u003e\n\u003cul class=\"ticks\"\u003e\n\u003cli\u003eMay help increase muscle mass\/size.\u003c\/li\u003e\n\u003cli\u003eMay help improve strength, power, and performance.\u003c\/li\u003e\n\u003cli\u003eMay decrease muscular fatigue in response to high intensity exercise.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Flavored Creatine Supplement Facts\u003c\/h3\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/flavoredcreatinecore_480x480.jpg?v=1744351434\" alt=\"\" style=\"float: none; display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/div\u003e\n\u003ch3\u003eCore Flavored Creatine Suggested Use\u003c\/h3\u003e\n\u003cp\u003eMix 1 scoop (1 serving) with 8 ounces of water and consume once daily. Read entire label before use and follow directions provided.\u003c\/p\u003e\n\u003ch3\u003eCore Flavored Creatine Other Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Disclaimers in \u003cmeta charset=\"utf-8\"\u003eCore Flavored Creatine?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cspan\u003eYes, (California Residents) Prop 65 applies in this product. Consuming this supplement can expose you to chemicals including lead which is known in the state of California to cause cancer and birth defects or other reproductive harm. For more information, please visit www.p65warnings.ca.gov\/food.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cspan\u003eAny statements made on this product page or on the product itself have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Allergens In \u003cmeta charset=\"utf-8\"\u003eCore Flavored Creatine?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cstrong\u003eThis product claims none of the major allergens are present.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eHowever\u003cspan\u003e, this product is manufactured in a facility that processes all of the major allergens (milk, eggs, shellfish, tree nuts, peanuts, wheat, soybeans, sesame)\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eWhats The Warnings Associated With Core Flavored Creatine?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eKEEP OUT OF THE REACH OF CHILDREN. Do not take this product if pregnant or breastfeeding. Only for use by individuals 18 years of age of older. Do not take this product before consulting a licensed, qualified health care professional if you are taking any other dietary supplement, prescription drug, over-the-counter medication; or if, you suspect you have treated for, diagnosed with or have a family history of any medical condition. Do not exceed recommended dosage or take with other stimulants or alcohol. Ensure you are properly hydrated before and after taking this product and during exercise. Do not take if dehydrated or in conditions of excessive heat. Discontinue 2 weeks prior to surgery. Immediately discontinue use and contact a medical doctor if you experience any adverse reaction to this product. Do not use if safety seal is broken or missing. Store in a cool and dry place.\u003cbr\u003eThis product is sold by weight, not volume. Some settling of powder may occur during shipping and handling, which may affect density of powder. This product contains the servings indicated when measured exactly by weight.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"50 Serving \/ Orange Creamsicle","offer_id":47463185481970,"sku":"coreflavoredcreatine-orngcrm","price":24.99,"currency_code":"USD","in_stock":true},{"title":"50 Serving \/ Blue Raspberry","offer_id":47463185514738,"sku":"coreflavoredcreatine-blurasp","price":24.99,"currency_code":"USD","in_stock":true},{"title":"50 Serving \/ Cherry Berry","offer_id":47463185547506,"sku":"coreflavoredcreatine-chrybry","price":24.99,"currency_code":"USD","in_stock":false},{"title":"50 Serving \/ Lemon Lime","offer_id":47463185842418,"sku":"coreflavoredcreatine-lemlim","price":24.99,"currency_code":"USD","in_stock":true},{"title":"50 Serving \/ Fruit Punch","offer_id":47463185940722,"sku":"coreflavoredcreatine-frtpnch","price":24.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/CreatineOrangeCreamFront_1800x1800_99300749-0940-45d6-8b18-c1cb56dabe59.jpg?v=1744351449"},{"product_id":"core-essential-pre-workout","title":"Core Essential Pre Workout","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Essential Pre Workout\u003c\/h2\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCore Essential Pre Workout is an essential pre-workout designed to fuel your training day in and day out with solid dosed ingredients to support energy, endurance, and focus. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWith 200mg of caffeine, it delivers a clean, steady boost of energy making it ideal for daily use. With other ingredients like L-Citrulline to support nitric oxide production and enhanced muscle pumps, beta-alanine for delaying muscle fatigue and enhancing performance, and Alpha-GPC for a cognitive boost enhancing mind-muscle connection and workout intensity. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eCore Essential Pre Highlights\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e200mg Caffeine\u003c\/li\u003e\n\u003cli\u003e30 Servings\u003c\/li\u003e\n\u003cli\u003eCores' Essential \u0026amp; Budget Friendly Pre Workout\u003c\/li\u003e\n\u003cli\u003eAuthentic Fun Sweet (Cotton Candy) Flavors\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCore Essential Pre Supplement Facts\u003c\/h3\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/Core-Pre-FunSweets-CherryBerry-15x3-FINAL_0d135861-879b-4bb4-a345-d3a5757348c5_480x480.jpg?v=1746323564\" alt=\"\" style=\"float: none; display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/div\u003e\n\u003ch3\u003eCore Essential Pre Suggested Use\u003c\/h3\u003e\n\u003cp\u003eMix 1 scoop (1 serving) with 8-12 ounces of water and consume 20-30 minutes prior to training. Read entire label before use and follow directions provided.\u003c\/p\u003e\n\u003ch3\u003eCore Essential Pre Other Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Disclaimers in Core Essential Pre?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cspan\u003eYes, (California Residents) Prop 65 applies in this product. Consuming this supplement can expose you to chemicals including lead which is known in the state of California to cause cancer and birth defects or other reproductive harm. For more information, please visit www.p65warnings.ca.gov\/food.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cspan\u003eAny statements made on this product page or on the product itself have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Allergens In Core Essential Pre?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\" class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\"\u003e\u003cstrong\u003eThis product claims none of the major allergens are present.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eHowever\u003cspan\u003e, this product is manufactured in a facility that processes all of the major allergens (milk, eggs, shellfish, tree nuts, peanuts, wheat, soybeans, sesame)\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eWhats The Warnings Associated With Core Essential Pre?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eKEEP OUT OF THE REACH OF CHILDREN. Do not take this product if pregnant or breastfeeding. Only for use by individuals 18 years of age of older. Do not take this product before consulting a licensed, qualified health care professional if you are taking any other dietary supplement, prescription drug, over-the-counter medication; or if, you suspect you have treated for, diagnosed with or have a family history of any medical condition. Do not exceed recommended dosage or take with other stimulants or alcohol. Ensure you are properly hydrated before and after taking this product and during exercise. Do not take if dehydrated or in conditions of excessive heat. Discontinue 2 weeks prior to surgery. Immediately discontinue use and contact a medical doctor if you experience any adverse reaction to this product. Do not use if safety seal is broken or missing. Store in a cool and dry place.\u003cbr\u003eThis product is sold by weight, not volume. Some settling of powder may occur during shipping and handling, which may affect density of powder. This product contains the servings indicated when measured exactly by weight.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"30 Servings \/ Orange Cream (Fun Sweets)","offer_id":47538162860274,"sku":"corepreessential-fsorngcrm","price":34.99,"currency_code":"USD","in_stock":false},{"title":"30 Servings \/ Blue Raspberry (Fun Sweets)","offer_id":47538162893042,"sku":"corepreessential-fsblursp","price":34.99,"currency_code":"USD","in_stock":true},{"title":"30 Servings \/ Cherry Berry (Fun Sweets)","offer_id":47538162925810,"sku":"corepreessential-fschrybry","price":34.99,"currency_code":"USD","in_stock":true},{"title":"30 Servings \/ Fruit Punch","offer_id":47538162958578,"sku":"corepreessential-frtpnch","price":34.99,"currency_code":"USD","in_stock":true},{"title":"30 Servings \/ Lemon Lime","offer_id":47538162991346,"sku":"corepreessential-lemlim","price":34.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/CORE_PRE_OC_1800x1800Large.jpg?v=1746323363"},{"product_id":"core-vital-t","title":"Core Vital T","description":"\u003ch2 style=\"text-align: center;\"\u003eCore Vital T\u003c\/h2\u003e\n\u003cp\u003eVITAL-T is a test optimization supplement made by Core Nutritionals to help you feel strong and full of energy every day.\u003c\/p\u003e\n\u003cp\u003eVITAL-T uses a special mix of natural ingredients, including botanicals like Fadogia agrestis and Fenugreek seed extract, along with carefully selected ingredients such as Tesnor®, Shoden® Ashwagandha, and Puremidine® Spermidine. All these ingredients work together to support your body's natural balance.\u003c\/p\u003e\n\u003ch3\u003eCore Vital T Supplement Facts\u003c\/h3\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/corevitalt_480x480.jpg?v=1749744159\" alt=\"\" style=\"float: none; display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/div\u003e\n\u003ch3\u003eCore Vital T Other Information\u003c\/h3\u003e\n\u003csection id=\"shopify-section-product-template\" class=\"shopify-section\"\u003e\n\u003cdiv class=\"section-product-template layout-4\" data-section-type=\"product\" data-section-id=\"product-template\"\u003e\n\u003cdiv class=\"container-wrapper\"\u003e\n\u003cdiv class=\"product-page-body\"\u003e\n\u003cdiv class=\"container\"\u003e\n\u003cdiv class=\"product-description\"\u003e\n\u003cdiv id=\"vitals-tabs-placeholder\" data-track-mid=\"33\" data-track-eid=\"1\"\u003e\n\u003cdiv class=\"vitals-tabs-container\"\u003e\n\u003cdiv id=\"tab-0\" class=\"vt-tab-content current\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Disclaimers in Vital T™?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\" dir=\"ltr\"\u003e\u003cspan\u003eYes, (California Residents) Prop 65 applies in this product. Consuming this supplement can expose you to chemicals including lead which is known in the state of California to cause cancer and birth defects or other reproductive harm. For more information, please visit www.p65warnings.ca.gov\/food.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\" dir=\"ltr\"\u003e\u003cspan\u003eAny statements made on this product page or on the product itself have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAre There Any Allergens In Vital T™?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"text-base font-normal text-gray-800 leading-[24px] pt-[9px] pb-[2px]\" dir=\"ltr\"\u003e\u003cstrong\u003eThis product claims none of the major allergens are present.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eHowever\u003cspan\u003e, this product is manufactured in a facility that processes all of the major allergens (milk, eggs, shellfish, tree nuts, peanuts, wheat, soybeans, sesame)\u003c\/span\u003e\u003cspan\u003e.\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eWhat is The Warning Statement On Vital T™?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eKEEP OUT OF THE REACH OF CHILDREN. Do not take this product if pregnant or breastfeeding. Only for use by individuals 18 years of age of older. Do not take this product before consulting a licensed, qualified health care professional if you are taking any other dietary supplement, prescription drug, over-the-counter medication; or if, you suspect you have treated for, diagnosed with or have a family history of any medical condition. Do not exceed recommended dosage or take with other stimulants or alcohol. Ensure you are properly hydrated before and after taking this product and during exercise. Do not take if dehydrated or in conditions of excessive heat. Discontinue 2 weeks prior to surgery. Immediately discontinue use and contact a medical doctor if you experience any adverse reaction to this product. Do not use if safety seal is broken or missing. Store in a cool and dry place.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv id=\"looxReviews\" data-product-id=\"7634226348274\" class=\"loox-reviews-default\"\u003e\u003c\/div\u003e\n\u003cdiv id=\"vitals-end-section\"\u003e\u003c\/div\u003e\n\u003c\/section\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":47650417639666,"sku":"corevitalt","price":64.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/files\/CORE_VITALT_PI_1800x1800Large.jpg?v=1749744155"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0262\/1194\/2474\/collections\/1core.jpg?v=1603084161","url":"https:\/\/nutricartel.com\/collections\/core-nutritionals.oembed?page=6","provider":"NutriCartel","version":"1.0","type":"link"}